iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074192

UUCD1 version

UUC-OrC-00119

Ensembl Protein ID

ENSOCUP00000002677.2

UniProt Accession

G1SIZ7; G1SIZ7_RABIT

Protein Name

Uncharacterized protein

Gene Name

TRIM13

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000003083.2	ENSOCUT00000003080.2	ENSOCUP00000002677.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.40e-08	34.4	12	60

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw....pglknssskefrCPlCr 46
           C+iC++ f+d p+vlpC H f+++Cl+ +    +  +      f+CP+Cr
   Q: 12   CPICCSLFDD-PRVLPCSHNFCKKCLEGLlegnVRNSLWRPSPFKCPTCR 60
           ********99.**************96666666666666999999****8 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

DVMELLEEDL TCPICCSLFD DPRVLPCSHN FCKKCLEGLL EGNVRNSLWR PSPFKCPTCR 60
KETSATGVNS LQVNYSLKGI VEKYNKIKIS PKMPVCKGHL GQPLNIFCLT DMQLICGICA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATGTGATGG AGCTGCTTGA AGAAGATCTG ACGTGCCCAA TCTGTTGCAG TCTGTTTGAT 60
GATCCACGAG TGTTGCCTTG CTCACACAAC TTCTGCAAAA AATGCTTGGA AGGTCTCTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0097038--C:perinuclear endoplasmic reticulum
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0010942--P:positive regulation of cell death
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016239--P:positive regulation of macroautophagy
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0051865--P:protein autoubiquitination
GO:0010332--P:response to gamma radiation
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002269	Ailuropoda melanoleuca	93.40	0.00e+00	739.00
IUUC-Apl-004168	Anas platyrhynchos	76.72	0.00e+00	637.00
IUUC-Aca-004395	Anolis carolinensis	70.59	5.00e-167	580.00
IUUC-Ame-011325	Astyanax mexicanus	46.13	5.00e-67	248.00
IUUC-Bta-012613	Bos taurus	92.87	0.00e+00	733.00
IUUC-Cja-018856	Callithrix jacchus	92.18	0.00e+00	773.00
IUUC-Cfa-021019	Canis familiaris	94.62	0.00e+00	739.00
IUUC-Cpo-021845	Cavia porcellus	92.38	0.00e+00	726.00
IUUC-Csa-023380	Chlorocebus sabaeus	91.65	0.00e+00	732.00
IUUC-Cho-024733	Choloepus hoffmanni	84.62	4.00e-90	325.00
IUUC-Dre-028675	Danio rerio	49.28	3.00e-112	398.00
IUUC-Dno-030018	Dasypus novemcinctus	91.67	0.00e+00	726.00
IUUC-Dor-030599	Dipodomys ordii	89.51	7.00e-126	442.00
IUUC-Dse-031522	Dothistroma septosporum	32.89	7.00e-06	44.70
IUUC-Ete-033134	Echinops telfairi	89.02	0.00e+00	731.00
IUUC-Eca-033931	Equus caballus	94.13	0.00e+00	737.00
IUUC-Eeu-034903	Erinaceus europaeus	91.93	0.00e+00	726.00
IUUC-Fca-035642	Felis catus	92.63	0.00e+00	721.00
IUUC-Fal-037108	Ficedula albicollis	76.72	0.00e+00	637.00
IUUC-Gga-040903	Gallus gallus	75.00	3.00e-178	617.00
IUUC-Ggo-044635	Gorilla gorilla	91.69	0.00e+00	738.00
IUUC-Hsa-046345	Homo sapiens	91.69	0.00e+00	738.00
IUUC-Itr-048220	Ictidomys tridecemlineatus	92.20	0.00e+00	714.00
IUUC-Lch-050599	Latimeria chalumnae	60.89	1.00e-139	489.00
IUUC-Loc-052378	Lepisosteus oculatus	63.73	1.00e-118	419.00
IUUC-Laf-053332	Loxodonta africana	93.14	0.00e+00	734.00
IUUC-Mcc-054705	Macaca mulatta	90.95	0.00e+00	734.00
IUUC-Meu-056825	Macropus eugenii	83.90	0.00e+00	699.00
IUUC-Mga-059528	Meleagris gallopavo	74.51	0.00e+00	627.00
IUUC-Mmr-060688	Microcebus murinus	93.40	0.00e+00	739.00
IUUC-Mdo-061882	Monodelphis domestica	84.11	0.00e+00	707.00
IUUC-Mmu-064352	Mus musculus	89.68	0.00e+00	742.00
IUUC-Mpu-066712	Mustela putorius furo	93.93	0.00e+00	681.00
IUUC-Mlu-068093	Myotis lucifugus	90.42	0.00e+00	715.00
IUUC-Nle-069310	Nomascus leucogenys	91.40	0.00e+00	730.00
IUUC-Ont-071759	Oreochromis niloticus	59.61	4.00e-111	394.00
IUUC-Oan-073673	Ornithorhynchus anatinus	80.24	0.00e+00	680.00
IUUC-Ola-087424	Oryzias latipes	59.09	1.00e-109	389.00
IUUC-Oga-088808	Otolemur garnettii	93.12	0.00e+00	740.00
IUUC-Oar-089553	Ovis aries	92.91	0.00e+00	736.00
IUUC-Ptr-090518	Pan troglodytes	91.44	0.00e+00	734.00
IUUC-Pan-092781	Papio anubis	90.71	0.00e+00	732.00
IUUC-Psi-093914	Pelodiscus sinensis	75.31	0.00e+00	627.00
IUUC-Pfo-096346	Poecilia formosa	57.41	1.00e-108	386.00
IUUC-Pca-100914	Procavia capensis	90.24	0.00e+00	745.00
IUUC-Pva-102728	Pteropus vampyrus	92.18	0.00e+00	730.00
IUUC-Rno-105922	Rattus norvegicus	88.94	0.00e+00	678.00
IUUC-Sha-107124	Sarcophilus harrisii	84.11	0.00e+00	710.00
IUUC-Sar-113607	Sorex araneus	90.22	0.00e+00	700.00
IUUC-Ssc-116355	Sus scrofa	94.59	0.00e+00	743.00
IUUC-Tgu-116476	Taeniopygia guttata	76.47	0.00e+00	634.00
IUUC-Tru-118737	Takifugu rubripes	59.93	3.00e-112	398.00
IUUC-Tsy-118908	Tarsius syrichta	93.15	0.00e+00	745.00
IUUC-Tbe-127258	Tupaia belangeri	95.35	0.00e+00	752.00
IUUC-Vpa-130138	Vicugna pacos	92.91	0.00e+00	737.00
IUUC-Xtr-132100	Xenopus tropicalis	59.56	3.00e-136	478.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence