iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062842

UUCD1 version

UUC-MoD-00908

Ensembl Protein ID

ENSMODP00000019910.3

UniProt Accession

F7FRJ4; F7FRJ4_MONDO

Protein Name

Uncharacterized protein

Gene Name

MUL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000015955.3	ENSMODT00000020266.3	ENSMODP00000019910.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	85.23	2.00e-165	579.00	IUUC-Hsa-046597

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MDSGGRPSAI QLILLGTSSA VAAALYSVYR HKAQAARELK GAKKIHLGED LKSILIDAPG 60
KCVPYAVIEG AVRSVKETLN SQFVENCKGV IQRLTLQEHK MVWNRTTHLW NDCEKIIHQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGTCTCCCT TTCCGGGTTT CTCACCCTTC CGGTTTCACC TCTTCCGGCC TCTCTGGCTG 60
CCTCGGTGGC TGTGCGTCTC TATGGTTCCG GCGCGGGCTA GGGGCGGCGG CGGCGGCGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR022170--GIDE
IPR001841--Znf_RING

PROSITE

PS50089--ZF_RING_2

Pfam

PF12483--GIDE

SMART

SM00184--RING

Gene Ontology

GO:0030424--C:axon
GO:0031307--C:integral component of mitochondrial outer membrane
GO:0043025--C:neuronal cell body
GO:0005777--C:peroxisome
GO:0004871--F:signal transducer activity
GO:0019789--F:SUMO transferase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007257--P:activation of JUN kinase activity
GO:0071360--P:cellular response to exogenous dsRNA
GO:0000266--P:mitochondrial fission
GO:0051646--P:mitochondrion localization
GO:0030308--P:negative regulation of cell growth
GO:0071650--P:negative regulation of chemokine (C-C motif) ligand 5 production
GO:0050689--P:negative regulation of defense response to virus by host
GO:0010637--P:negative regulation of mitochondrial fusion
GO:0051898--P:negative regulation of protein kinase B signaling
GO:0060339--P:negative regulation of type I interferon-mediated signaling pathway
GO:1903861--P:positive regulation of dendrite extension
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0090141--P:positive regulation of mitochondrial fission
GO:1904925--P:positive regulation of mitophagy in response to mitochondrial depolarization
GO:0033235--P:positive regulation of protein sumoylation
GO:0031648--P:protein destabilization
GO:0050821--P:protein stabilization
GO:0051881--P:regulation of mitochondrial membrane potential
GO:1901028--P:regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

KEGG

mdo:100023555

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002287	Ailuropoda melanoleuca	83.52	3.00e-174	603.00
IUUC-Atr-002698	Amborella trichopoda	25.00	9.00e-11	61.20
IUUC-Aca-005039	Anolis carolinensis	42.36	8.00e-67	247.00
IUUC-Aly-006181	Arabidopsis lyrata	27.33	4.00e-21	95.50
IUUC-Ath-007438	Arabidopsis thaliana	28.03	3.00e-21	95.90
IUUC-Ame-010671	Astyanax mexicanus	62.78	7.00e-135	473.00
IUUC-Bta-012407	Bos taurus	75.92	2.00e-157	548.00
IUUC-Bdi-014735	Brachypodium distachyon	24.49	1.00e-18	87.00
IUUC-Bol-015493	Brassica oleracea	27.07	1.00e-23	103.00
IUUC-Bra-016933	Brassica rapa	27.43	6.00e-21	94.70
IUUC-Cja-019709	Callithrix jacchus	85.36	3.00e-171	593.00
IUUC-Cfa-020818	Canis familiaris	84.66	4.00e-179	620.00
IUUC-Cpo-022490	Cavia porcellus	83.24	2.00e-169	588.00
IUUC-Csa-023259	Chlorocebus sabaeus	85.23	0.00e+00	644.00
IUUC-Cho-024730	Choloepus hoffmanni	84.94	0.00e+00	636.00
IUUC-Cin-025301	Ciona intestinalis	31.83	1.00e-46	180.00
IUUC-Dre-028644	Danio rerio	62.78	1.00e-135	475.00
IUUC-Dno-028925	Dasypus novemcinctus	82.67	0.00e+00	628.00
IUUC-Dor-030692	Dipodomys ordii	84.09	9.00e-175	605.00
IUUC-Dme-031761	Drosophila melanogaster	31.93	5.00e-34	138.00
IUUC-Ete-032329	Echinops telfairi	76.14	6.00e-148	516.00
IUUC-Eca-034008	Equus caballus	80.68	2.00e-177	615.00
IUUC-Eeu-034895	Erinaceus europaeus	70.83	1.00e-113	402.00
IUUC-Fca-036104	Felis catus	82.95	2.00e-177	614.00
IUUC-Fal-036900	Ficedula albicollis	75.29	1.00e-142	499.00
IUUC-Gmo-039049	Gadus morhua	59.38	5.00e-110	390.00
IUUC-Gga-040254	Gallus gallus	73.58	1.00e-152	532.00
IUUC-Gac-042277	Gasterosteus aculeatus	61.36	2.00e-137	481.00
IUUC-Gma-043979	Glycine max	25.98	1.00e-18	87.40
IUUC-Ggo-045509	Gorilla gorilla	85.23	0.00e+00	644.00
IUUC-Hsa-046597	Homo sapiens	85.23	0.00e+00	644.00
IUUC-Hvu-047335	Hordeum vulgare	26.64	9.00e-20	90.50
IUUC-Itr-048691	Ictidomys tridecemlineatus	84.66	6.00e-175	606.00
IUUC-Lch-050344	Latimeria chalumnae	69.60	1.00e-147	515.00
IUUC-Loc-052376	Lepisosteus oculatus	68.75	5.00e-156	543.00
IUUC-Laf-054414	Loxodonta africana	85.80	0.00e+00	642.00
IUUC-Mcc-054604	Macaca mulatta	84.94	0.00e+00	643.00
IUUC-Meu-056087	Macropus eugenii	96.02	0.00e+00	647.00
IUUC-Mtr-057779	Medicago truncatula	26.53	6.00e-20	91.30
IUUC-Mga-060188	Meleagris gallopavo	76.92	1.00e-152	532.00
IUUC-Mmr-060704	Microcebus murinus	85.80	0.00e+00	641.00
IUUC-Mmu-064324	Mus musculus	82.39	2.00e-168	585.00
IUUC-Mpu-065940	Mustela putorius furo	80.97	1.00e-167	582.00
IUUC-Mlu-067028	Myotis lucifugus	83.81	0.00e+00	635.00
IUUC-Nle-069254	Nomascus leucogenys	77.97	2.00e-169	588.00
IUUC-Opr-070827	Ochotona princeps	80.97	3.00e-177	614.00
IUUC-Ont-072008	Oreochromis niloticus	63.35	1.00e-141	495.00
IUUC-Oan-072935	Ornithorhynchus anatinus	80.68	2.00e-170	591.00
IUUC-Ocu-074526	Oryctolagus cuniculus	84.38	5.00e-172	597.00
IUUC-Obr-076592	Oryza brachyantha	27.70	4.00e-26	112.00
IUUC-Ogl-077732	Oryza glaberrima	27.41	9.00e-26	110.00
IUUC-Oin-080188	Oryza indica	27.41	9.00e-26	110.00
IUUC-Olo-080705	Oryza longistaminata	28.39	6.00e-18	85.50
IUUC-Ola-087288	Oryzias latipes	59.94	1.00e-131	462.00
IUUC-Oga-088402	Otolemur garnettii	84.66	0.00e+00	639.00
IUUC-Oar-089851	Ovis aries	87.65	6.00e-84	302.00
IUUC-Ptr-091226	Pan troglodytes	84.94	0.00e+00	643.00
IUUC-Pan-092575	Papio anubis	84.66	0.00e+00	642.00
IUUC-Psi-094062	Pelodiscus sinensis	78.12	3.00e-168	583.00
IUUC-Pma-094501	Petromyzon marinus	37.15	1.00e-47	183.00
IUUC-Ppa-095285	Physcomitrella patens	24.84	6.00e-16	78.20
IUUC-Pfo-096146	Poecilia formosa	57.67	1.00e-123	436.00
IUUC-Pab-098524	Pongo abelii	85.23	0.00e+00	644.00
IUUC-Pop-099864	Populus trichocarpa	26.40	4.00e-19	89.00
IUUC-Pca-100314	Procavia capensis	84.38	0.00e+00	639.00
IUUC-Ppe-101663	Prunus persica	24.85	5.00e-17	81.60
IUUC-Pva-102947	Pteropus vampyrus	83.52	0.00e+00	629.00
IUUC-Rno-105024	Rattus norvegicus	81.53	6.00e-170	589.00
IUUC-Sha-107500	Sarcophilus harrisii	79.05	5.00e-134	470.00
IUUC-Smo-109194	Selaginella moellendorffii	26.82	2.00e-21	96.70
IUUC-Sit-109922	Setaria italica	27.99	6.00e-23	101.00
IUUC-Sly-111826	Solanum lycopersicum	25.75	1.00e-20	94.00
IUUC-Stu-112907	Solanum tuberosum	25.67	2.00e-20	93.20
IUUC-Sar-113522	Sorex araneus	82.69	1.00e-157	548.00
IUUC-Sbi-114536	Sorghum bicolor	27.70	1.00e-26	113.00
IUUC-Ssc-115445	Sus scrofa	84.66	1.00e-172	598.00
IUUC-Tgu-116551	Taeniopygia guttata	72.44	3.00e-137	481.00
IUUC-Tru-118407	Takifugu rubripes	58.52	5.00e-119	420.00
IUUC-Tsy-118794	Tarsius syrichta	82.39	3.00e-178	617.00
IUUC-Tni-120128	Tetraodon nigroviridis	65.25	4.00e-95	340.00
IUUC-Tca-121508	Theobroma cacao	27.70	8.00e-22	97.80
IUUC-Tae-125185	Triticum aestivum	27.27	5.00e-24	104.00
IUUC-Tur-126470	Triticum urartu	26.98	8.00e-24	104.00
IUUC-Tbe-127432	Tupaia belangeri	83.81	1.00e-169	588.00
IUUC-Ttr-128573	Tursiops truncatus	82.67	3.00e-175	607.00
IUUC-Vpa-130583	Vicugna pacos	85.58	7.00e-166	575.00
IUUC-Vvi-131710	Vitis vinifera	25.27	5.00e-17	81.60
IUUC-Xtr-132009	Xenopus tropicalis	62.71	3.00e-138	484.00
IUUC-Xma-134121	Xiphophorus maculatus	57.67	1.00e-128	452.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence