iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132417

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAMC01036262

Gene Name

LONRF1; lonrf1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000005620.3	ENSXETT00000012392.2	ENSXETP00000012392.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	4.40e-09	36.5	363	410
E3 activity/RING/RING	1.80e-08	34.9	366	404

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqpltee 53
           +f C++ + l+ +Pv++p+G+t+ ++++e++l++  + cP+++++l+e 
   Q: 363  DFECSLCMRLFYEPVTTPCGHTFCKKCLERCLDHTPH-CPLCKESLSEF 410
           79***********************************.*******9875 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C+  f + p+++pCgH+f+++Cl++          + +CPlC+
   Q: 366  CSLCMRLFYE-PVTTPCGHTFCKKCLERC------LDHTPHCPLCK 404
           ****999977.***************999......9*********7 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

RPRQLGALLE YLVQKYSSWA AGGTVSRLEE GTFPLSCPGC GGFLREPVST QCGHTYCRCC 60
LRGEPRSRCR LCREDMGRSP RRTCVLLQQL ADKWFPPLLG TKSDRDDEVR QLLGAGAYAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGCCCAGGC AGCTCGGAGC GTTGCTGGAG TACCTAGTGC AAAAGTACAG CTCCTGGGCT 60
GCCGGAGGGA CGGTCAGTAG GCTTGAGGAG GGCACTTTCC CATTAAGCTG CCCGGGCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003111--Lon_substr-bd
IPR015947--PUA-like_domain
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51787--LON_N
PS50293--TPR_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02190--LON_substr_bdg

SMART

SM00464--LON
SM00184--RING

Gene Ontology

GO:0005622--C:intracellular
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001989	Ailuropoda melanoleuca	65.67	0.00e+00	691.00
IUUC-Apl-003309	Anas platyrhynchos	73.13	2.00e-164	571.00
IUUC-Aca-004288	Anolis carolinensis	58.68	0.00e+00	721.00
IUUC-Aly-005476	Arabidopsis lyrata	35.46	1.00e-37	150.00
IUUC-Ath-006654	Arabidopsis thaliana	35.86	8.00e-38	151.00
IUUC-Acl-008224	Aspergillus clavatus	28.19	2.00e-40	159.00
IUUC-Afu-008802	Aspergillus fumigatus	30.74	3.00e-39	156.00
IUUC-Ate-010489	Aspergillus terreus	32.78	4.00e-41	162.00
IUUC-Ame-010716	Astyanax mexicanus	50.52	6.00e-179	620.00
IUUC-Bta-012903	Bos taurus	62.06	0.00e+00	693.00
IUUC-Bdi-014333	Brachypodium distachyon	42.31	8.00e-42	164.00
IUUC-Cja-019312	Callithrix jacchus	57.27	0.00e+00	714.00
IUUC-Cfa-020159	Canis familiaris	63.31	0.00e+00	711.00
IUUC-Cpo-022528	Cavia porcellus	64.30	0.00e+00	667.00
IUUC-Cre-022730	Chlamydomonas reinhardtii	30.41	4.00e-12	65.10
IUUC-Csa-023361	Chlorocebus sabaeus	61.03	0.00e+00	665.00
IUUC-Cho-024549	Choloepus hoffmanni	58.05	3.00e-158	551.00
IUUC-Cgl-026514	Colletotrichum gloeosporioides	33.54	2.00e-44	173.00
IUUC-Cme-027153	Cyanidioschyzon merolae	29.87	8.00e-26	111.00
IUUC-Dre-028195	Danio rerio	49.71	0.00e+00	628.00
IUUC-Dno-029284	Dasypus novemcinctus	64.37	0.00e+00	687.00
IUUC-Dor-031123	Dipodomys ordii	59.74	3.00e-146	511.00
IUUC-Ete-032455	Echinops telfairi	71.46	7.00e-168	583.00
IUUC-Eca-033248	Equus caballus	69.17	5.00e-162	563.00
IUUC-Eeu-034441	Erinaceus europaeus	71.43	4.00e-171	593.00
IUUC-Fca-035551	Felis catus	65.30	0.00e+00	692.00
IUUC-Fal-036731	Ficedula albicollis	65.09	0.00e+00	691.00
IUUC-Gmo-039315	Gadus morhua	47.63	4.00e-160	558.00
IUUC-Gga-040888	Gallus gallus	73.90	5.00e-174	603.00
IUUC-Gac-042121	Gasterosteus aculeatus	49.03	5.00e-173	601.00
IUUC-Ggo-044985	Gorilla gorilla	62.08	0.00e+00	690.00
IUUC-Hsa-046592	Homo sapiens	56.73	0.00e+00	696.00
IUUC-Hvu-047145	Hordeum vulgare	43.80	8.00e-26	110.00
IUUC-Itr-048573	Ictidomys tridecemlineatus	62.91	0.00e+00	701.00
IUUC-Lch-050404	Latimeria chalumnae	54.03	0.00e+00	682.00
IUUC-Laf-053431	Loxodonta africana	65.55	0.00e+00	696.00
IUUC-Mcc-055751	Macaca mulatta	57.32	0.00e+00	655.00
IUUC-Mor-056963	Magnaporthe oryzae	43.28	8.00e-42	164.00
IUUC-Mtr-058075	Medicago truncatula	34.39	6.00e-42	164.00
IUUC-Mmr-061283	Microcebus murinus	62.56	0.00e+00	698.00
IUUC-Mmu-063169	Mus musculus	59.26	0.00e+00	682.00
IUUC-Mpu-066537	Mustela putorius furo	57.49	0.00e+00	702.00
IUUC-Mlu-067497	Myotis lucifugus	64.55	0.00e+00	689.00
IUUC-Nfi-068337	Neosartorya fischeri	30.72	2.00e-39	156.00
IUUC-Nle-068971	Nomascus leucogenys	64.11	0.00e+00	667.00
IUUC-Opr-070791	Ochotona princeps	66.60	0.00e+00	628.00
IUUC-Ont-071548	Oreochromis niloticus	50.51	8.00e-178	617.00
IUUC-Oan-072747	Ornithorhynchus anatinus	71.64	1.00e-171	595.00
IUUC-Ocu-074928	Oryctolagus cuniculus	72.18	2.00e-170	591.00
IUUC-Oba-075239	Oryza barthii	41.20	7.00e-43	167.00
IUUC-Obr-076158	Oryza brachyantha	40.72	1.00e-42	167.00
IUUC-Ogu-078154	Oryza glumaepatula	41.67	3.00e-43	169.00
IUUC-Oin-079067	Oryza indica	41.20	5.00e-43	169.00
IUUC-Olo-080663	Oryza longistaminata	41.67	3.00e-43	169.00
IUUC-Oni-082119	Oryza nivara	41.20	6.00e-43	168.00
IUUC-Opu-083266	Oryza punctata	43.04	4.00e-32	132.00
IUUC-Oru-085190	Oryza rufipogon	41.20	1.00e-42	167.00
IUUC-Ola-086977	Oryzias latipes	49.17	3.00e-174	605.00
IUUC-Oga-088719	Otolemur garnettii	61.99	0.00e+00	699.00
IUUC-Oar-089577	Ovis aries	65.43	0.00e+00	687.00
IUUC-Ptr-090711	Pan troglodytes	61.54	0.00e+00	694.00
IUUC-Pan-092587	Papio anubis	61.03	0.00e+00	681.00
IUUC-Psi-093128	Pelodiscus sinensis	63.31	0.00e+00	698.00
IUUC-Ppa-095945	Physcomitrella patens	31.21	2.00e-09	56.60
IUUC-Pfo-096474	Poecilia formosa	48.81	3.00e-175	608.00
IUUC-Pab-097800	Pongo abelii	56.77	0.00e+00	689.00
IUUC-Pgr-103289	Puccinia graminis	27.60	5.00e-27	115.00
IUUC-Ptt-103898	Puccinia triticina	27.63	1.00e-26	114.00
IUUC-Rno-105718	Rattus norvegicus	64.11	0.00e+00	664.00
IUUC-Sja-107742	Schizosaccharomyces japonicus	36.18	7.00e-30	124.00
IUUC-Sit-110495	Setaria italica	41.12	1.00e-42	167.00
IUUC-Stu-112446	Solanum tuberosum	38.96	7.00e-12	64.70
IUUC-Sar-113220	Sorex araneus	70.28	7.00e-158	549.00
IUUC-Sbi-114779	Sorghum bicolor	40.99	6.00e-30	124.00
IUUC-Sre-114977	Sporisorium reilianum	32.62	4.00e-35	143.00
IUUC-Ssc-115733	Sus scrofa	60.80	0.00e+00	704.00
IUUC-Tgu-117431	Taeniopygia guttata	59.43	0.00e+00	710.00
IUUC-Tru-118274	Takifugu rubripes	49.48	1.00e-175	609.00
IUUC-Tsy-119043	Tarsius syrichta	64.11	0.00e+00	682.00
IUUC-Tni-120766	Tetraodon nigroviridis	48.43	1.00e-162	566.00
IUUC-Tca-121632	Theobroma cacao	33.44	2.00e-44	173.00
IUUC-Tre-121992	Trichoderma reesei	30.61	2.00e-08	53.50
IUUC-Tae-124676	Triticum aestivum	34.26	8.00e-43	167.00
IUUC-Tur-126297	Triticum urartu	43.21	7.00e-34	138.00
IUUC-Tme-127112	Tuber melanosporum	37.99	1.00e-46	180.00
IUUC-Tbe-127284	Tupaia belangeri	71.11	1.00e-165	575.00
IUUC-Vpa-130408	Vicugna pacos	59.81	1.00e-174	605.00
IUUC-Vvi-130910	Vitis vinifera	34.60	2.00e-39	157.00
IUUC-Xma-134099	Xiphophorus maculatus	48.96	7.00e-177	613.00
IUUC-Zma-135914	Zea mays	43.80	7.00e-26	111.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence