iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-005319

Ensembl Protein ID

ENSACAP00000006703.1

UniProt Accession

H9GBZ7; H9GBZ7_ANOCA

Protein Name

Uncharacterized protein

Gene Name

LATS1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000006840.2	ENSACAT00000006849.2	ENSACAP00000006703.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	9.20e-08	31.9	103	140

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLl 39
           + ++l+ l++ GFd++ ++qaLr++ + ++eaA+e++ 
   Q: 103  NRQMLQDLQAAGFDEDMVVQALRQTnSRSIEAAIEFIS 140
           669*********************99*********975 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MKRSEKPEGY RQMRPKTFPA SNYTGSSRQM LEEIRKSLKY LPKPSDAAKV EQNVGKIATE 60
DPRQGRNPPK FVTYHKALEE IKNSLEPFAN ETSSSARGIS EVNRQMLQDL QAAGFDEDMV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTGGCTGGC TTAGGATTGA ATGAATGTTT GTACCATTGG AACCACCATC AACAGTGAAT 60
TTCGAAGTTA CCATCCTGTC ATTTTTGAGT GTATTGGTTA GAGGCTACAC GGTTTCATGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR028741--LATS1/Warts
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase
PF00627--UBA

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000922--C:spindle pole
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0051220--P:cytoplasmic sequestering of protein
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0035329--P:hippo signaling
GO:0009755--P:hormone-mediated signaling pathway
GO:0030216--P:keratinocyte differentiation
GO:0007067--P:mitotic nuclear division
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0018105--P:peptidyl-serine phosphorylation
GO:0043065--P:positive regulation of apoptotic process
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0030833--P:regulation of actin filament polymerization
GO:0033146--P:regulation of intracellular estrogen receptor signaling pathway
GO:0046620--P:regulation of organ growth
GO:2000058--P:regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0000819--P:sister chromatid segregation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001895	Ailuropoda melanoleuca	81.79	0.00e+00	1708.00
IUUC-Apl-003278	Anas platyrhynchos	82.35	0.00e+00	1769.00
IUUC-Ame-011324	Astyanax mexicanus	83.43	0.00e+00	939.00
IUUC-Bta-013438	Bos taurus	81.60	0.00e+00	1682.00
IUUC-Cel-018517	Caenorhabditis elegans	49.68	3.00e-128	452.00
IUUC-Cja-019072	Callithrix jacchus	82.31	0.00e+00	1769.00
IUUC-Cfa-021267	Canis familiaris	82.04	0.00e+00	1735.00
IUUC-Cpo-021496	Cavia porcellus	78.43	0.00e+00	1434.00
IUUC-Csa-023255	Chlorocebus sabaeus	82.92	0.00e+00	1759.00
IUUC-Cho-024461	Choloepus hoffmanni	93.83	0.00e+00	751.00
IUUC-Cin-025264	Ciona intestinalis	63.03	5.00e-142	496.00
IUUC-Dre-028034	Danio rerio	80.22	0.00e+00	936.00
IUUC-Dno-029888	Dasypus novemcinctus	79.93	0.00e+00	1712.00
IUUC-Dor-030144	Dipodomys ordii	73.57	0.00e+00	1472.00
IUUC-Dme-031656	Drosophila melanogaster	72.56	0.00e+00	655.00
IUUC-Ete-032813	Echinops telfairi	86.29	0.00e+00	1135.00
IUUC-Eca-033781	Equus caballus	81.25	0.00e+00	1686.00
IUUC-Eeu-035007	Erinaceus europaeus	80.28	0.00e+00	1724.00
IUUC-Fca-036142	Felis catus	77.02	0.00e+00	1611.00
IUUC-Fal-036626	Ficedula albicollis	82.18	0.00e+00	1779.00
IUUC-Gmo-038688	Gadus morhua	84.76	0.00e+00	773.00
IUUC-Gga-040553	Gallus gallus	82.95	0.00e+00	1785.00
IUUC-Gac-042031	Gasterosteus aculeatus	63.16	0.00e+00	1294.00
IUUC-Ggo-045242	Gorilla gorilla	82.34	0.00e+00	1747.00
IUUC-Hsa-046081	Homo sapiens	82.22	0.00e+00	1745.00
IUUC-Itr-048668	Ictidomys tridecemlineatus	82.20	0.00e+00	1502.00
IUUC-Lch-049425	Latimeria chalumnae	76.77	0.00e+00	1660.00
IUUC-Loc-052418	Lepisosteus oculatus	66.04	0.00e+00	1368.00
IUUC-Laf-053710	Loxodonta africana	80.47	0.00e+00	1693.00
IUUC-Mcc-055079	Macaca mulatta	82.75	0.00e+00	1755.00
IUUC-Mga-059713	Meleagris gallopavo	82.72	0.00e+00	1786.00
IUUC-Mmr-061728	Microcebus murinus	82.31	0.00e+00	1731.00
IUUC-Mdo-061942	Monodelphis domestica	81.40	0.00e+00	1741.00
IUUC-Mmu-063504	Mus musculus	80.46	0.00e+00	1676.00
IUUC-Mpu-066034	Mustela putorius furo	81.43	0.00e+00	1717.00
IUUC-Mlu-067986	Myotis lucifugus	81.43	0.00e+00	1709.00
IUUC-Nle-069202	Nomascus leucogenys	82.48	0.00e+00	1756.00
IUUC-Opr-070801	Ochotona princeps	86.82	0.00e+00	1174.00
IUUC-Ont-072487	Oreochromis niloticus	60.74	0.00e+00	1219.00
IUUC-Oan-073128	Ornithorhynchus anatinus	81.96	0.00e+00	1495.00
IUUC-Ocu-073998	Oryctolagus cuniculus	83.46	0.00e+00	1279.00
IUUC-Ola-086858	Oryzias latipes	59.05	0.00e+00	1177.00
IUUC-Oga-088874	Otolemur garnettii	80.76	0.00e+00	1677.00
IUUC-Oar-089236	Ovis aries	81.35	0.00e+00	1682.00
IUUC-Ptr-091425	Pan troglodytes	82.39	0.00e+00	1751.00
IUUC-Pan-091851	Papio anubis	82.69	0.00e+00	1753.00
IUUC-Psi-093825	Pelodiscus sinensis	84.96	0.00e+00	1516.00
IUUC-Pfo-096326	Poecilia formosa	59.66	0.00e+00	1182.00
IUUC-Pab-097815	Pongo abelii	82.48	0.00e+00	1754.00
IUUC-Pva-102836	Pteropus vampyrus	80.46	0.00e+00	1613.00
IUUC-Ptt-103762	Puccinia triticina	39.10	9.00e-94	338.00
IUUC-Rno-106053	Rattus norvegicus	80.72	0.00e+00	1717.00
IUUC-Sha-106843	Sarcophilus harrisii	81.79	0.00e+00	1745.00
IUUC-Sar-113649	Sorex araneus	80.56	0.00e+00	1364.00
IUUC-Ssc-115486	Sus scrofa	91.43	0.00e+00	803.00
IUUC-Tgu-116903	Taeniopygia guttata	82.35	0.00e+00	1777.00
IUUC-Tru-118760	Takifugu rubripes	62.92	0.00e+00	1303.00
IUUC-Tsy-119361	Tarsius syrichta	81.65	0.00e+00	1485.00
IUUC-Tni-120058	Tetraodon nigroviridis	58.04	0.00e+00	1160.00
IUUC-Tbe-127681	Tupaia belangeri	82.16	0.00e+00	1374.00
IUUC-Ttr-128652	Tursiops truncatus	81.08	0.00e+00	1439.00
IUUC-Vpa-130538	Vicugna pacos	80.93	0.00e+00	1706.00
IUUC-Xtr-132895	Xenopus tropicalis	72.70	0.00e+00	1274.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence