iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004167

Ensembl Protein ID

ENSAPLP00000015484.1

UniProt Accession

U3J7K7; U3J7K7_ANAPL

Genbank Protein ID

ENSAPLP00000015484

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01080149

Gene Name

MID2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000015609.1	ENSAPLT00000016282.1	ENSAPLP00000015484.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.10e-07	30.2	10	60

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw......pglknssskefrCPlCr 46
           C+iCle f+d pl+lpC H  +++C +++         + +  ++f+CP+Cr
   Q: 10   CPICLELFED-PLLLPCAHSLCFSCAHRIlvsscsSSESIEPITAFQCPTCR 60
           **********.999**************9887777666666778889****8 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

METLESELTC PICLELFEDP LLLPCAHSLC FSCAHRILVS SCSSSESIEP ITAFQCPTCR 60
YVISLNHRGL EGLKRNVTLQ NIIDRFQKAS LSGPNSPSES RRERTYRNSP TMSVAGERIA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAAACAC TGGAGTCCGA ATTGACCTGC CCAATCTGCC TGGAGTTATT CGAAGACCCT 60
CTCCTGCTGC CCTGCGCCCA CAGCCTCTGC TTCAGCTGCG CCCACCGCAT CCTGGTGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003649--Bbox_C
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR003961--FN3_dom
IPR013783--Ig-like_fold
IPR033491--MID2
IPR006574--PRY
IPR003877--SPRY_dom
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00502--BBC
SM00336--BBOX
SM00060--FN3
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005874--C:microtubule
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0010508--P:positive regulation of autophagy
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0035372--P:protein localization to microtubule

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001342	Ailuropoda melanoleuca	89.36	0.00e+00	1328.00
IUUC-Cja-019379	Callithrix jacchus	89.09	0.00e+00	1325.00
IUUC-Cfa-021219	Canis familiaris	87.29	0.00e+00	1296.00
IUUC-Cpo-021954	Cavia porcellus	86.60	0.00e+00	1297.00
IUUC-Csa-023047	Chlorocebus sabaeus	87.57	0.00e+00	1303.00
IUUC-Cho-025087	Choloepus hoffmanni	77.46	0.00e+00	685.00
IUUC-Dre-028003	Danio rerio	76.42	0.00e+00	1144.00
IUUC-Dno-029344	Dasypus novemcinctus	87.57	0.00e+00	1300.00
IUUC-Dor-030160	Dipodomys ordii	81.19	0.00e+00	922.00
IUUC-Ete-032883	Echinops telfairi	82.62	0.00e+00	1210.00
IUUC-Eca-033688	Equus caballus	87.57	0.00e+00	1304.00
IUUC-Eeu-034882	Erinaceus europaeus	80.11	0.00e+00	1165.00
IUUC-Fca-036427	Felis catus	89.36	0.00e+00	1328.00
IUUC-Fal-036967	Ficedula albicollis	77.55	0.00e+00	1061.00
IUUC-Gmo-038518	Gadus morhua	71.75	0.00e+00	833.00
IUUC-Gga-040408	Gallus gallus	92.01	0.00e+00	1357.00
IUUC-Gac-041617	Gasterosteus aculeatus	78.26	0.00e+00	1157.00
IUUC-Ggo-045217	Gorilla gorilla	89.23	0.00e+00	1325.00
IUUC-Hsa-045969	Homo sapiens	89.36	0.00e+00	1326.00
IUUC-Itr-049079	Ictidomys tridecemlineatus	89.50	0.00e+00	1329.00
IUUC-Lch-050468	Latimeria chalumnae	82.34	0.00e+00	1180.00
IUUC-Laf-054029	Loxodonta africana	89.64	0.00e+00	1325.00
IUUC-Mcc-055424	Macaca mulatta	89.36	0.00e+00	1328.00
IUUC-Meu-056432	Macropus eugenii	87.76	0.00e+00	1190.00
IUUC-Mga-059599	Meleagris gallopavo	80.30	0.00e+00	1107.00
IUUC-Mmr-061432	Microcebus murinus	88.40	0.00e+00	1316.00
IUUC-Mdo-061989	Monodelphis domestica	87.29	0.00e+00	1286.00
IUUC-Mmu-063963	Mus musculus	89.23	0.00e+00	1324.00
IUUC-Mpu-065964	Mustela putorius furo	87.57	0.00e+00	1303.00
IUUC-Mlu-067148	Myotis lucifugus	87.98	0.00e+00	1305.00
IUUC-Nle-069552	Nomascus leucogenys	87.43	0.00e+00	1301.00
IUUC-Opr-070968	Ochotona princeps	93.36	5.00e-150	524.00
IUUC-Ont-072260	Oreochromis niloticus	75.67	0.00e+00	991.00
IUUC-Ocu-074109	Oryctolagus cuniculus	87.43	0.00e+00	1302.00
IUUC-Oga-089063	Otolemur garnettii	89.23	0.00e+00	1325.00
IUUC-Oar-089845	Ovis aries	87.43	0.00e+00	1303.00
IUUC-Ptr-091360	Pan troglodytes	89.36	0.00e+00	1326.00
IUUC-Pan-092900	Papio anubis	88.58	0.00e+00	1318.00
IUUC-Pfo-096044	Poecilia formosa	75.98	0.00e+00	990.00
IUUC-Pab-098637	Pongo abelii	87.57	0.00e+00	1303.00
IUUC-Pca-100154	Procavia capensis	90.60	0.00e+00	692.00
IUUC-Pva-102319	Pteropus vampyrus	88.67	0.00e+00	1305.00
IUUC-Rno-105496	Rattus norvegicus	87.43	0.00e+00	1299.00
IUUC-Sha-107246	Sarcophilus harrisii	87.02	0.00e+00	1286.00
IUUC-Ssc-115858	Sus scrofa	87.85	0.00e+00	1309.00
IUUC-Tru-118237	Takifugu rubripes	78.78	0.00e+00	1174.00
IUUC-Tsy-119383	Tarsius syrichta	89.43	0.00e+00	1278.00
IUUC-Tni-119919	Tetraodon nigroviridis	79.59	0.00e+00	1184.00
IUUC-Ttr-128902	Tursiops truncatus	89.36	0.00e+00	1328.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence