iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005039

UUCD1 version

UUC-AnC-00193

Ensembl Protein ID

ENSACAP00000001230.2

UniProt Accession

H9G4Y4; H9G4Y4_ANOCA

Protein Name

Uncharacterized protein

Gene Name

MUL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000001340.2	ENSACAT00000001263.2	ENSACAP00000001230.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	37.79	3.00e-62	236.00	IUUC-Hsa-046597

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

TAGELVCLGS SLAFSGLFYY LHRKKAKVVA RIQDAPKLQV SASLPSILSA TDSSCLDYVV 60
IEGVVQPADA PLTSPYHREL QGVIERLMLK EHRLIWNSLA RSWTDSERVV LEQVHTVPFV 120

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Nucleotide Sequence
(Fasta)

ACCGCAGGAG AGCTAGTGTG CTTGGGCTCC AGCCTTGCCT TCTCAGGTCT CTTTTATTAC 60
CTGCACAGGA AGAAGGCCAA GGTGGTGGCC AGAATCCAGG TATTTGTTTG TGCCTCTTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR022170--GIDE
IPR001841--Znf_RING

PROSITE

PS50089--ZF_RING_2

Pfam

PF12483--GIDE

SMART

SM00184--RING

Gene Ontology

GO:0030424--C:axon
GO:0031307--C:integral component of mitochondrial outer membrane
GO:0043025--C:neuronal cell body
GO:0005777--C:peroxisome
GO:0004871--F:signal transducer activity
GO:0019789--F:SUMO transferase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007257--P:activation of JUN kinase activity
GO:0071360--P:cellular response to exogenous dsRNA
GO:0000266--P:mitochondrial fission
GO:0051646--P:mitochondrion localization
GO:0030308--P:negative regulation of cell growth
GO:0071650--P:negative regulation of chemokine (C-C motif) ligand 5 production
GO:0050689--P:negative regulation of defense response to virus by host
GO:0010637--P:negative regulation of mitochondrial fusion
GO:0051898--P:negative regulation of protein kinase B signaling
GO:0060339--P:negative regulation of type I interferon-mediated signaling pathway
GO:1903861--P:positive regulation of dendrite extension
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0090141--P:positive regulation of mitochondrial fission
GO:1904925--P:positive regulation of mitophagy in response to mitochondrial depolarization
GO:0033235--P:positive regulation of protein sumoylation
GO:0031648--P:protein destabilization
GO:0050821--P:protein stabilization
GO:0051881--P:regulation of mitochondrial membrane potential
GO:1901028--P:regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002287	Ailuropoda melanoleuca	39.19	5.00e-67	247.00
IUUC-Atr-002698	Amborella trichopoda	25.71	7.00e-15	74.70
IUUC-Aly-006181	Arabidopsis lyrata	23.96	7.00e-16	77.80
IUUC-Ath-007438	Arabidopsis thaliana	23.67	6.00e-16	78.20
IUUC-Ame-010671	Astyanax mexicanus	40.36	7.00e-64	237.00
IUUC-Bta-012407	Bos taurus	40.52	4.00e-65	241.00
IUUC-Bdi-014735	Brachypodium distachyon	27.14	3.00e-13	69.30
IUUC-Bol-015493	Brassica oleracea	24.04	2.00e-18	86.30
IUUC-Bra-016933	Brassica rapa	24.25	3.00e-17	82.00
IUUC-Cja-019709	Callithrix jacchus	40.25	4.00e-63	234.00
IUUC-Cfa-020818	Canis familiaris	39.77	6.00e-68	250.00
IUUC-Cpo-022490	Cavia porcellus	38.68	1.00e-65	243.00
IUUC-Csa-023259	Chlorocebus sabaeus	39.53	7.00e-67	247.00
IUUC-Cho-024730	Choloepus hoffmanni	41.45	4.00e-68	251.00
IUUC-Cin-025301	Ciona intestinalis	29.08	3.00e-34	138.00
IUUC-Cgl-026563	Colletotrichum gloeosporioides	40.68	3.00e-04	37.70
IUUC-Dre-028644	Danio rerio	38.86	2.00e-61	229.00
IUUC-Dno-028925	Dasypus novemcinctus	40.87	6.00e-69	254.00
IUUC-Dor-030692	Dipodomys ordii	41.33	2.00e-68	252.00
IUUC-Dme-031761	Drosophila melanogaster	28.95	6.00e-23	101.00
IUUC-Ete-032329	Echinops telfairi	36.05	4.00e-54	204.00
IUUC-Eca-034008	Equus caballus	39.48	2.00e-67	249.00
IUUC-Eeu-034895	Erinaceus europaeus	41.87	9.00e-41	160.00
IUUC-Fca-036104	Felis catus	39.77	1.00e-67	249.00
IUUC-Fal-036900	Ficedula albicollis	41.81	3.00e-67	248.00
IUUC-Gmo-039049	Gadus morhua	40.58	8.00e-58	217.00
IUUC-Gga-040254	Gallus gallus	41.83	3.00e-61	228.00
IUUC-Gac-042277	Gasterosteus aculeatus	39.48	5.00e-69	254.00
IUUC-Gma-043979	Glycine max	26.44	2.00e-18	85.90
IUUC-Ggo-045509	Gorilla gorilla	39.53	7.00e-67	247.00
IUUC-Hsa-046597	Homo sapiens	39.53	7.00e-67	247.00
IUUC-Hvu-047335	Hordeum vulgare	27.34	3.00e-16	78.60
IUUC-Itr-048691	Ictidomys tridecemlineatus	40.00	2.00e-65	242.00
IUUC-Lch-050344	Latimeria chalumnae	40.41	3.00e-69	255.00
IUUC-Loc-052376	Lepisosteus oculatus	41.67	2.00e-72	265.00
IUUC-Laf-054414	Loxodonta africana	40.87	1.00e-67	249.00
IUUC-Mcc-054604	Macaca mulatta	39.53	7.00e-67	247.00
IUUC-Meu-056087	Macropus eugenii	42.07	1.00e-66	246.00
IUUC-Mtr-057779	Medicago truncatula	25.68	6.00e-16	77.80
IUUC-Mga-060188	Meleagris gallopavo	41.72	3.00e-63	234.00
IUUC-Mmr-060704	Microcebus murinus	40.58	1.00e-68	253.00
IUUC-Mdo-062842	Monodelphis domestica	40.69	7.00e-64	237.00
IUUC-Mmu-064324	Mus musculus	40.58	5.00e-64	237.00
IUUC-Mpu-065940	Mustela putorius furo	39.48	7.00e-63	233.00
IUUC-Mlu-067028	Myotis lucifugus	40.29	3.00e-69	254.00
IUUC-Nle-069254	Nomascus leucogenys	36.99	4.00e-60	224.00
IUUC-Opr-070827	Ochotona princeps	40.29	6.00e-68	250.00
IUUC-Ont-072008	Oreochromis niloticus	39.48	1.00e-69	256.00
IUUC-Oan-072935	Ornithorhynchus anatinus	41.79	2.00e-72	265.00
IUUC-Ocu-074526	Oryctolagus cuniculus	39.77	2.00e-66	245.00
IUUC-Obr-076592	Oryza brachyantha	26.55	7.00e-18	84.30
IUUC-Ogl-077732	Oryza glaberrima	26.84	5.00e-18	84.70
IUUC-Oin-080188	Oryza indica	26.84	5.00e-18	84.70
IUUC-Olo-080705	Oryza longistaminata	27.03	1.00e-16	80.90
IUUC-Ola-087288	Oryzias latipes	38.90	6.00e-63	234.00
IUUC-Oga-088402	Otolemur garnettii	40.46	4.00e-68	251.00
IUUC-Oar-089851	Ovis aries	38.46	2.00e-29	121.00
IUUC-Ptr-091226	Pan troglodytes	39.53	1.00e-66	246.00
IUUC-Pan-092575	Papio anubis	39.53	6.00e-67	247.00
IUUC-Psi-094062	Pelodiscus sinensis	41.50	2.00e-70	259.00
IUUC-Pma-094501	Petromyzon marinus	35.27	8.00e-31	127.00
IUUC-Ppa-095285	Physcomitrella patens	23.40	9.00e-07	47.80
IUUC-Pfo-096146	Poecilia formosa	38.22	5.00e-59	221.00
IUUC-Pab-098524	Pongo abelii	39.53	6.00e-67	247.00
IUUC-Pop-099864	Populus trichocarpa	28.57	1.00e-18	87.00
IUUC-Pca-100314	Procavia capensis	39.88	5.00e-67	247.00
IUUC-Ppe-101663	Prunus persica	25.33	1.00e-17	83.60
IUUC-Pva-102947	Pteropus vampyrus	39.13	3.00e-66	244.00
IUUC-Rno-105024	Rattus norvegicus	40.75	9.00e-67	246.00
IUUC-Sha-107500	Sarcophilus harrisii	41.21	3.00e-41	161.00
IUUC-Smo-109194	Selaginella moellendorffii	25.14	2.00e-19	89.70
IUUC-Sit-109922	Setaria italica	25.96	3.00e-15	75.90
IUUC-Sly-111826	Solanum lycopersicum	26.65	1.00e-18	87.40
IUUC-Stu-112907	Solanum tuberosum	28.00	2.00e-18	86.30
IUUC-Sar-113522	Sorex araneus	40.76	2.00e-59	221.00
IUUC-Sbi-114536	Sorghum bicolor	25.96	3.00e-18	85.50
IUUC-Ssc-115445	Sus scrofa	38.84	2.00e-65	242.00
IUUC-Tgu-116551	Taeniopygia guttata	40.43	7.00e-64	237.00
IUUC-Tru-118407	Takifugu rubripes	39.70	2.00e-59	222.00
IUUC-Tsy-118794	Tarsius syrichta	40.58	6.00e-66	244.00
IUUC-Tni-120128	Tetraodon nigroviridis	41.33	3.00e-46	178.00
IUUC-Tca-121508	Theobroma cacao	24.21	3.00e-17	82.40
IUUC-Tae-125185	Triticum aestivum	26.30	2.00e-17	83.20
IUUC-Tur-126470	Triticum urartu	26.01	2.00e-17	82.80
IUUC-Tbe-127432	Tupaia belangeri	39.48	2.00e-64	239.00
IUUC-Ttr-128573	Tursiops truncatus	41.45	7.00e-69	253.00
IUUC-Vpa-130583	Vicugna pacos	40.95	2.00e-61	229.00
IUUC-Vvi-131710	Vitis vinifera	25.75	8.00e-17	80.90
IUUC-Xtr-132009	Xenopus tropicalis	40.52	4.00e-68	251.00
IUUC-Xma-134121	Xiphophorus maculatus	38.62	7.00e-65	240.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence