iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ppe-101495

Ensembl Protein ID

EMJ10321

UniProt Accession

M5WAI2; M5WAI2_PRUPE

Genbank Protein ID

EMJ10321.1

Protein Name

Presenilin

Genbank Nucleotide ID

KB639086

Gene Name

PS1; PRUPE_ppa005461mg

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PRUPE_ppa005461mg	EMJ10321	EMJ10321

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/CUE	29.70	2.00e-39	160.00	IUUC-Cel-018553
UBD/Alpha-Helix/CUE	30.72	2.00e-29	128.00	IUUC-Dre-028689

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Prunus persica

Functional Description
(View)

Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.

Protein Sequence
(Fasta)

MESSILESIG VEIIGVMSPV SICMLLVVLL VYALSPSNPF SAAASAPPIR TAANLVYLES 60
PSDSASQKLE GALLNALVFV VLIAIVTFLL VLLYYYNFTN FLKNYMRFSA FFVLGTMGGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAAATGCGG TAACCATCCC CACACAGACA CCTACCAAGT GCTCGACGAA AGTCCCCAAC 60
GAAACAAAAC CATGGAGTCG AGCATCCTAG AGTCGATCGG CGTTGAGATT ATCGGCGTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0333--Golgi apparatus
KW-0378--Hydrolase
KW-0472--Membrane
KW-0914--Notch signaling pathway
KW-0645--Protease
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001108--Peptidase_A22A
IPR006639--Preselin/SPP

Pfam

PF01080--Presenilin

PRINTS

PR01072--PRESENILIN

SMART

SM00730--PSN

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0004190--F:aspartic-type endopeptidase activity
GO:0007219--P:Notch signaling pathway
GO:0016485--P:protein processing

KEGG

pper:PRUPE_ppa005461mg

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000686	Aegilops tauschii	51.36	4.00e-85	308.00
IUUC-Aml-001648	Ailuropoda melanoleuca	37.76	2.00e-35	142.00
IUUC-Atr-003039	Amborella trichopoda	60.20	6.00e-142	496.00
IUUC-Apl-003727	Anas platyrhynchos	34.15	3.00e-33	135.00
IUUC-Aca-004582	Anolis carolinensis	31.70	3.00e-34	138.00
IUUC-Aly-005455	Arabidopsis lyrata	64.82	7.00e-143	499.00
IUUC-Ath-006730	Arabidopsis thaliana	64.56	4.00e-144	503.00
IUUC-Ame-010686	Astyanax mexicanus	31.08	2.00e-24	105.00
IUUC-Bta-013026	Bos taurus	37.16	5.00e-35	141.00
IUUC-Bdi-014196	Brachypodium distachyon	55.39	5.00e-101	360.00
IUUC-Bol-015841	Brassica oleracea	62.80	2.00e-130	457.00
IUUC-Bra-017580	Brassica rapa	74.07	4.00e-68	250.00
IUUC-Cel-018553	Caenorhabditis elegans	29.89	1.00e-41	162.00
IUUC-Cja-019994	Callithrix jacchus	32.14	7.00e-36	144.00
IUUC-Cfa-020074	Canis familiaris	33.04	2.00e-36	146.00
IUUC-Cpo-022237	Cavia porcellus	33.71	3.00e-36	145.00
IUUC-Cre-022747	Chlamydomonas reinhardtii	44.49	1.00e-48	187.00
IUUC-Csa-023537	Chlorocebus sabaeus	33.18	8.00e-36	144.00
IUUC-Cho-024735	Choloepus hoffmanni	34.44	3.00e-30	125.00
IUUC-Cin-025780	Ciona intestinalis	31.95	5.00e-43	167.00
IUUC-Csv-025967	Ciona savignyi	33.03	2.00e-25	108.00
IUUC-Dre-028689	Danio rerio	32.94	5.00e-31	127.00
IUUC-Dno-029758	Dasypus novemcinctus	33.11	1.00e-35	143.00
IUUC-Dor-031127	Dipodomys ordii	37.30	8.00e-24	103.00
IUUC-Dme-031929	Drosophila melanogaster	34.23	3.00e-27	115.00
IUUC-Ete-032487	Echinops telfairi	36.15	7.00e-17	80.90
IUUC-Eca-034387	Equus caballus	37.02	6.00e-27	114.00
IUUC-Eeu-035134	Erinaceus europaeus	35.59	4.00e-34	137.00
IUUC-Fca-036243	Felis catus	33.85	1.00e-36	146.00
IUUC-Fal-036600	Ficedula albicollis	31.32	2.00e-34	139.00
IUUC-Gmo-038550	Gadus morhua	35.33	8.00e-24	103.00
IUUC-Gga-040993	Gallus gallus	31.32	4.00e-35	141.00
IUUC-Gac-042511	Gasterosteus aculeatus	30.38	1.00e-33	136.00
IUUC-Gma-043822	Glycine max	72.66	5.00e-61	227.00
IUUC-Ggo-044859	Gorilla gorilla	31.96	3.00e-24	105.00
IUUC-Hsa-046822	Homo sapiens	33.18	9.00e-36	143.00
IUUC-Hvu-047141	Hordeum vulgare	52.40	9.00e-93	333.00
IUUC-Itr-048420	Ictidomys tridecemlineatus	35.48	5.00e-37	147.00
IUUC-Lch-049638	Latimeria chalumnae	32.88	2.00e-27	115.00
IUUC-Lpe-051132	Leersia perrieri	54.98	1.00e-96	345.00
IUUC-Loc-052427	Lepisosteus oculatus	30.51	2.00e-27	116.00
IUUC-Laf-053979	Loxodonta africana	37.22	3.00e-33	135.00
IUUC-Mcc-055682	Macaca mulatta	33.18	9.00e-36	143.00
IUUC-Meu-056004	Macropus eugenii	33.71	4.00e-22	98.20
IUUC-Mtr-058392	Medicago truncatula	64.16	4.00e-125	440.00
IUUC-Mga-059466	Meleagris gallopavo	31.10	2.00e-34	139.00
IUUC-Mmr-060890	Microcebus murinus	36.46	2.00e-26	112.00
IUUC-Mdo-062122	Monodelphis domestica	35.65	4.00e-35	141.00
IUUC-Mmu-063176	Mus musculus	32.06	1.00e-33	136.00
IUUC-Mac-064858	Musa acuminata	70.25	9.00e-42	162.00
IUUC-Mpu-065927	Mustela putorius furo	36.04	7.00e-36	144.00
IUUC-Mlu-067079	Myotis lucifugus	33.41	1.00e-41	163.00
IUUC-Nle-070180	Nomascus leucogenys	33.18	9.00e-36	143.00
IUUC-Opr-070847	Ochotona princeps	34.55	3.00e-22	98.60
IUUC-Ont-071846	Oreochromis niloticus	30.80	6.00e-32	131.00
IUUC-Oan-072783	Ornithorhynchus anatinus	34.44	4.00e-33	134.00
IUUC-Ocu-074527	Oryctolagus cuniculus	35.93	7.00e-36	144.00
IUUC-Oba-075256	Oryza barthii	53.64	2.00e-85	308.00
IUUC-Obr-076302	Oryza brachyantha	54.57	1.00e-92	332.00
IUUC-Ogl-077097	Oryza glaberrima	53.49	1.00e-95	342.00
IUUC-Ogu-078570	Oryza glumaepatula	55.26	1.00e-92	332.00
IUUC-Oin-079244	Oryza indica	53.70	4.00e-96	344.00
IUUC-Olo-080484	Oryza longistaminata	53.25	2.00e-64	237.00
IUUC-Ome-081814	Oryza meridionalis	53.60	7.00e-98	350.00
IUUC-Oni-082057	Oryza nivara	55.50	4.00e-93	334.00
IUUC-Opu-084176	Oryza punctata	53.92	2.00e-93	335.00
IUUC-Oru-084618	Oryza rufipogon	55.50	7.00e-93	333.00
IUUC-Osa-085602	Oryza sativa	55.11	7.00e-94	336.00
IUUC-Ola-086707	Oryzias latipes	33.18	5.00e-25	107.00
IUUC-Olu-087811	Ostreococcus lucimarinus	43.10	2.00e-45	175.00
IUUC-Oga-088560	Otolemur garnettii	35.91	6.00e-26	110.00
IUUC-Oar-090348	Ovis aries	32.37	9.00e-38	150.00
IUUC-Ptr-091060	Pan troglodytes	33.18	9.00e-36	143.00
IUUC-Pan-091855	Papio anubis	32.29	1.00e-34	139.00
IUUC-Psi-093505	Pelodiscus sinensis	31.84	2.00e-36	146.00
IUUC-Pma-094612	Petromyzon marinus	35.22	2.00e-22	99.80
IUUC-Ppa-095431	Physcomitrella patens	47.22	4.00e-96	344.00
IUUC-Pfo-097396	Poecilia formosa	31.40	2.00e-36	145.00
IUUC-Pab-098591	Pongo abelii	32.96	8.00e-36	144.00
IUUC-Pop-099661	Populus trichocarpa	46.97	2.00e-87	315.00
IUUC-Pca-101029	Procavia capensis	35.74	2.00e-35	142.00
IUUC-Pva-102934	Pteropus vampyrus	34.81	1.00e-25	110.00
IUUC-Rno-105861	Rattus norvegicus	40.58	2.00e-23	103.00
IUUC-Sha-107045	Sarcophilus harrisii	32.44	2.00e-35	142.00
IUUC-Smo-109325	Selaginella moellendorffii	53.71	8.00e-44	170.00
IUUC-Sit-110624	Setaria italica	54.91	9.00e-96	343.00
IUUC-Sly-110865	Solanum lycopersicum	88.57	1.00e-32	130.00
IUUC-Stu-112433	Solanum tuberosum	54.22	6.00e-101	360.00
IUUC-Sar-113169	Sorex araneus	35.15	7.00e-32	130.00
IUUC-Sbi-114305	Sorghum bicolor	56.54	1.00e-96	345.00
IUUC-Ssc-115766	Sus scrofa	38.25	2.00e-36	145.00
IUUC-Tgu-116469	Taeniopygia guttata	33.43	5.00e-34	137.00
IUUC-Tru-117732	Takifugu rubripes	31.44	1.00e-31	129.00
IUUC-Tsy-119624	Tarsius syrichta	45.79	1.00e-22	99.80
IUUC-Tni-119852	Tetraodon nigroviridis	31.33	5.00e-30	124.00
IUUC-Tca-121865	Theobroma cacao	77.37	1.00e-155	541.00
IUUC-Tae-125925	Triticum aestivum	51.76	8.00e-93	333.00
IUUC-Tur-126237	Triticum urartu	51.73	3.00e-83	301.00
IUUC-Tbe-128148	Tupaia belangeri	37.50	7.00e-24	103.00
IUUC-Ttr-128793	Tursiops truncatus	36.56	5.00e-35	141.00
IUUC-Vpa-130625	Vicugna pacos	33.93	7.00e-31	127.00
IUUC-Vvi-131312	Vitis vinifera	73.99	1.00e-148	518.00
IUUC-Xtr-132756	Xenopus tropicalis	32.60	1.00e-36	146.00
IUUC-Xma-133377	Xiphophorus maculatus	30.87	4.00e-36	144.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence