iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-097364

Ensembl Protein ID

ENSPFOP00000006945.2

UniProt Accession

A0A087XME2; A0A087XME2_POEFO

Genbank Protein ID

ENSPFOP00000006945

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01019914

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000006898.2	ENSPFOT00000006957.2	ENSPFOP00000006945.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.00e-117	392.9	564	893

Active Site

Position(s)	Description	Evidence
864	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlp 91
           ++lk+ + v+f gEeg+++ Gv re+++ ls+e+ npd+ lf++s+ d +t+qpn++s + np+hl++F+f+G++lg+al++++l+++ 
   Q: 564  EKLKQGIAVRFHGEEGMGQ-GVVREWFDILSNEIINPDYALFTQSA-DGTTFQPNSNSSV-NPDHLNYFQFAGQILGLALYHRQLVNIY 649
           78999**************.**********************6666.67788*******9.89************************** PP
   S: 92   lsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvvey 180
           +++sfyk++lg ++s++d++++dpe++k+l++i++n   di++lgl+ltfsv+++++g ++e+ LkpgG++i Vt++Nk eYv+lv+e+
   Q: 650  FTRSFYKHILGIPVSYQDVSSIDPEYAKNLQWILDN---DISDLGLELTFSVETDVFGAMEEVPLKPGGSSILVTQDNKAEYVQLVTEL 735
           **********************************99...************************************************** PP
   S: 181  rlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvT 269
           r+++ i+ q++af +Gf++ ip++l++lF+e elell++G++eidved+ ++t+y++gy +++p+iqwFw+v++++++eer  +LqFvT
   Q: 736  RMTRAIQPQINAFLQGFHTFIPPSLIQLFDEYELELLLSGMPEIDVEDWCRNTEYTSGYDPEDPVIQWFWKVVRRLTQEERVLLLQFVT 824
           ***************************************************************************************** PP
   S: 270  gssrlPlgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kg 332
           gssr+P+gGfa l+     ++f+i     + + lP+s+TC+n+LkLPeY+++e+l+++Ll+A + +  g
   Q: 825  GSSRVPHGGFAFLMggsgLQKFTIAAvPYTSNLLPTSSTCINMLKLPEYPNQEVLRDRLLVALHCGsYG 893
           ******************88899998677779*******************************986555 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MMERAMEQLN VQLSRLTRSL RRARTVELPE DNETAVYTLM PMVMADQHRS VSELLLNSKF 60
DVNYAFGRVK RSLLHIAANC GSVECLVLLL KRGANPNYQD ISGCTPLHLA ARNGQKKCMG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TACGTCACTC ATACGTCATC ACAACAGGAA GCGTGAGAAT CAGGGGAACA ACGCTGGTTT 60
ACGGGCGGAA GGAACCATTT AAACGCCCAG TAAATCAGCT TGTCTGTTAG AAAAACGGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR000569--HECT_dom

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50237--HECT

Pfam

PF12796--Ank_2
PF00632--HECT

PRINTS

PR01415--ANKYRIN

SMART

SM00248--ANK
SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001490	Ailuropoda melanoleuca	85.90	0.00e+00	1627.00
IUUC-Apl-003400	Anas platyrhynchos	78.94	0.00e+00	1038.00
IUUC-Aca-005375	Anolis carolinensis	85.43	0.00e+00	1630.00
IUUC-Ame-011847	Astyanax mexicanus	90.02	0.00e+00	1729.00
IUUC-Bta-012831	Bos taurus	86.18	0.00e+00	1596.00
IUUC-Cja-019160	Callithrix jacchus	86.20	0.00e+00	1636.00
IUUC-Cfa-020346	Canis familiaris	86.07	0.00e+00	1634.00
IUUC-Cpo-021766	Cavia porcellus	85.75	0.00e+00	1631.00
IUUC-Csa-023768	Chlorocebus sabaeus	86.18	0.00e+00	1639.00
IUUC-Cho-024688	Choloepus hoffmanni	79.11	0.00e+00	988.00
IUUC-Cin-025417	Ciona intestinalis	45.88	2.00e-138	486.00
IUUC-Csv-025993	Ciona savignyi	45.17	0.00e+00	774.00
IUUC-Dre-027819	Danio rerio	90.40	0.00e+00	1707.00
IUUC-Dno-029027	Dasypus novemcinctus	85.41	0.00e+00	1619.00
IUUC-Dor-030327	Dipodomys ordii	79.08	0.00e+00	1427.00
IUUC-Ete-032966	Echinops telfairi	79.89	0.00e+00	1499.00
IUUC-Eca-034339	Equus caballus	86.18	0.00e+00	1634.00
IUUC-Eeu-034544	Erinaceus europaeus	58.46	6.00e-156	545.00
IUUC-Fca-035617	Felis catus	83.64	0.00e+00	1123.00
IUUC-Fal-036687	Ficedula albicollis	82.98	0.00e+00	1623.00
IUUC-Gmo-039508	Gadus morhua	91.57	0.00e+00	865.00
IUUC-Gga-040845	Gallus gallus	83.40	0.00e+00	1637.00
IUUC-Gac-041894	Gasterosteus aculeatus	93.37	0.00e+00	1704.00
IUUC-Ggo-044465	Gorilla gorilla	82.65	0.00e+00	1560.00
IUUC-Hsa-045731	Homo sapiens	86.18	0.00e+00	1639.00
IUUC-Itr-048716	Ictidomys tridecemlineatus	86.68	0.00e+00	1640.00
IUUC-Lch-050436	Latimeria chalumnae	87.53	0.00e+00	1675.00
IUUC-Loc-052287	Lepisosteus oculatus	87.17	0.00e+00	1713.00
IUUC-Laf-053846	Loxodonta africana	86.20	0.00e+00	1640.00
IUUC-Mcc-055845	Macaca mulatta	86.18	0.00e+00	1640.00
IUUC-Meu-056060	Macropus eugenii	90.29	0.00e+00	649.00
IUUC-Mga-059935	Meleagris gallopavo	85.62	0.00e+00	1626.00
IUUC-Mmr-060960	Microcebus murinus	86.18	0.00e+00	1642.00
IUUC-Mdo-061851	Monodelphis domestica	83.40	0.00e+00	1626.00
IUUC-Mmu-063657	Mus musculus	85.42	0.00e+00	1633.00
IUUC-Mpu-066161	Mustela putorius furo	90.95	0.00e+00	766.00
IUUC-Mlu-067354	Myotis lucifugus	84.44	0.00e+00	1555.00
IUUC-Nle-069112	Nomascus leucogenys	86.51	0.00e+00	1640.00
IUUC-Opr-070686	Ochotona princeps	81.32	0.00e+00	746.00
IUUC-Ont-072398	Oreochromis niloticus	92.47	0.00e+00	1703.00
IUUC-Oan-073194	Ornithorhynchus anatinus	86.27	0.00e+00	1580.00
IUUC-Ocu-074397	Oryctolagus cuniculus	78.63	0.00e+00	1446.00
IUUC-Ola-086777	Oryzias latipes	86.51	0.00e+00	1654.00
IUUC-Oga-088684	Otolemur garnettii	86.20	0.00e+00	1636.00
IUUC-Oar-089428	Ovis aries	85.76	0.00e+00	1601.00
IUUC-Ptr-090529	Pan troglodytes	86.07	0.00e+00	1637.00
IUUC-Pan-091702	Papio anubis	86.29	0.00e+00	1641.00
IUUC-Psi-093969	Pelodiscus sinensis	82.93	0.00e+00	1563.00
IUUC-Pab-098574	Pongo abelii	86.18	0.00e+00	1639.00
IUUC-Pca-100525	Procavia capensis	79.83	8.00e-166	577.00
IUUC-Pva-102365	Pteropus vampyrus	75.41	0.00e+00	1377.00
IUUC-Rno-105153	Rattus norvegicus	85.20	0.00e+00	1632.00
IUUC-Sha-107319	Sarcophilus harrisii	83.70	0.00e+00	1627.00
IUUC-Stu-112894	Solanum tuberosum	35.04	2.00e-55	210.00
IUUC-Sar-113449	Sorex araneus	65.58	4.00e-134	472.00
IUUC-Ssc-115865	Sus scrofa	86.07	0.00e+00	1632.00
IUUC-Tgu-117225	Taeniopygia guttata	83.19	0.00e+00	1629.00
IUUC-Tru-118026	Takifugu rubripes	89.42	0.00e+00	1674.00
IUUC-Tsy-119407	Tarsius syrichta	74.10	0.00e+00	1345.00
IUUC-Tni-120234	Tetraodon nigroviridis	91.98	0.00e+00	1352.00
IUUC-Tbe-127708	Tupaia belangeri	73.93	0.00e+00	717.00
IUUC-Ttr-128667	Tursiops truncatus	85.85	0.00e+00	1632.00
IUUC-Vpa-130200	Vicugna pacos	85.94	0.00e+00	1576.00
IUUC-Xtr-132176	Xenopus tropicalis	83.23	0.00e+00	1628.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence