iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073693

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPN01210604

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000004806.2	ENSOANT00000007610.1	ENSOANP00000007608.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.80e-78	263.5	2641	3001

Active Site

Position(s)	Description	Evidence
2975	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglf.......lysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           d ++ ++++f+gEe+++++G++r+fl++++kelq+++l+l+       ++++++k+ l+p p ++     +++l +f+G+llg+a++
   Q: 2641 DPTYAFNIRFTGEEVHGTSGSFRHFLWQVCKELQSSSLSLLllcpssaVNKNKGKYILTPGPITY----GEEQLLHFFGQLLGIAIR 2723
           5667788*********************************9999999888888***********9....789*************** PP
   S: 84   dgrlldlplsksfyklllgkklsl.edleevdpelyks.lkeikenaesdieelgldltfs..vseei...............lget 151
            + +l+l+l +sf+k l+g++l+   dl e d  +y++ +k+ + n+e+++e+l+++++++  +  ++                 + 
   Q: 2724 ADVPLPLDLLSSFWKALVGEPLDPdGDLREADILTYNYvKKFENINDETELEALCAEIASQhlA--TEspdcpnkpcckftylTVTG 2808
           ************************99************44555566688999999999998532..3346999******99665556 PP
   S: 152  keeeLkpgGenipVtneNkeeYvklvveyrlke.gikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykg 237
           +e+eL+++G+ i V +eNk+ Y  ++ ++rl+e + + +++a+r+G+ ++ipl+ll+++t++e+el +cG ++i++e lk++t+y+ 
   Q: 2809 EEVELCSRGRLIAVGWENKDVYAAAIRSLRLRElQNQDCMTAVRAGLASIIPLQLLTMLTPREMELRTCGLPYINLEFLKAHTMYQV 2895
           6777*****************************9***************************************************** PP
   S: 238  gytedspaiqwFwevleefsseerkafLqFvTgssrlPl......gGfaelk....prlfvirk...dasddrlPssnTCfnyLkLP 311
           g++e++++i++Fw +le+f++ee ++f++F+++++r+P+      gG ++ +    p+++  ++    + d+r+++++TC++++kLP
   Q: 2896 GLMETDQHIEFFWGALEMFTQEELCKFIKFACNQERIPFtcpckdGGPDTAHvppyPMKIAPPDgaaGSPDSRYIRVETCMFMIKLP 2982
           *********************************************9999999998888888888*955555**************** PP
   S: 312  eYsskeilkekLlyAieet 330
           +Yss e++ ekL+ Ai+++
   Q: 2983 QYSSLETMLEKLRSAIHYR 3001
           ****************986 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

NKMKELELLC SMKEVSFDGS DLENMVLSLR EKFLQEVNSL IQKPSHPMAK TKTLVKSLMN 60
RAELLLHVTI AAQSSLTRSI SGTPAETPAC KSASETKVIS PVVRQPVFLR SMSAPSDLEM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACAAAATGA AAGAATTAGA ACTTTTATGT TCAATGAAGG AAGTCTCCTT TGATGGAAGT 60
GATCTTGAGA ATATGGTCCT GTCACTGAGG TTAGTAATGT TCAAAAAAGG AAAAGAAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002256	Ailuropoda melanoleuca	95.05	0.00e+00	3405.00
IUUC-Apl-004161	Anas platyrhynchos	92.63	0.00e+00	5237.00
IUUC-Aca-005341	Anolis carolinensis	90.64	0.00e+00	5081.00
IUUC-Ame-011574	Astyanax mexicanus	83.61	0.00e+00	3042.00
IUUC-Bta-012514	Bos taurus	89.18	0.00e+00	1825.00
IUUC-Cja-019148	Callithrix jacchus	92.83	0.00e+00	5097.00
IUUC-Cfa-020499	Canis familiaris	95.10	0.00e+00	3429.00
IUUC-Cpo-021894	Cavia porcellus	94.63	0.00e+00	2724.00
IUUC-Csa-023079	Chlorocebus sabaeus	92.82	0.00e+00	5144.00
IUUC-Cho-024415	Choloepus hoffmanni	91.56	0.00e+00	3237.00
IUUC-Dre-027452	Danio rerio	81.62	0.00e+00	3054.00
IUUC-Dno-029595	Dasypus novemcinctus	92.27	0.00e+00	5185.00
IUUC-Dor-030849	Dipodomys ordii	89.15	0.00e+00	1456.00
IUUC-Ete-032563	Echinops telfairi	87.12	0.00e+00	1129.00
IUUC-Eca-034202	Equus caballus	95.27	0.00e+00	3402.00
IUUC-Eeu-035175	Erinaceus europaeus	91.86	0.00e+00	1028.00
IUUC-Fca-036295	Felis catus	92.05	0.00e+00	5180.00
IUUC-Fal-037003	Ficedula albicollis	92.61	0.00e+00	4435.00
IUUC-Gmo-038579	Gadus morhua	84.35	0.00e+00	2864.00
IUUC-Gga-040961	Gallus gallus	92.29	0.00e+00	5224.00
IUUC-Gac-041899	Gasterosteus aculeatus	84.94	0.00e+00	2922.00
IUUC-Ggo-045099	Gorilla gorilla	93.58	0.00e+00	5216.00
IUUC-Hsa-046331	Homo sapiens	92.92	0.00e+00	5194.00
IUUC-Itr-048190	Ictidomys tridecemlineatus	91.53	0.00e+00	1781.00
IUUC-Lch-049923	Latimeria chalumnae	90.51	0.00e+00	1171.00
IUUC-Loc-052630	Lepisosteus oculatus	84.22	0.00e+00	4082.00
IUUC-Laf-053394	Loxodonta africana	94.73	0.00e+00	3408.00
IUUC-Mcc-055763	Macaca mulatta	92.85	0.00e+00	5141.00
IUUC-Meu-056039	Macropus eugenii	88.50	0.00e+00	4900.00
IUUC-Mga-059500	Meleagris gallopavo	92.10	0.00e+00	5202.00
IUUC-Mmr-060868	Microcebus murinus	87.75	0.00e+00	4883.00
IUUC-Mdo-062772	Monodelphis domestica	93.15	0.00e+00	5256.00
IUUC-Mmu-063606	Mus musculus	93.87	0.00e+00	3398.00
IUUC-Mpu-065860	Mustela putorius furo	92.69	0.00e+00	3318.00
IUUC-Mlu-067376	Myotis lucifugus	94.41	0.00e+00	3397.00
IUUC-Nle-069693	Nomascus leucogenys	91.01	0.00e+00	5060.00
IUUC-Ont-072470	Oreochromis niloticus	83.92	0.00e+00	3076.00
IUUC-Ocu-074032	Oryctolagus cuniculus	91.52	0.00e+00	5118.00
IUUC-Ola-087433	Oryzias latipes	83.57	0.00e+00	1461.00
IUUC-Oga-088546	Otolemur garnettii	94.89	0.00e+00	3398.00
IUUC-Oar-089643	Ovis aries	86.49	0.00e+00	726.00
IUUC-Ptr-090504	Pan troglodytes	92.92	0.00e+00	5197.00
IUUC-Pan-092543	Papio anubis	92.82	0.00e+00	5146.00
IUUC-Psi-093952	Pelodiscus sinensis	91.04	0.00e+00	5132.00
IUUC-Pfo-096356	Poecilia formosa	84.40	0.00e+00	3069.00
IUUC-Pab-098240	Pongo abelii	92.75	0.00e+00	5139.00
IUUC-Pca-100994	Procavia capensis	96.48	0.00e+00	1673.00
IUUC-Pva-102263	Pteropus vampyrus	93.23	0.00e+00	3313.00
IUUC-Rno-104888	Rattus norvegicus	94.19	0.00e+00	3380.00
IUUC-Sha-106944	Sarcophilus harrisii	92.20	0.00e+00	5255.00
IUUC-Sar-113556	Sorex araneus	82.82	0.00e+00	930.00
IUUC-Ssc-116187	Sus scrofa	92.74	0.00e+00	4996.00
IUUC-Tgu-116655	Taeniopygia guttata	91.50	0.00e+00	5172.00
IUUC-Tru-118093	Takifugu rubripes	82.97	0.00e+00	3013.00
IUUC-Tni-119739	Tetraodon nigroviridis	83.39	0.00e+00	1469.00
IUUC-Tbe-127962	Tupaia belangeri	83.56	0.00e+00	1135.00
IUUC-Ttr-128819	Tursiops truncatus	86.77	0.00e+00	2729.00
IUUC-Vpa-130482	Vicugna pacos	93.48	0.00e+00	2596.00
IUUC-Xtr-132222	Xenopus tropicalis	90.35	0.00e+00	3282.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence