iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033674

Ensembl Protein ID

ENSECAP00000017620.1

UniProt Accession

F7BU30; F7BU30_HORSE

Protein Name

Uncharacterized protein

Gene Name

MYLIP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000020010.1	ENSECAT00000021397.1	ENSECAP00000017620.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	95.99	0.00e+00	873.00	IUUC-Hsa-046869

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Equus caballus

Protein Sequence
(Fasta)

MLCYVTRPDA VLMEVEVEAK ANGEDCLNQV CRRLGIIEVD YFGLQFTGSK GESLWLNLRN 60
RISQQMDGLA PYRLKLRVKF FVEPHLILQE QTRHIFFLHI KEALLAGHLQ CSPEQAVELS 120

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Nucleotide Sequence
(Fasta)

ATGCTGTGCT ATGTGACGAG GCCGGACGCG GTGCTGATGG AGGTGGAGGT GGAGGCGAAA 60
GCCAACGGCG AGGACTGCCT CAACCAGGTG AGGACGCGGG GCCAGGCAGG GGGACCCCCA 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR019749--Band_41_domain
IPR001370--BIR_rpt
IPR000798--Ez/rad/moesin-like
IPR014352--FERM/acyl-CoA-bd_prot_3-hlx
IPR019748--FERM_central
IPR000299--FERM_domain
IPR018979--FERM_N
IPR018980--FERM_PH-like_C
IPR011993--PH_dom-like
IPR029071--Ubiquitin-rel_dom
IPR001841--Znf_RING

PROSITE

PS50057--FERM_3
PS50089--ZF_RING_2

Pfam

PF09380--FERM_C
PF00373--FERM_M
PF09379--FERM_N

PRINTS

PR00935--BAND41
PR00661--ERMFAMILY

SMART

SM00295--B41
SM01196--FERM_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019898--C:extrinsic component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0042632--P:cholesterol homeostasis
GO:0010989--P:negative regulation of low-density lipoprotein particle clearance
GO:0007399--P:nervous system development
GO:0045732--P:positive regulation of protein catabolic process
GO:0031648--P:protein destabilization
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0032803--P:regulation of low-density lipoprotein particle receptor catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001425	Ailuropoda melanoleuca	94.29	0.00e+00	826.00
IUUC-Apl-003704	Anas platyrhynchos	89.36	0.00e+00	770.00
IUUC-Aca-004645	Anolis carolinensis	88.20	0.00e+00	793.00
IUUC-Ame-011401	Astyanax mexicanus	73.66	0.00e+00	650.00
IUUC-Bta-012752	Bos taurus	93.75	0.00e+00	705.00
IUUC-Cja-019734	Callithrix jacchus	95.55	0.00e+00	844.00
IUUC-Cfa-020145	Canis familiaris	94.27	0.00e+00	751.00
IUUC-Cpo-021436	Cavia porcellus	94.01	0.00e+00	724.00
IUUC-Csa-024248	Chlorocebus sabaeus	95.55	0.00e+00	845.00
IUUC-Cho-024528	Choloepus hoffmanni	82.85	0.00e+00	685.00
IUUC-Cin-025748	Ciona intestinalis	36.33	1.00e-47	182.00
IUUC-Csv-025837	Ciona savignyi	38.11	7.00e-90	324.00
IUUC-Dre-027847	Danio rerio	74.67	0.00e+00	667.00
IUUC-Dno-029860	Dasypus novemcinctus	93.75	0.00e+00	699.00
IUUC-Dor-030664	Dipodomys ordii	97.27	1.00e-128	452.00
IUUC-Dse-031509	Dothistroma septosporum	43.14	4.00e-09	57.00
IUUC-Dme-031990	Drosophila melanogaster	30.86	1.00e-36	147.00
IUUC-Ete-032496	Echinops telfairi	74.73	7.00e-154	536.00
IUUC-Eeu-035048	Erinaceus europaeus	87.08	0.00e+00	793.00
IUUC-Fca-036547	Felis catus	94.05	0.00e+00	821.00
IUUC-Fal-037504	Ficedula albicollis	89.55	0.00e+00	757.00
IUUC-Gmo-038660	Gadus morhua	73.26	8.00e-151	526.00
IUUC-Gga-040123	Gallus gallus	89.98	0.00e+00	806.00
IUUC-Gac-042073	Gasterosteus aculeatus	71.02	1.00e-180	625.00
IUUC-Ggo-045387	Gorilla gorilla	95.99	0.00e+00	848.00
IUUC-Hsa-046869	Homo sapiens	95.99	0.00e+00	852.00
IUUC-Itr-047917	Ictidomys tridecemlineatus	93.10	0.00e+00	831.00
IUUC-Lch-049990	Latimeria chalumnae	82.41	0.00e+00	781.00
IUUC-Lpe-051271	Leersia perrieri	39.62	3.00e-07	53.50
IUUC-Loc-051908	Lepisosteus oculatus	75.44	0.00e+00	681.00
IUUC-Lma-053223	Leptosphaeria maculans	41.79	4.00e-08	54.30
IUUC-Laf-053915	Loxodonta africana	93.76	0.00e+00	831.00
IUUC-Mcc-054865	Macaca mulatta	95.32	0.00e+00	843.00
IUUC-Meu-056826	Macropus eugenii	87.66	7.00e-76	277.00
IUUC-Mga-059827	Meleagris gallopavo	89.05	0.00e+00	726.00
IUUC-Mmr-060734	Microcebus murinus	95.32	0.00e+00	862.00
IUUC-Mdo-062988	Monodelphis domestica	93.32	0.00e+00	874.00
IUUC-Mmu-064415	Mus musculus	93.99	0.00e+00	803.00
IUUC-Mpu-066118	Mustela putorius furo	94.53	0.00e+00	717.00
IUUC-Mlu-067131	Myotis lucifugus	94.43	0.00e+00	853.00
IUUC-Nle-070112	Nomascus leucogenys	95.77	0.00e+00	845.00
IUUC-Opr-071193	Ochotona princeps	91.20	0.00e+00	785.00
IUUC-Ont-072635	Oreochromis niloticus	71.94	0.00e+00	640.00
IUUC-Oan-073266	Ornithorhynchus anatinus	89.29	0.00e+00	761.00
IUUC-Ocu-074903	Oryctolagus cuniculus	91.76	0.00e+00	828.00
IUUC-Oba-075143	Oryza barthii	39.62	3.00e-07	53.50
IUUC-Ome-081491	Oryza meridionalis	39.62	3.00e-07	53.50
IUUC-Osa-085816	Oryza sativa	39.62	5.00e-08	51.60
IUUC-Ola-087533	Oryzias latipes	69.55	2.00e-175	608.00
IUUC-Oga-087979	Otolemur garnettii	95.32	0.00e+00	870.00
IUUC-Oar-089747	Ovis aries	93.81	0.00e+00	777.00
IUUC-Ptr-090732	Pan troglodytes	96.21	0.00e+00	850.00
IUUC-Pan-092032	Papio anubis	95.55	0.00e+00	845.00
IUUC-Psi-093296	Pelodiscus sinensis	89.36	0.00e+00	793.00
IUUC-Pma-094351	Petromyzon marinus	51.14	3.00e-33	134.00
IUUC-Pfo-097183	Poecilia formosa	72.17	3.00e-173	601.00
IUUC-Pab-098177	Pongo abelii	95.77	0.00e+00	847.00
IUUC-Pca-100734	Procavia capensis	92.20	0.00e+00	831.00
IUUC-Pva-102778	Pteropus vampyrus	96.43	0.00e+00	840.00
IUUC-Rno-106039	Rattus norvegicus	93.76	0.00e+00	829.00
IUUC-Sha-106869	Sarcophilus harrisii	93.33	0.00e+00	815.00
IUUC-Sar-113587	Sorex araneus	88.48	8.00e-87	313.00
IUUC-Ssc-116212	Sus scrofa	94.65	0.00e+00	834.00
IUUC-Tgu-116871	Taeniopygia guttata	89.31	0.00e+00	755.00
IUUC-Tru-117925	Takifugu rubripes	72.79	0.00e+00	673.00
IUUC-Tsy-118815	Tarsius syrichta	93.57	0.00e+00	784.00
IUUC-Tni-120007	Tetraodon nigroviridis	72.99	0.00e+00	641.00
IUUC-Tbe-127381	Tupaia belangeri	91.29	0.00e+00	675.00
IUUC-Ttr-129025	Tursiops truncatus	80.24	0.00e+00	645.00
IUUC-Vpa-130164	Vicugna pacos	70.82	1.00e-155	542.00
IUUC-Xtr-132800	Xenopus tropicalis	81.74	0.00e+00	745.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence