iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012321

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02045484

Gene Name

USP30

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000019845.5	ENSBTAT00000029564.4	ENSBTAP00000029563.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.60e-70	236.3	69	501

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgy 87
           Gl NlgNtC+mNS+LQ Ls++p + + l e +++ +   +++ +++ l+ +l +l+++l     +++++ + + ll++l+++  ++s++
   Q: 69   GLVNLGNTCFMNSLLQGLSACPTFIKWLEEFTTQYTGGHKEPPQHQYLSLTLLHLLKALScqeVTDEEVLDASCLLDVLRMYRWQISSF 157
           9*****************************7777777888889999*************888899999********************* PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..........aeekkkkknkslisdlFqgqlksqikclecdnvs.sr 165
           e+qDa+E+++++ ++le+e    ++ +++++++ ++ e++ e          + + ++++n+   ++ F+g+l+s+++c++c+++s +r
   Q: 158  EEQDAHELFHVITSSLEDER--DRQPRVTHLFDVHSLEQQTEitprqitcrtRGSPHPTSNHWKSQHPFHGRLTSNMVCKHCEHQSpVR 244
           *******************9..668888899999888888888999999999999********************************** PP
   S: 166  eepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekck...............kkqeaekklklkklPevLilhLkRfsf 239
           +++f +lsl++p ++  ++++l++cL++f + e++++   + c++c+               ++++ +k+lkl klP++L++hL+R s+
   Q: 245  FDTFDSLSLSIPASTWGHPLTLDHCLHHFISSESVRD---VVCDNCTkieakgtlngekvehQRTTFVKQLKLGKLPQCLCIHLQRLSW 330
           ***********************************97...9******8888888888888777777*********************** PP
   S: 240  seeqksrekinkkvefpleLdlspfcts.............................................peekqke......... 274
           s++ + + k +++v+f + L ++ +  +                                                   +         
   Q: 331  SSH-GTPLKRHEHVQFGEFLMMDIYKYHllghkpghrspkqcekagpalelqdgpaapksvrnhpggpktqifM-----Ngacspsllp 413
           998.8888*********888888666666678888877777766666666666666666555555555555550.....0555555555 PP
   S: 275  ...................kkkYeLiavvvHsGslssGHYvayvkn.........ekgkWllfdDskVtevkeeevleetgstaYvlfY 335
                              ++ ++L+avvvH+G ++sGH+v+y ++          + +Wl ++D++V++ + +evl+   s+aY+lfY
   Q: 414  alptpmpfplpavpdysssTYLFQLMAVVVHHGDMHSGHFVTYRRSppsaknpvsASSQWLWVSDDTVRKASLQEVLS---SSAYLLFY 499
           55555555555555555559999***********************8888887777888*******************...******** PP
   S: 336  kr 337
           +r
   Q: 500  ER 501
           98 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MLSSRASAAM TAADRAIQRF LRTGAAVRYK VMKNWGVIGG IAAALAAGIY VIWGPITERK 60
KRRKGLVPGL VNLGNTCFMN SLLQGLSACP TFIKWLEEFT TQYTGGHKEP PQHQYLSLTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCAGGCAGC CCGTCCGTTG GTCTACCCTC CCCGGAGGAG CTGGGGCTTT GGCCACGGGT 60
TCCGCCGCCT CGGGAACCCT CGGAGCCCTG GGTCCGGCCG CGGCGACCGC GGCGGGGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005741--C:mitochondrial outer membrane
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008053--P:mitochondrial fusion
GO:0000422--P:mitophagy
GO:0035871--P:protein K11-linked deubiquitination
GO:0044313--P:protein K6-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000204	Aegilops tauschii	27.48	2.00e-15	76.60
IUUC-Aml-001733	Ailuropoda melanoleuca	92.12	0.00e+00	861.00
IUUC-Atr-002510	Amborella trichopoda	24.08	2.00e-22	100.00
IUUC-Apl-003645	Anas platyrhynchos	71.33	2.00e-105	374.00
IUUC-Aca-004583	Anolis carolinensis	65.79	1.00e-23	100.00
IUUC-Aly-005754	Arabidopsis lyrata	25.05	8.00e-25	108.00
IUUC-Ath-007622	Arabidopsis thaliana	25.82	2.00e-22	100.00
IUUC-Ame-010896	Astyanax mexicanus	61.47	1.00e-152	533.00
IUUC-Bdi-014795	Brachypodium distachyon	28.25	9.00e-18	84.70
IUUC-Bol-015637	Brassica oleracea	26.19	1.00e-23	103.00
IUUC-Bra-016801	Brassica rapa	25.93	4.00e-24	105.00
IUUC-Cel-018308	Caenorhabditis elegans	28.60	2.00e-38	153.00
IUUC-Cja-018826	Callithrix jacchus	91.89	0.00e+00	905.00
IUUC-Cfa-021206	Canis familiaris	90.19	0.00e+00	866.00
IUUC-Cpo-021343	Cavia porcellus	89.82	0.00e+00	831.00
IUUC-Csa-023419	Chlorocebus sabaeus	91.49	0.00e+00	902.00
IUUC-Cho-024475	Choloepus hoffmanni	89.09	2.00e-137	482.00
IUUC-Cgl-026621	Colletotrichum gloeosporioides	21.63	4.00e-12	67.00
IUUC-Cne-027061	Cryptococcus neoformans	25.10	1.00e-09	58.20
IUUC-Dre-027563	Danio rerio	58.91	4.00e-156	544.00
IUUC-Dno-029929	Dasypus novemcinctus	90.14	0.00e+00	879.00
IUUC-Dor-030166	Dipodomys ordii	81.43	0.00e+00	729.00
IUUC-Dme-031627	Drosophila melanogaster	33.91	4.00e-34	139.00
IUUC-Ete-032634	Echinops telfairi	79.88	0.00e+00	692.00
IUUC-Eca-033968	Equus caballus	91.43	0.00e+00	826.00
IUUC-Eeu-035279	Erinaceus europaeus	82.32	2.00e-58	220.00
IUUC-Fca-036525	Felis catus	93.04	0.00e+00	894.00
IUUC-Fal-036606	Ficedula albicollis	74.22	1.00e-159	555.00
IUUC-Gmo-038726	Gadus morhua	56.19	4.00e-144	504.00
IUUC-Gga-040718	Gallus gallus	74.56	5.00e-161	560.00
IUUC-Gac-042645	Gasterosteus aculeatus	58.06	4.00e-151	527.00
IUUC-Gma-042890	Glycine max	26.42	2.00e-25	110.00
IUUC-Ggo-045021	Gorilla gorilla	91.49	0.00e+00	899.00
IUUC-Hsa-045832	Homo sapiens	91.49	0.00e+00	899.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	91.84	0.00e+00	835.00
IUUC-Lch-050662	Latimeria chalumnae	69.70	5.00e-178	617.00
IUUC-Lpe-051078	Leersia perrieri	26.31	6.00e-31	128.00
IUUC-Loc-052611	Lepisosteus oculatus	65.69	6.00e-177	613.00
IUUC-Lma-053048	Leptosphaeria maculans	19.88	2.00e-14	74.30
IUUC-Laf-053752	Loxodonta africana	91.43	0.00e+00	825.00
IUUC-Mcc-054892	Macaca mulatta	91.88	0.00e+00	905.00
IUUC-Meu-056673	Macropus eugenii	73.11	1.00e-159	555.00
IUUC-Mtr-057976	Medicago truncatula	27.27	3.00e-32	132.00
IUUC-Mla-058970	Melampsora laricipopulina	22.04	9.00e-21	95.10
IUUC-Mga-059543	Meleagris gallopavo	74.95	0.00e+00	656.00
IUUC-Mmr-061534	Microcebus murinus	91.88	0.00e+00	874.00
IUUC-Mdo-062140	Monodelphis domestica	68.95	3.00e-164	571.00
IUUC-Mmu-063673	Mus musculus	87.62	0.00e+00	820.00
IUUC-Mpu-066328	Mustela putorius furo	91.49	0.00e+00	850.00
IUUC-Mlu-067938	Myotis lucifugus	92.65	0.00e+00	907.00
IUUC-Nle-069426	Nomascus leucogenys	90.05	0.00e+00	803.00
IUUC-Opr-070796	Ochotona princeps	83.66	2.00e-120	426.00
IUUC-Ont-072248	Oreochromis niloticus	60.71	3.00e-157	548.00
IUUC-Oan-072916	Ornithorhynchus anatinus	79.53	0.00e+00	763.00
IUUC-Ocu-074459	Oryctolagus cuniculus	84.62	0.00e+00	649.00
IUUC-Oba-075765	Oryza barthii	26.49	5.00e-29	122.00
IUUC-Obr-076005	Oryza brachyantha	27.40	6.00e-30	125.00
IUUC-Ogl-077916	Oryza glaberrima	26.26	8.00e-32	131.00
IUUC-Ogu-078263	Oryza glumaepatula	26.67	7.00e-30	125.00
IUUC-Oin-080096	Oryza indica	26.64	2.00e-23	103.00
IUUC-Ome-081928	Oryza meridionalis	26.59	4.00e-30	126.00
IUUC-Oni-082424	Oryza nivara	26.87	8.00e-30	125.00
IUUC-Oru-085117	Oryza rufipogon	26.87	8.00e-30	125.00
IUUC-Ola-087429	Oryzias latipes	57.17	4.00e-148	517.00
IUUC-Oga-087981	Otolemur garnettii	91.49	0.00e+00	865.00
IUUC-Oar-089927	Ovis aries	98.45	0.00e+00	922.00
IUUC-Ptr-090878	Pan troglodytes	91.49	0.00e+00	899.00
IUUC-Pan-092698	Papio anubis	91.88	0.00e+00	905.00
IUUC-Psi-093451	Pelodiscus sinensis	74.90	0.00e+00	699.00
IUUC-Ppa-096015	Physcomitrella patens	25.53	1.00e-09	58.90
IUUC-Pfo-096096	Poecilia formosa	58.55	2.00e-154	538.00
IUUC-Pab-098676	Pongo abelii	90.33	0.00e+00	879.00
IUUC-Pca-100418	Procavia capensis	94.25	4.00e-128	451.00
IUUC-Ppe-101898	Prunus persica	24.52	1.00e-24	107.00
IUUC-Pva-103018	Pteropus vampyrus	90.33	0.00e+00	861.00
IUUC-Pgr-103423	Puccinia graminis	26.36	2.00e-09	58.50
IUUC-Ptt-103779	Puccinia triticina	22.25	2.00e-13	71.60
IUUC-Pte-104330	Pyrenophora teres	21.57	1.00e-14	75.10
IUUC-Pyt-104518	Pyrenophora triticirepentis	22.22	2.00e-18	87.40
IUUC-Rno-105708	Rattus norvegicus	87.23	0.00e+00	813.00
IUUC-Sha-106971	Sarcophilus harrisii	77.97	0.00e+00	759.00
IUUC-Sit-110442	Setaria italica	26.36	5.00e-28	119.00
IUUC-Ssc-116397	Sus scrofa	93.62	0.00e+00	881.00
IUUC-Tgu-117446	Taeniopygia guttata	68.87	0.00e+00	633.00
IUUC-Tru-118268	Takifugu rubripes	58.63	1.00e-142	499.00
IUUC-Tsy-119484	Tarsius syrichta	87.30	1.00e-49	190.00
IUUC-Tni-119735	Tetraodon nigroviridis	55.78	5.00e-119	421.00
IUUC-Tca-121660	Theobroma cacao	25.19	3.00e-29	122.00
IUUC-Tae-125383	Triticum aestivum	27.69	7.00e-28	118.00
IUUC-Tur-126458	Triticum urartu	27.94	5.00e-26	112.00
IUUC-Tbe-127740	Tupaia belangeri	85.49	0.00e+00	778.00
IUUC-Ttr-129273	Tursiops truncatus	92.26	0.00e+00	860.00
IUUC-Vvi-131177	Vitis vinifera	25.73	2.00e-26	113.00
IUUC-Xtr-132374	Xenopus tropicalis	66.60	9.00e-170	590.00
IUUC-Xma-133267	Xiphophorus maculatus	60.28	3.00e-157	548.00
IUUC-Zma-135796	Zea mays	26.33	1.00e-24	107.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence