iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020620

Ensembl Protein ID

ENSCAFP00000019298.2

UniProt Accession

E2RJ78; E2RJ78_CANLF

Genbank Protein ID

ENSCAFP00000019298

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AAEX03014562

Gene Name

ING5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000013088.2	ENSCAFT00000020786.2	ENSCAFP00000019298.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.30e-09	37.1	187	234

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C  ewfH+aC+ l+   ++p+ + w+Cp+C +
   Q: 187  TYC-LCHQVSYGE--MIGCDNpdCPiEWFHFACVDLT---TKPKGK-WFCPRCVQ 234
           69*.*******99..*********99***********...999997.******87 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MATAMYLEHY LDSIENLPCE LQRNFQLMRE LDQRTEDKKA EIDILAAEYI STVKTLSPDQ 60
RVEHLQKIQS AYSKCKEYSD DKVQLAMQTY EMVDKHIRRL DADLARFEAD LKDKMEGSDF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGACCG CCATGTACTT GGAGCACTAC CTGGACAGTA AGCGCCCCTC ACGGCCCTCG 60
GGCCCGGCGC CCGCGCCCCG AGCCCCCCCG NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028638--ING5
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016573--P:histone acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:2001235--P:positive regulation of apoptotic signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002381	Ailuropoda melanoleuca	97.81	2.00e-112	398.00
IUUC-Atr-002906	Amborella trichopoda	34.15	2.00e-34	139.00
IUUC-Apl-003516	Anas platyrhynchos	90.69	5.00e-99	353.00
IUUC-Aca-005009	Anolis carolinensis	85.29	2.00e-111	394.00
IUUC-Ame-011879	Astyanax mexicanus	75.52	3.00e-104	370.00
IUUC-Bta-012590	Bos taurus	97.36	2.00e-116	411.00
IUUC-Cja-019518	Callithrix jacchus	97.08	8.00e-124	436.00
IUUC-Cpo-022085	Cavia porcellus	98.31	1.00e-119	422.00
IUUC-Csa-023421	Chlorocebus sabaeus	98.33	4.00e-121	427.00
IUUC-Dre-027588	Danio rerio	77.27	5.00e-105	373.00
IUUC-Dor-030910	Dipodomys ordii	67.84	6.00e-85	306.00
IUUC-Eca-033493	Equus caballus	98.24	2.00e-121	427.00
IUUC-Fca-035635	Felis catus	97.27	5.00e-57	214.00
IUUC-Fal-036998	Ficedula albicollis	90.43	1.00e-113	401.00
IUUC-Gmo-039035	Gadus morhua	77.18	3.00e-103	367.00
IUUC-Gga-040578	Gallus gallus	90.83	4.00e-122	430.00
IUUC-Gac-042172	Gasterosteus aculeatus	74.69	2.00e-104	371.00
IUUC-Hsa-045965	Homo sapiens	98.33	4.00e-121	427.00
IUUC-Loc-052725	Lepisosteus oculatus	83.33	5.00e-105	373.00
IUUC-Mcc-055455	Macaca mulatta	97.38	8.00e-113	399.00
IUUC-Mtr-058089	Medicago truncatula	32.51	5.00e-35	140.00
IUUC-Mga-059312	Meleagris gallopavo	89.60	2.00e-98	351.00
IUUC-Mmr-061351	Microcebus murinus	97.36	1.00e-111	395.00
IUUC-Mdo-062282	Monodelphis domestica	95.83	1.00e-117	415.00
IUUC-Mmu-063201	Mus musculus	95.00	2.00e-123	434.00
IUUC-Mac-064625	Musa acuminata	34.38	3.00e-38	151.00
IUUC-Mpu-066302	Mustela putorius furo	99.17	8.00e-123	432.00
IUUC-Mlu-068192	Myotis lucifugus	98.33	2.00e-122	431.00
IUUC-Ont-072055	Oreochromis niloticus	78.01	4.00e-102	363.00
IUUC-Oan-073652	Ornithorhynchus anatinus	95.18	1.00e-113	402.00
IUUC-Ocu-073871	Oryctolagus cuniculus	96.27	7.00e-123	432.00
IUUC-Ola-087103	Oryzias latipes	75.62	4.00e-96	343.00
IUUC-Oga-088066	Otolemur garnettii	87.35	2.00e-103	367.00
IUUC-Ptr-091665	Pan troglodytes	98.33	4.00e-121	427.00
IUUC-Pan-091875	Papio anubis	98.33	4.00e-121	427.00
IUUC-Psi-093904	Pelodiscus sinensis	93.43	3.00e-106	377.00
IUUC-Pfo-096981	Poecilia formosa	78.42	4.00e-102	363.00
IUUC-Pca-100600	Procavia capensis	67.08	2.00e-89	321.00
IUUC-Pva-102282	Pteropus vampyrus	92.92	6.00e-127	446.00
IUUC-Rno-105646	Rattus norvegicus	94.58	6.00e-123	432.00
IUUC-Sha-107031	Sarcophilus harrisii	94.35	1.00e-109	389.00
IUUC-Smo-109441	Selaginella moellendorffii	35.77	1.00e-41	162.00
IUUC-Tgu-116837	Taeniopygia guttata	89.18	5.00e-113	399.00
IUUC-Tru-117974	Takifugu rubripes	76.45	2.00e-98	351.00
IUUC-Tni-120024	Tetraodon nigroviridis	75.93	6.00e-90	323.00
IUUC-Tca-121597	Theobroma cacao	34.84	1.00e-32	133.00
IUUC-Vvi-131487	Vitis vinifera	36.71	2.00e-34	139.00
IUUC-Xtr-132189	Xenopus tropicalis	84.10	7.00e-115	405.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence