iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-021362

Ensembl Protein ID

ENSCPOP00000005767.2

UniProt Accession

H0V7P7; H0V7P7_CAVPO

Genbank Protein ID

ENSCPOP00000005767

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02035668

Gene Name

HCLS1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000006399.3	ENSCPOT00000006464.2	ENSCPOP00000005767.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	7.80e-13	48.2	420	471

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
            +lydy+++ +deL++   d+++ i  e  degW++g  + +g  GlfP+n+v+ l
   Q: 420  VTLYDYQGEGSDELSFDPDDIITDI--EMVDEGWWRG--QCRGHFGLFPANYVKLL 471
           69**********************9..9*********..7*************977 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MWKSVVGHDV SVSVETQGDD WDTDPDFVND ISEKEQRWGA KTIEGSGHTE HINIHQLRSK 60
VSEEHDVLKK KEMESGPKAS HGYGGRFGVE RDRMDKSAVG HEYVAEVGKH SSQTDAAKGF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGGAAGT CAGTGGTGGG CCATGATGTG TCTGTTTCTG TGGAGACACA GGGTGATGAC 60
TGGGACACAG ACCCTGACTT TGTGGTAAGT TTGGAAGTAG CTTTGCTTGG ACAATGAGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028534--HS1
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005667--C:transcription factor complex
GO:0030041--P:actin filament polymerization
GO:0071345--P:cellular response to cytokine stimulus
GO:0030218--P:erythrocyte differentiation
GO:2000107--P:negative regulation of leukocyte apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0008284--P:positive regulation of cell proliferation
GO:0030854--P:positive regulation of granulocyte differentiation
GO:0045651--P:positive regulation of macrophage differentiation
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0014068--P:positive regulation of phosphatidylinositol 3-kinase signaling
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0042531--P:positive regulation of tyrosine phosphorylation of STAT protein
GO:0030833--P:regulation of actin filament polymerization
GO:0009725--P:response to hormone

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001194	Ailuropoda melanoleuca	82.16	0.00e+00	663.00
IUUC-Bta-012591	Bos taurus	83.30	0.00e+00	630.00
IUUC-Cja-019982	Callithrix jacchus	84.73	0.00e+00	649.00
IUUC-Cfa-020262	Canis familiaris	79.92	2.00e-172	598.00
IUUC-Csa-023911	Chlorocebus sabaeus	83.40	0.00e+00	643.00
IUUC-Dor-030437	Dipodomys ordii	74.48	8.00e-164	570.00
IUUC-Ete-033160	Echinops telfairi	71.90	7.00e-140	490.00
IUUC-Eca-033269	Equus caballus	80.78	0.00e+00	648.00
IUUC-Eeu-035032	Erinaceus europaeus	71.77	2.00e-109	389.00
IUUC-Fca-035999	Felis catus	77.76	0.00e+00	673.00
IUUC-Fal-037107	Ficedula albicollis	65.49	6.00e-106	377.00
IUUC-Gga-040335	Gallus gallus	68.55	3.00e-107	382.00
IUUC-Ggo-044505	Gorilla gorilla	80.58	0.00e+00	631.00
IUUC-Hsa-046728	Homo sapiens	88.10	1.00e-152	532.00
IUUC-Itr-048592	Ictidomys tridecemlineatus	68.26	9.00e-161	560.00
IUUC-Laf-054202	Loxodonta africana	83.78	0.00e+00	639.00
IUUC-Mcc-055824	Macaca mulatta	83.16	0.00e+00	639.00
IUUC-Mmr-061281	Microcebus murinus	74.22	2.00e-160	558.00
IUUC-Mdo-062515	Monodelphis domestica	67.07	1.00e-144	506.00
IUUC-Mmu-064341	Mus musculus	83.78	0.00e+00	674.00
IUUC-Mpu-066565	Mustela putorius furo	83.58	6.00e-180	623.00
IUUC-Mlu-066942	Myotis lucifugus	79.28	0.00e+00	634.00
IUUC-Nle-069436	Nomascus leucogenys	86.53	0.00e+00	640.00
IUUC-Opr-070288	Ochotona princeps	79.20	5.00e-165	573.00
IUUC-Ocu-074686	Oryctolagus cuniculus	82.34	0.00e+00	631.00
IUUC-Ola-086894	Oryzias latipes	58.74	7.00e-92	331.00
IUUC-Oga-088585	Otolemur garnettii	77.94	0.00e+00	635.00
IUUC-Oar-089686	Ovis aries	84.39	0.00e+00	660.00
IUUC-Ptr-090461	Pan troglodytes	88.95	3.00e-154	538.00
IUUC-Pan-091887	Papio anubis	83.19	0.00e+00	639.00
IUUC-Psi-093785	Pelodiscus sinensis	69.96	8.00e-113	400.00
IUUC-Pab-098222	Pongo abelii	82.77	0.00e+00	639.00
IUUC-Pca-100668	Procavia capensis	81.80	0.00e+00	634.00
IUUC-Pva-102767	Pteropus vampyrus	71.52	4.00e-152	531.00
IUUC-Rno-106001	Rattus norvegicus	85.12	0.00e+00	671.00
IUUC-Sar-113338	Sorex araneus	75.49	7.00e-161	560.00
IUUC-Ssc-116027	Sus scrofa	81.50	0.00e+00	659.00
IUUC-Tgu-117472	Taeniopygia guttata	57.76	3.00e-148	518.00
IUUC-Tni-119931	Tetraodon nigroviridis	57.60	2.00e-92	333.00
IUUC-Tre-122167	Trichoderma reesei	59.18	9.00e-12	65.50
IUUC-Tvi-122614	Trichoderma virens	59.18	7.00e-12	65.90

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence