iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066009

Ensembl Protein ID

ENSMPUP00000009885.1

UniProt Accession

M3YEX8; M3YEX8_MUSPF

Genbank Protein ID

ENSMPUP00000009885

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01093350

Gene Name

CDC34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000009960.1	ENSMPUT00000010045.1	ENSMPUP00000009885.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.10e-48	162.7	15	153

Active Site

Position(s)	Description	Evidence
93	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 4    kelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk..... 87
            elk l+++p+eg+++++vde dl++wev+i+Gp++t+Yegg+Fk++++fp dYP++PP ++fltk++hPn+ye+G+vC+sil+     
   Q: 15   LELKGLQEEPVEGFRVTLVDEGDLYNWEVAIFGPPNTYYEGGYFKARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHppvdd 103
           599********************************************************************************999999 PP
   S: 88   ......eeekWspalsvesvllsiqsllaepnpesplneeaaellkknre 131
                 ++e+W+p+++v+++lls++sll+epn+ sp+n++a+ +++k++e
   Q: 104  pqsgelPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKE 153
           999*9******************************************998 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MARPLVPSSQ KALLLELKGL QEEPVEGFRV TLVDEGDLYN WEVAIFGPPN TYYEGGYFKA 60
RLKFPIDYPY SPPAFRFLTK MWHPNIYETG DVCISILHPP VDDPQSGELP SERWNPTQNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 60
NNNNNCGCCG CCATGGCCCG GCCGCTGGTG CCCAGCTCGC AGAAGGCGCT GCTGCTCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005829--C:cytosol
GO:0016607--C:nuclear speck
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0035458--P:cellular response to interferon-beta
GO:0043951--P:negative regulation of cAMP-mediated signaling
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001600	Ailuropoda melanoleuca	100.00	3.00e-132	463.00
IUUC-Aca-004589	Anolis carolinensis	85.22	1.00e-104	371.00
IUUC-Ate-010563	Aspergillus terreus	42.04	4.00e-36	144.00
IUUC-Ame-011425	Astyanax mexicanus	89.55	2.00e-108	384.00
IUUC-Bta-012516	Bos taurus	99.51	2.00e-120	424.00
IUUC-Cel-018460	Caenorhabditis elegans	65.78	1.00e-71	262.00
IUUC-Cja-018852	Callithrix jacchus	89.91	5.00e-104	370.00
IUUC-Cfa-020203	Canis familiaris	99.55	5.00e-121	426.00
IUUC-Cpo-022139	Cavia porcellus	91.23	1.00e-120	425.00
IUUC-Csa-023371	Chlorocebus sabaeus	98.66	2.00e-122	431.00
IUUC-Cho-024999	Choloepus hoffmanni	73.33	1.00e-23	102.00
IUUC-Cin-025257	Ciona intestinalis	68.91	1.00e-81	295.00
IUUC-Csv-025954	Ciona savignyi	67.35	3.00e-82	297.00
IUUC-Dre-028367	Danio rerio	89.05	4.00e-108	383.00
IUUC-Dno-029368	Dasypus novemcinctus	86.32	3.00e-99	353.00
IUUC-Dor-030875	Dipodomys ordii	99.11	4.00e-123	433.00
IUUC-Dme-032106	Drosophila melanogaster	71.79	6.00e-85	307.00
IUUC-Fca-035832	Felis catus	99.40	2.00e-96	343.00
IUUC-Fal-037135	Ficedula albicollis	85.22	8.00e-102	362.00
IUUC-Gmo-039414	Gadus morhua	90.05	2.00e-109	387.00
IUUC-Gga-040694	Gallus gallus	96.19	2.00e-123	434.00
IUUC-Gac-042485	Gasterosteus aculeatus	88.56	5.00e-109	386.00
IUUC-Ggo-044806	Gorilla gorilla	99.11	1.00e-122	432.00
IUUC-Hsa-046245	Homo sapiens	99.11	2.00e-122	431.00
IUUC-Itr-047928	Ictidomys tridecemlineatus	97.97	3.00e-84	303.00
IUUC-Lch-049845	Latimeria chalumnae	90.05	2.00e-109	387.00
IUUC-Loc-052932	Lepisosteus oculatus	91.54	5.00e-111	393.00
IUUC-Laf-053860	Loxodonta africana	84.73	6.00e-104	369.00
IUUC-Mcc-054665	Macaca mulatta	95.09	2.00e-115	407.00
IUUC-Meu-056681	Macropus eugenii	79.80	2.00e-97	348.00
IUUC-Mga-060075	Meleagris gallopavo	95.76	3.00e-123	433.00
IUUC-Mmr-061165	Microcebus murinus	98.21	3.00e-121	427.00
IUUC-Mdo-061825	Monodelphis domestica	97.77	4.00e-120	423.00
IUUC-Mmu-064168	Mus musculus	100.00	2.00e-120	424.00
IUUC-Mlu-067397	Myotis lucifugus	82.74	1.00e-97	348.00
IUUC-Opr-070826	Ochotona princeps	93.49	3.00e-109	387.00
IUUC-Ont-071745	Oreochromis niloticus	90.15	1.00e-110	391.00
IUUC-Oan-073287	Ornithorhynchus anatinus	91.10	8.00e-119	419.00
IUUC-Ocu-074902	Oryctolagus cuniculus	95.63	3.00e-116	410.00
IUUC-Ola-086976	Oryzias latipes	89.39	6.00e-108	383.00
IUUC-Oga-088845	Otolemur garnettii	97.32	4.00e-126	443.00
IUUC-Oar-089383	Ovis aries	84.73	6.00e-104	369.00
IUUC-Ptr-090916	Pan troglodytes	99.03	1.00e-117	414.00
IUUC-Pan-092577	Papio anubis	98.66	2.00e-122	431.00
IUUC-Psi-093039	Pelodiscus sinensis	94.38	7.00e-89	319.00
IUUC-Pfo-096435	Poecilia formosa	89.55	1.00e-109	388.00
IUUC-Pab-098200	Pongo abelii	99.02	2.00e-111	394.00
IUUC-Pca-100169	Procavia capensis	86.43	8.00e-66	242.00
IUUC-Pva-102875	Pteropus vampyrus	99.39	2.00e-85	307.00
IUUC-Rno-106079	Rattus norvegicus	100.00	2.00e-120	424.00
IUUC-Sha-107364	Sarcophilus harrisii	85.22	1.00e-104	372.00
IUUC-Sar-112992	Sorex araneus	81.37	2.00e-95	341.00
IUUC-Ssc-115699	Sus scrofa	90.91	3.00e-88	317.00
IUUC-Tgu-117466	Taeniopygia guttata	94.07	3.00e-121	427.00
IUUC-Tru-117589	Takifugu rubripes	84.39	2.00e-103	368.00
IUUC-Tni-120864	Tetraodon nigroviridis	86.07	3.00e-105	374.00
IUUC-Tbe-128014	Tupaia belangeri	84.73	6.00e-104	369.00
IUUC-Ttr-129037	Tursiops truncatus	86.26	3.00e-95	340.00
IUUC-Xtr-132285	Xenopus tropicalis	89.50	2.00e-117	414.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence