iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-027708

Ensembl Protein ID

ENSDARP00000055170.5

UniProt Accession

F1R1D5; F1R1D5_DANRE

Genbank Protein ID

ENSDARP00000055170

Protein Name

GRB2-related adaptor protein a

Genbank Nucleotide ID

BX322795

Gene Name

grapa

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000005414.8	ENSDART00000055171.5	ENSDARP00000055170.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.80e-23	82.1	4	54

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            +ly++ a+++deL+++kGdv+++  + e d +W  +  e  +++G +P+n++ 
   Q: 4    VALYNFCATESDELSFQKGDVLKIT-NMEDDPNWYTA--EFVNRKGYVPKNYIS 54
           68**********************8.9********99..9************95 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MEAVALYNFC ATESDELSFQ KGDVLKITNM EDDPNWYTAE FVNRKGYVPK NYISLRPHAW 60
FAGRISRHVA ENRLHQRDCG SFLVRESESA PGEFSMSVSY GDHVQHFKVL KDREGYYFVW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTATCAGGGT GAAGTGTTTG ACAGCGAGCG TGTCTCTGGA CGCTCCGGTT CAGTGTGGAT 60
GCTCTCTGGA CTCCTCTTTT CCTCTGTTCA GGATTCTGTG GTGGGACGAT TACATACATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-010699	Astyanax mexicanus	81.78	2.00e-106	378.00
IUUC-Fal-037633	Ficedula albicollis	63.26	5.00e-78	283.00
IUUC-Gmo-039547	Gadus morhua	52.17	4.00e-71	261.00
IUUC-Gac-041947	Gasterosteus aculeatus	77.10	2.00e-96	344.00
IUUC-Loc-052457	Lepisosteus oculatus	79.91	2.00e-103	368.00
IUUC-Ont-071576	Oreochromis niloticus	77.31	2.00e-97	348.00
IUUC-Ola-086725	Oryzias latipes	74.77	2.00e-96	345.00
IUUC-Pfo-096278	Poecilia formosa	79.81	2.00e-101	361.00
IUUC-Tru-118065	Takifugu rubripes	79.44	6.00e-102	363.00
IUUC-Tni-120563	Tetraodon nigroviridis	75.81	7.00e-94	336.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence