iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066380

Ensembl Protein ID

ENSMPUP00000009830.1

UniProt Accession

M3YES3; M3YES3_MUSPF

Genbank Protein ID

ENSMPUP00000009830

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01016760

Gene Name

KLHL3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000009905.1	ENSMPUT00000009990.1	ENSMPUP00000009830.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.30e-21	76.8	64	130
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.40e-11	43.4	163	194

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dv++v +++e++ah++vLaa+S++F a+f+++++esk  +++eikdv+   ++ l++++Yt +++ +
   Q: 64   CDVMIVAEDVEIEAHRVVLAACSPYFCAMFTGDMSESK-AKKIEIKDVDGRTLNKLIDYIYTAEIEVT 130
           8*************************************.************************99876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           + Nclgi++fAd ++c+dL ++a+ ++++hF+
   Q: 163  PTNCLGIRAFADVHTCTDLLQQANAYAEQHFP 194
           78*****************************6 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MHSSAAATPA GPRTMDGESI KLSSQPPVQA GGDEKNQRTI TVNSAHMGKA FKVMNELRSK 60
QLLCDVMIVA EDVEIEAHRV VLAACSPYFC AMFTGDMSES KAKKIEIKDV DGRTLNKLID 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCGAGGCTC AGCAGCTGGA GATAACAGGG TATGAGACAT CTCTGGCTGG AGATGAGGGT 60
TCATTGGGAG ACTTACTAGT TGGAGCCACA GCTGAAGTTA AAATTTCAGT GCTTTTGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0072156--P:distal tubule morphogenesis
GO:0050801--P:ion homeostasis
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0070294--P:renal sodium ion absorption

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001632	Ailuropoda melanoleuca	98.63	0.00e+00	1176.00
IUUC-Apl-003965	Anas platyrhynchos	94.85	0.00e+00	1106.00
IUUC-Aca-004912	Anolis carolinensis	94.38	0.00e+00	1107.00
IUUC-Ate-010500	Aspergillus terreus	25.56	1.00e-19	90.90
IUUC-Ame-010670	Astyanax mexicanus	81.55	0.00e+00	945.00
IUUC-Bta-013354	Bos taurus	97.95	0.00e+00	1168.00
IUUC-Bra-017771	Brassica rapa	29.36	1.00e-12	68.60
IUUC-Cel-018136	Caenorhabditis elegans	42.66	1.00e-130	459.00
IUUC-Cja-019183	Callithrix jacchus	93.39	0.00e+00	1023.00
IUUC-Cfa-020465	Canis familiaris	98.28	0.00e+00	1171.00
IUUC-Cpo-022115	Cavia porcellus	97.43	0.00e+00	1166.00
IUUC-Csa-024219	Chlorocebus sabaeus	97.96	0.00e+00	1179.00
IUUC-Csv-026032	Ciona savignyi	60.61	0.00e+00	705.00
IUUC-Cgl-026620	Colletotrichum gloeosporioides	30.42	9.00e-25	107.00
IUUC-Dre-028524	Danio rerio	75.04	0.00e+00	946.00
IUUC-Dno-029075	Dasypus novemcinctus	99.29	0.00e+00	1143.00
IUUC-Dor-030156	Dipodomys ordii	80.96	0.00e+00	944.00
IUUC-Ete-033064	Echinops telfairi	83.21	0.00e+00	863.00
IUUC-Eca-033887	Equus caballus	96.59	0.00e+00	1162.00
IUUC-Eeu-035244	Erinaceus europaeus	78.71	0.00e+00	930.00
IUUC-Fca-035375	Felis catus	98.63	0.00e+00	1175.00
IUUC-Fal-037119	Ficedula albicollis	96.22	0.00e+00	1071.00
IUUC-Fso-038219	Fusarium solani	40.32	2.00e-10	57.00
IUUC-Gga-041094	Gallus gallus	95.80	0.00e+00	1102.00
IUUC-Gac-042585	Gasterosteus aculeatus	75.88	0.00e+00	914.00
IUUC-Ggo-045485	Gorilla gorilla	97.29	0.00e+00	1168.00
IUUC-Hsa-046717	Homo sapiens	97.79	0.00e+00	1178.00
IUUC-Itr-048605	Ictidomys tridecemlineatus	97.77	0.00e+00	1169.00
IUUC-Lch-050246	Latimeria chalumnae	85.55	0.00e+00	1003.00
IUUC-Laf-053700	Loxodonta africana	97.41	0.00e+00	1147.00
IUUC-Mcc-054732	Macaca mulatta	98.81	0.00e+00	1021.00
IUUC-Mga-059994	Meleagris gallopavo	93.48	0.00e+00	992.00
IUUC-Mdo-062923	Monodelphis domestica	96.59	0.00e+00	1161.00
IUUC-Mmu-063842	Mus musculus	96.24	0.00e+00	1154.00
IUUC-Mlu-067922	Myotis lucifugus	97.92	0.00e+00	1150.00
IUUC-Nle-069761	Nomascus leucogenys	97.79	0.00e+00	1176.00
IUUC-Opr-070287	Ochotona princeps	88.76	0.00e+00	1041.00
IUUC-Ont-071654	Oreochromis niloticus	78.22	0.00e+00	961.00
IUUC-Ocu-074957	Oryctolagus cuniculus	96.92	0.00e+00	1154.00
IUUC-Ola-086853	Oryzias latipes	78.89	0.00e+00	911.00
IUUC-Oga-088559	Otolemur garnettii	97.45	0.00e+00	1169.00
IUUC-Oar-089925	Ovis aries	97.79	0.00e+00	1177.00
IUUC-Ptr-091487	Pan troglodytes	97.79	0.00e+00	1178.00
IUUC-Pan-091705	Papio anubis	97.96	0.00e+00	1179.00
IUUC-Psi-093478	Pelodiscus sinensis	91.15	0.00e+00	1052.00
IUUC-Pfo-097450	Poecilia formosa	80.84	0.00e+00	900.00
IUUC-Pab-097618	Pongo abelii	97.61	0.00e+00	1175.00
IUUC-Pca-100739	Procavia capensis	88.80	0.00e+00	661.00
IUUC-Sha-106935	Sarcophilus harrisii	98.93	0.00e+00	757.00
IUUC-Ssc-115599	Sus scrofa	98.28	0.00e+00	1173.00
IUUC-Tgu-117001	Taeniopygia guttata	95.22	0.00e+00	1083.00
IUUC-Tru-118078	Takifugu rubripes	79.79	0.00e+00	950.00
IUUC-Tsy-119161	Tarsius syrichta	85.47	0.00e+00	899.00
IUUC-Tni-120888	Tetraodon nigroviridis	77.37	0.00e+00	889.00
IUUC-Tbe-127285	Tupaia belangeri	83.66	0.00e+00	678.00
IUUC-Ttr-128884	Tursiops truncatus	82.35	7.00e-154	537.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence