iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-072703

UUCD1 version

UUC-OrA-00374

Ensembl Protein ID

ENSOANP00000018539.2

UniProt Accession

F7A1C6; F7A1C6_ORNAN

Protein Name

Uncharacterized protein

Gene Name

ATG16L1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000011698.3	ENSOANT00000018542.2	ENSOANP00000018539.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.60e-29	99.8	422	460
UBD/Beta-Prp	5.20e-58	196.8	333	621

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH+++v + +f  +  l+vsGs+D t+k+W+l +  ++k
   Q: 422  GHSGKVLSAKFlLGkSLIVSGSHDRTLKLWNLQSRICTK 460
           8***********44479**************99888876 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk 91
           ++++h++ +++v+f p+++llatg++d+++k+w+v+   +    s+ g +a++t+++f++ g++l+ +s+D + ++w ++++   htl+
   Q: 333  YFNAHDGEVNAVQFDPSSRLLATGGMDRRVKLWEVFGDRCelKGSFAGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYWLRHTLT 421
           6789********************************9999878999******************************************* PP
   S: 92   ghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgght 180
           gh+ +vls +f   ++ +vsGshdrt+++w+l+++ c +++++g +    c  + +++++++sG+ D+++r+Wd++ ++++r+++    
   Q: 422  GHSGKVLSAKFLLGKSLIVSGSHDRTLKLWNLQSRICTKTVFAGSS----CNDIVCTEQCVMSGHFDKKIRFWDIRAESIIREME--LL 504
           *************99************************9999988....888888889*************************6..69 PP
   S: 181  dsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght....dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhns 265
           ++++ l+++++++el+s+s+d+ +++ dl+ + + +t+ +      +  ++v fsp++ +++ gs++gs+++W++ +g++ k+l++ +s
   Q: 505  GKITALDLNPERTELLSCSRDNLLNIIDLRVNAIKQTFSAPGfkcgSDWTRVVFSPDGSYVAAGSAEGSLYVWNVLTGKVEKVLSKFHS 593
           ******************************99998888887777776677799************************************ PP
   S: 266  svisvavlsfgdnvlvlgsedskvniwk 293
           s+i   ++s+++ ++v++++ +k+ +w+
   Q: 594  SSINAVAWSPSGVHVVSVDKSNKAVVWS 621
           ********************99****96 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MAAGLRAPGL PGWRRHISEE LRRRDRLQRQ AFEEIILQYN KLLEKSDLQS VLAGKLQAEK 60
YDMQSKHEIS QGHDGMWNNS QLQEMAQMRI KHQEELTELH KKRGELAQSV IDLNNQMQQK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGAGCAGTG AGGCGAGCTC TCCTGGCCAC TGCCAAAATG GCCGCCTGCT CTTGTCAAGG 60
GCGCTAACAG AGCCACCCCG AAAATGGCCG CCGGCGGGCC GGGAGGGTCA CGTGTCTCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000421--C:autophagosome membrane
GO:0005930--C:axoneme
GO:0000045--P:autophagosome assembly
GO:0039689--P:negative stranded viral RNA replication

KEGG

oaa:100092288

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000090	Aegilops tauschii	28.20	5.00e-33	135.00
IUUC-Aml-002242	Ailuropoda melanoleuca	78.61	0.00e+00	916.00
IUUC-Atr-003073	Amborella trichopoda	29.53	2.00e-28	119.00
IUUC-Apl-003384	Anas platyrhynchos	81.28	0.00e+00	996.00
IUUC-Aca-004962	Anolis carolinensis	82.83	0.00e+00	1020.00
IUUC-Aly-005435	Arabidopsis lyrata	34.10	6.00e-46	177.00
IUUC-Ath-006948	Arabidopsis thaliana	34.75	2.00e-46	179.00
IUUC-Ame-010915	Astyanax mexicanus	74.54	3.00e-144	503.00
IUUC-Bta-012388	Bos taurus	85.23	0.00e+00	1053.00
IUUC-Bdi-014231	Brachypodium distachyon	30.23	9.00e-38	150.00
IUUC-Bol-016174	Brassica oleracea	35.08	2.00e-46	179.00
IUUC-Bra-017165	Brassica rapa	34.75	1.00e-46	180.00
IUUC-Cel-018131	Caenorhabditis elegans	37.67	2.00e-56	213.00
IUUC-Cja-018898	Callithrix jacchus	73.29	0.00e+00	847.00
IUUC-Cfa-020484	Canis familiaris	82.99	0.00e+00	1016.00
IUUC-Cpo-022156	Cavia porcellus	80.97	0.00e+00	979.00
IUUC-Csa-024019	Chlorocebus sabaeus	80.26	0.00e+00	966.00
IUUC-Cho-024311	Choloepus hoffmanni	71.15	0.00e+00	853.00
IUUC-Cin-025260	Ciona intestinalis	35.09	2.00e-94	339.00
IUUC-Csv-025836	Ciona savignyi	42.03	2.00e-45	174.00
IUUC-Dre-027702	Danio rerio	71.27	0.00e+00	862.00
IUUC-Dno-029728	Dasypus novemcinctus	84.46	0.00e+00	1061.00
IUUC-Dor-030587	Dipodomys ordii	72.85	2.00e-103	369.00
IUUC-Dme-031595	Drosophila melanogaster	38.08	9.00e-104	370.00
IUUC-Ete-032969	Echinops telfairi	67.57	0.00e+00	702.00
IUUC-Eca-034214	Equus caballus	83.66	0.00e+00	848.00
IUUC-Eeu-034537	Erinaceus europaeus	78.66	0.00e+00	815.00
IUUC-Fca-036005	Felis catus	84.94	0.00e+00	981.00
IUUC-Fal-037593	Ficedula albicollis	83.10	0.00e+00	979.00
IUUC-Gmo-039042	Gadus morhua	61.76	0.00e+00	661.00
IUUC-Gga-040986	Gallus gallus	83.47	0.00e+00	1036.00
IUUC-Gac-041351	Gasterosteus aculeatus	70.59	0.00e+00	872.00
IUUC-Gma-043452	Glycine max	33.33	3.00e-47	182.00
IUUC-Ggo-045427	Gorilla gorilla	83.65	0.00e+00	1011.00
IUUC-Hsa-046632	Homo sapiens	82.18	0.00e+00	1002.00
IUUC-Itr-048504	Ictidomys tridecemlineatus	79.45	0.00e+00	955.00
IUUC-Lch-049439	Latimeria chalumnae	48.88	5.00e-144	504.00
IUUC-Lpe-051254	Leersia perrieri	28.81	1.00e-37	150.00
IUUC-Loc-052610	Lepisosteus oculatus	72.79	0.00e+00	890.00
IUUC-Laf-053936	Loxodonta africana	83.49	0.00e+00	1011.00
IUUC-Mcc-055504	Macaca mulatta	81.05	0.00e+00	1026.00
IUUC-Meu-056516	Macropus eugenii	81.25	0.00e+00	971.00
IUUC-Mtr-058062	Medicago truncatula	32.01	9.00e-45	174.00
IUUC-Mga-059777	Meleagris gallopavo	79.22	0.00e+00	988.00
IUUC-Mmr-061298	Microcebus murinus	85.39	0.00e+00	1026.00
IUUC-Mdo-062969	Monodelphis domestica	87.02	0.00e+00	1068.00
IUUC-Mmu-064076	Mus musculus	84.22	0.00e+00	1013.00
IUUC-Mac-065022	Musa acuminata	32.01	1.00e-40	159.00
IUUC-Mpu-066196	Mustela putorius furo	85.39	0.00e+00	1025.00
IUUC-Mlu-067651	Myotis lucifugus	81.57	0.00e+00	996.00
IUUC-Nle-069853	Nomascus leucogenys	80.74	0.00e+00	982.00
IUUC-Opr-070350	Ochotona princeps	86.27	4.00e-109	388.00
IUUC-Ont-072489	Oreochromis niloticus	71.19	0.00e+00	864.00
IUUC-Ocu-074205	Oryctolagus cuniculus	82.48	0.00e+00	1018.00
IUUC-Oba-075619	Oryza barthii	29.82	6.00e-36	144.00
IUUC-Obr-076632	Oryza brachyantha	28.99	2.00e-37	149.00
IUUC-Ogl-077671	Oryza glaberrima	29.82	6.00e-36	144.00
IUUC-Ogu-078052	Oryza glumaepatula	29.82	7.00e-36	144.00
IUUC-Oin-079611	Oryza indica	29.47	1.00e-33	137.00
IUUC-Olo-080408	Oryza longistaminata	29.82	1.00e-35	143.00
IUUC-Ome-081560	Oryza meridionalis	29.82	5.00e-36	144.00
IUUC-Oni-082145	Oryza nivara	29.82	6.00e-36	144.00
IUUC-Opu-083918	Oryza punctata	29.47	3.00e-35	142.00
IUUC-Oru-084858	Oryza rufipogon	29.47	1.00e-33	137.00
IUUC-Osa-086277	Oryza sativa	29.47	1.00e-33	137.00
IUUC-Ola-086816	Oryzias latipes	68.38	1.00e-97	348.00
IUUC-Olu-087622	Ostreococcus lucimarinus	32.89	3.00e-42	165.00
IUUC-Oga-088765	Otolemur garnettii	79.49	0.00e+00	929.00
IUUC-Oar-090196	Ovis aries	82.48	0.00e+00	924.00
IUUC-Ptr-091676	Pan troglodytes	82.34	0.00e+00	1004.00
IUUC-Pan-092068	Papio anubis	84.29	0.00e+00	1016.00
IUUC-Psi-093367	Pelodiscus sinensis	82.18	0.00e+00	1000.00
IUUC-Ppa-095699	Physcomitrella patens	28.13	2.00e-41	162.00
IUUC-Pfo-096067	Poecilia formosa	69.72	0.00e+00	841.00
IUUC-Pab-098111	Pongo abelii	83.81	0.00e+00	1014.00
IUUC-Pop-099116	Populus trichocarpa	31.02	4.00e-43	168.00
IUUC-Pca-100680	Procavia capensis	75.21	0.00e+00	836.00
IUUC-Ppe-101790	Prunus persica	31.46	1.00e-44	173.00
IUUC-Pva-102871	Pteropus vampyrus	82.59	0.00e+00	952.00
IUUC-Rno-106088	Rattus norvegicus	83.41	0.00e+00	1002.00
IUUC-Sha-106984	Sarcophilus harrisii	84.15	0.00e+00	1021.00
IUUC-Smo-109404	Selaginella moellendorffii	31.44	2.00e-40	159.00
IUUC-Sit-110828	Setaria italica	30.87	1.00e-41	163.00
IUUC-Sly-111009	Solanum lycopersicum	31.80	1.00e-44	173.00
IUUC-Stu-112370	Solanum tuberosum	32.46	1.00e-46	180.00
IUUC-Sar-113659	Sorex araneus	54.17	8.00e-75	273.00
IUUC-Sbi-114819	Sorghum bicolor	30.62	1.00e-39	157.00
IUUC-Ssc-116241	Sus scrofa	80.72	0.00e+00	981.00
IUUC-Tgu-116576	Taeniopygia guttata	81.06	0.00e+00	1022.00
IUUC-Tru-118336	Takifugu rubripes	63.67	0.00e+00	719.00
IUUC-Tsy-119006	Tarsius syrichta	80.74	0.00e+00	960.00
IUUC-Tni-120300	Tetraodon nigroviridis	70.59	0.00e+00	838.00
IUUC-Tca-121002	Theobroma cacao	31.68	7.00e-46	177.00
IUUC-Tae-124868	Triticum aestivum	28.85	5.00e-34	138.00
IUUC-Tur-126463	Triticum urartu	28.20	2.00e-33	137.00
IUUC-Tbe-127631	Tupaia belangeri	82.96	0.00e+00	816.00
IUUC-Ttr-129005	Tursiops truncatus	75.23	1.00e-145	509.00
IUUC-Vpa-130246	Vicugna pacos	75.83	0.00e+00	751.00
IUUC-Vvi-130878	Vitis vinifera	33.02	1.00e-43	170.00
IUUC-Xtr-132798	Xenopus tropicalis	70.54	0.00e+00	852.00
IUUC-Xma-133264	Xiphophorus maculatus	69.56	0.00e+00	840.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence