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Tag Content
UUCD2 ID IUUC-Dre-028577
UUCD1 version UUC-DaR-00294
Ensembl Protein ID ENSDARP00000032728.6
UniProt Accession E7F165; E7F165_DANRE
Genbank Protein ID ENSDARP00000032728
Protein Name Tumor necrosis factor, alpha-induced protein 3
Genbank Nucleotide ID BX323887
Gene Name tnfaip3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000027777.9 ENSDART00000147959.1 ENSDARP00000123481.1
ENSDARG00000027777.9 ENSDART00000033528.7 ENSDARP00000032728.6
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/OTU 2.20e-33 116.5 97 264
UBD/ZnF/ZnF_A20 3.40e-14 53.4 729 761
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/OTU
   S: 2    lilktkgDGnCLlrAvsqsllgvfddds.lsdalveaLreltseyl....qkesdffsefieek........edekefcqklvepeakg 77
           ++l t+gDGnCLl+A+sq+llgv+d+d+ l++al+ +L+e+ +  +    q e  + +ef +++        e+e+  + ++++p + +
   Q: 97   VPLRTNGDGNCLLHAASQYLLGVQDTDLvLRKALHAVLKETDTTDFltrfQTELLHSQEFTQTGlrystlnwEEEWVKIVDMASPVSSS 185
           7899************************************9888777998999999999999999********************9765 PP
   S: 78   ........eeihifaLaqiLsrpiivvdvdsles..........kvggillpllfpeek.lkkpivLlYrsgHYdaLva 137
                   e ihif+L++iL+rpiiv++++ l+s          +vggi+lpl++p+ + +k+pivL+Y+s H+ +L++
   Q: 186  nglqfdslEDIHIFVLSNILRRPIIVIADQVLRSmksgssfsplNVGGIYLPLHWPPGEcYKYPIVLGYDSQHFAPLIT 264
           56*******************************9******************************************986 PP
   

   UBD/ZnF/ZnF_A20
   S: 3    skllCkk.gCgfYGnpetngyCSkCyreelrrr 34
           sk++Ck+ gC++Y n e +gyC++C  +++ +r
   Q: 729  SKQRCKTqGCDHYANQEKQGYCNECDHFKQIYR 761
           89***********************99998776 PP
   
Organism Danio rerio
Protein Sequence
(Fasta)
MSQGQNFLPK FLFVSNLLKA VKIRERVPND VVKPSAGGSL IHHLRSMHRY TLEMIRMSQF 60
PQAFREVIQA AILDRAMQSS LEQEKRLNWC REVKKLVPLR TNGDGNCLLH AASQYLLGVQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dre-028577|DUB,OTU;UBD,ZnF_A20|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTCTGAAAGG AAAGTACCTT ATGGAAATCC CCTACTGGCT TTTATGTACA GCTAACAATC 60
GGGCTGGTTT GACTAGAGAG CGTGTTGTGG AGGCGAGCAG AGAAATCCAG CGGCTCTCCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-028577|DUB,OTU;UBD,ZnF_A20|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR033478--A20
IPR003323--OTU_dom
IPR002653--Znf_A20
PROSITE

PS50802--OTU
PS51036--ZF_A20
Pfam

PF02338--OTU
PF01754--zf-A20
SMART

SM00259--ZnF_A20
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0070530--F:K63-linked polyubiquitin binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0006955--P:immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0071947--P:protein deubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0016567--P:protein ubiquitination
GO:0050727--P:regulation of inflammatory response
GO:0045088--P:regulation of innate immune response
KEGG dre:564497
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001825 Ailuropoda melanoleuca 49.13 0.00e+00 742.00
IUUC-Apl-003501 Anas platyrhynchos 48.57 0.00e+00 721.00
IUUC-Aca-004245 Anolis carolinensis 48.83 0.00e+00 740.00
IUUC-Ame-011789 Astyanax mexicanus 82.79 0.00e+00 1261.00
IUUC-Bta-012664 Bos taurus 49.56 0.00e+00 737.00
IUUC-Cja-019895 Callithrix jacchus 48.58 0.00e+00 731.00
IUUC-Cfa-020754 Canis familiaris 49.50 0.00e+00 746.00
IUUC-Cpo-021780 Cavia porcellus 48.14 0.00e+00 723.00
IUUC-Csa-023568 Chlorocebus sabaeus 48.26 0.00e+00 731.00
IUUC-Cho-024300 Choloepus hoffmanni 61.76 1.00e-125 444.00
IUUC-Dno-029382 Dasypus novemcinctus 50.25 0.00e+00 739.00
IUUC-Dor-030874 Dipodomys ordii 47.22 0.00e+00 701.00
IUUC-Ete-032721 Echinops telfairi 60.14 6.00e-150 525.00
IUUC-Eca-033596 Equus caballus 48.32 0.00e+00 712.00
IUUC-Eeu-035159 Erinaceus europaeus 45.37 2.00e-148 519.00
IUUC-Fca-035847 Felis catus 48.82 0.00e+00 741.00
IUUC-Fal-036681 Ficedula albicollis 47.84 0.00e+00 728.00
IUUC-Gmo-038521 Gadus morhua 88.15 0.00e+00 727.00
IUUC-Gga-040975 Gallus gallus 48.16 0.00e+00 733.00
IUUC-Gac-042216 Gasterosteus aculeatus 73.91 0.00e+00 1070.00
IUUC-Ggo-045258 Gorilla gorilla 47.71 0.00e+00 726.00
IUUC-Hsa-046071 Homo sapiens 48.20 0.00e+00 732.00
IUUC-Itr-048386 Ictidomys tridecemlineatus 48.51 0.00e+00 733.00
IUUC-Lch-050326 Latimeria chalumnae 52.21 0.00e+00 795.00
IUUC-Loc-051945 Lepisosteus oculatus 59.19 0.00e+00 806.00
IUUC-Laf-053722 Loxodonta africana 47.71 0.00e+00 724.00
IUUC-Mcc-055503 Macaca mulatta 48.13 0.00e+00 729.00
IUUC-Meu-056481 Macropus eugenii 45.11 0.00e+00 642.00
IUUC-Mga-059690 Meleagris gallopavo 46.79 0.00e+00 679.00
IUUC-Mmr-061233 Microcebus murinus 48.70 0.00e+00 731.00
IUUC-Mdo-062446 Monodelphis domestica 48.88 0.00e+00 736.00
IUUC-Mmu-063436 Mus musculus 48.50 0.00e+00 732.00
IUUC-Mpu-066808 Mustela putorius furo 49.38 0.00e+00 749.00
IUUC-Mlu-067339 Myotis lucifugus 48.94 0.00e+00 733.00
IUUC-Nle-069888 Nomascus leucogenys 47.96 0.00e+00 728.00
IUUC-Opr-070303 Ochotona princeps 48.95 0.00e+00 737.00
IUUC-Ont-072283 Oreochromis niloticus 86.71 0.00e+00 726.00
IUUC-Oan-072925 Ornithorhynchus anatinus 50.50 0.00e+00 761.00
IUUC-Ocu-073889 Oryctolagus cuniculus 48.44 0.00e+00 730.00
IUUC-Ola-087417 Oryzias latipes 86.92 0.00e+00 723.00
IUUC-Oga-088708 Otolemur garnettii 48.56 0.00e+00 694.00
IUUC-Oar-089271 Ovis aries 48.87 0.00e+00 733.00
IUUC-Ptr-091296 Pan troglodytes 48.20 0.00e+00 732.00
IUUC-Pan-092474 Papio anubis 48.01 0.00e+00 728.00
IUUC-Psi-093447 Pelodiscus sinensis 49.07 0.00e+00 752.00
IUUC-Pfo-096511 Poecilia formosa 71.72 0.00e+00 1077.00
IUUC-Pab-098700 Pongo abelii 48.08 0.00e+00 728.00
IUUC-Pca-100246 Procavia capensis 46.59 7.00e-138 484.00
IUUC-Pva-102606 Pteropus vampyrus 50.90 2.00e-112 400.00
IUUC-Rno-105818 Rattus norvegicus 49.62 0.00e+00 745.00
IUUC-Sha-106559 Sarcophilus harrisii 47.74 0.00e+00 723.00
IUUC-Sar-113454 Sorex araneus 63.83 7.00e-128 451.00
IUUC-Ssc-116064 Sus scrofa 49.37 0.00e+00 736.00
IUUC-Tgu-117212 Taeniopygia guttata 47.49 0.00e+00 717.00
IUUC-Tru-118230 Takifugu rubripes 87.83 0.00e+00 742.00
IUUC-Tsy-119066 Tarsius syrichta 50.06 0.00e+00 748.00
IUUC-Tni-119825 Tetraodon nigroviridis 75.22 0.00e+00 1097.00
IUUC-Tbe-127601 Tupaia belangeri 63.83 8.00e-127 447.00
IUUC-Ttr-128930 Tursiops truncatus 49.38 0.00e+00 731.00
IUUC-Vpa-130450 Vicugna pacos 62.22 6.00e-147 514.00
Created Date 25-Jun-2017

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