iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-023809

Ensembl Protein ID

ENSCSAP00000012158.1

UniProt Accession

A0A0D9RU69; A0A0D9RU69_CHLSB

Genbank Protein ID

ENSCSAP00000012158

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01148161

Gene Name

TRAF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000016084.1	ENSCSAT00000014178.1	ENSCSAP00000012158.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	97.31	0.00e+00	902.00	IUUC-Hsa-046952

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MRKFKETAVW SSGPQNCAAC VHEGIYEEGI SILESSSAFP DNAARREVES LPAVCPIDGC 60
TWKGTLKEYE SCHEGRCPLM LTECPACKGL VRLGEKERHL EHECPERSLS CRHCRAPCCG 120

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Nucleotide Sequence
(Fasta)

TGGGGAGAGC CGGCAGCACC TGAGTTACTG CAGCCAGTGT CCTTGGCAGT TCAGGCGCGC 60
CTTCTTCACA ATCGGGGAGC GATAGAAACA TTGTCCTGTG AATATTGGGA TTTAAAACAT 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027133--TRAF2
IPR032070--TRAF_BIRC3-bd
IPR013083--Znf_RING/FYVE/PHD
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS50145--ZF_TRAF

Pfam

PF16673--TRAF_BIRC3_bd
PF02176--zf-TRAF

SMART

SM00061--MATH

Gene Ontology

GO:1990597--C:AIP1-IRE1 complex
GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005829--C:cytosol
GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:0045121--C:membrane raft
GO:0097057--C:TRAF2-GSTP1 complex
GO:0000151--C:ubiquitin ligase complex
GO:0012506--C:vesicle membrane
GO:0046625--F:sphingolipid binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0043623--P:cellular protein complex assembly
GO:0071732--P:cellular response to nitric oxide
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:1903721--P:positive regulation of I-kappaB phosphorylation
GO:0032743--P:positive regulation of interleukin-2 production
GO:0043507--P:positive regulation of JUN kinase activity
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0002726--P:positive regulation of T cell cytokine production
GO:1903265--P:positive regulation of tumor necrosis factor-mediated signaling pathway
GO:0097300--P:programmed necrotic cell death
GO:0051865--P:protein autoubiquitination
GO:0030163--P:protein catabolic process
GO:0070207--P:protein homotrimerization
GO:0070534--P:protein K63-linked ubiquitination
GO:0051023--P:regulation of immunoglobulin secretion
GO:0033209--P:tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002344	Ailuropoda melanoleuca	85.16	0.00e+00	792.00
IUUC-Apl-004202	Anas platyrhynchos	74.21	0.00e+00	726.00
IUUC-Aca-005029	Anolis carolinensis	57.64	3.00e-123	435.00
IUUC-Ame-011841	Astyanax mexicanus	55.88	2.00e-161	562.00
IUUC-Bta-013180	Bos taurus	84.38	0.00e+00	781.00
IUUC-Cja-019813	Callithrix jacchus	95.52	0.00e+00	889.00
IUUC-Cfa-021205	Canis familiaris	90.85	0.00e+00	827.00
IUUC-Cpo-021346	Cavia porcellus	87.67	0.00e+00	806.00
IUUC-Dre-027669	Danio rerio	59.91	6.00e-161	560.00
IUUC-Dno-029458	Dasypus novemcinctus	82.97	0.00e+00	780.00
IUUC-Dor-030338	Dipodomys ordii	84.30	0.00e+00	712.00
IUUC-Eca-034401	Equus caballus	89.71	0.00e+00	830.00
IUUC-Eeu-034668	Erinaceus europaeus	70.68	2.00e-107	382.00
IUUC-Fca-036057	Felis catus	86.02	0.00e+00	816.00
IUUC-Fal-037560	Ficedula albicollis	72.54	0.00e+00	634.00
IUUC-Gmo-038964	Gadus morhua	64.40	6.00e-171	593.00
IUUC-Gga-040425	Gallus gallus	74.95	0.00e+00	724.00
IUUC-Gac-041908	Gasterosteus aculeatus	64.86	4.00e-174	604.00
IUUC-Ggo-044606	Gorilla gorilla	88.71	0.00e+00	808.00
IUUC-Hsa-046952	Homo sapiens	97.31	0.00e+00	902.00
IUUC-Itr-049016	Ictidomys tridecemlineatus	79.08	0.00e+00	721.00
IUUC-Lch-049571	Latimeria chalumnae	58.53	1.00e-176	612.00
IUUC-Loc-051973	Lepisosteus oculatus	63.64	5.00e-165	573.00
IUUC-Laf-053815	Loxodonta africana	82.48	0.00e+00	739.00
IUUC-Mcc-054888	Macaca mulatta	98.43	0.00e+00	914.00
IUUC-Meu-056547	Macropus eugenii	74.43	0.00e+00	665.00
IUUC-Mga-059819	Meleagris gallopavo	74.72	0.00e+00	687.00
IUUC-Mdo-062570	Monodelphis domestica	80.86	0.00e+00	747.00
IUUC-Mmu-063133	Mus musculus	85.65	0.00e+00	760.00
IUUC-Mpu-065802	Mustela putorius furo	86.96	0.00e+00	823.00
IUUC-Nle-070155	Nomascus leucogenys	97.31	0.00e+00	904.00
IUUC-Opr-070856	Ochotona princeps	87.28	2.00e-115	409.00
IUUC-Ont-071930	Oreochromis niloticus	65.39	0.00e+00	629.00
IUUC-Ola-087397	Oryzias latipes	61.68	7.00e-175	607.00
IUUC-Oga-088109	Otolemur garnettii	93.72	0.00e+00	872.00
IUUC-Oar-090310	Ovis aries	73.72	0.00e+00	684.00
IUUC-Ptr-090643	Pan troglodytes	97.53	0.00e+00	904.00
IUUC-Pan-091933	Papio anubis	98.21	0.00e+00	912.00
IUUC-Psi-093681	Pelodiscus sinensis	73.88	0.00e+00	682.00
IUUC-Pfo-096148	Poecilia formosa	61.26	2.00e-176	612.00
IUUC-Pab-098631	Pongo abelii	97.31	0.00e+00	904.00
IUUC-Pca-100582	Procavia capensis	67.05	2.00e-89	322.00
IUUC-Pva-102396	Pteropus vampyrus	72.42	0.00e+00	631.00
IUUC-Rno-106120	Rattus norvegicus	85.20	0.00e+00	746.00
IUUC-Sce-106423	Saccharomyces cerevisiae	23.89	1.50e-01	33.10
IUUC-Sha-106493	Sarcophilus harrisii	82.66	0.00e+00	769.00
IUUC-Sar-113570	Sorex araneus	93.92	2.00e-100	358.00
IUUC-Ssc-115843	Sus scrofa	83.77	0.00e+00	800.00
IUUC-Tgu-117144	Taeniopygia guttata	69.09	3.00e-174	604.00
IUUC-Tru-117853	Takifugu rubripes	62.74	1.00e-176	612.00
IUUC-Tni-120256	Tetraodon nigroviridis	65.91	0.00e+00	636.00
IUUC-Tbe-127943	Tupaia belangeri	66.67	6.00e-102	363.00
IUUC-Ttr-129246	Tursiops truncatus	87.75	0.00e+00	790.00
IUUC-Xtr-132279	Xenopus tropicalis	59.05	4.00e-147	514.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence