iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022335

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02030365

Gene Name

TOPORS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000013705.3	ENSCPOT00000013844.2	ENSCPOP00000012342.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.20e-09	37.2	104	143

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl++f++  ++ +C H f++ C+q w      s++++ CPlC+
   Q: 104  CPICLDRFDNVSYLDRCLHKFCFRCVQEW------SKNKAECPLCK 143
           **********999999*************......**********7 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

QGSQPPPPGS PLSREEGDAP SPSPVAGGRR RSRRVRLRGC CRHRPSFPGR GELSSSASAG 60
PAPASSEIMA SAAKEFKMDN FSPKAGTSKL QQTVPADASP DSKCPICLDR FDNVSYLDRC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGGGTCCC AACCGCCGCC GCCGGGGTCC CCGCTGTCTC GCGAGGAGGG GGACGCGCCC 60
TCGCCCTCTC CGGTTGCTGG GGGTAGGCGG AGGAGTCGCC GGGTCCGCCT TCGCGGCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000930--C:gamma-tubulin complex
GO:0016607--C:nuclear speck
GO:0032391--C:photoreceptor connecting cilium
GO:0016605--C:PML body
GO:0000922--C:spindle pole
GO:0000151--C:ubiquitin ligase complex
GO:0003823--F:antigen binding
GO:0003677--F:DNA binding
GO:0019789--F:SUMO transferase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0051457--P:maintenance of protein location in nucleus
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0042127--P:regulation of cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000940	Aegilops tauschii	36.76	2.00e-09	55.80
IUUC-Aml-002240	Ailuropoda melanoleuca	83.18	0.00e+00	830.00
IUUC-Atr-002964	Amborella trichopoda	32.65	7.00e-11	60.80
IUUC-Apl-003666	Anas platyrhynchos	54.28	1.00e-137	483.00
IUUC-Aca-005305	Anolis carolinensis	57.20	5.00e-141	495.00
IUUC-Aly-005926	Arabidopsis lyrata	45.76	2.00e-10	59.70
IUUC-Ath-007299	Arabidopsis thaliana	45.76	8.00e-11	60.80
IUUC-Ame-011109	Astyanax mexicanus	53.98	3.00e-113	403.00
IUUC-Bta-012637	Bos taurus	82.89	0.00e+00	830.00
IUUC-Bdi-014270	Brachypodium distachyon	40.00	2.00e-11	62.80
IUUC-Bol-015147	Brassica oleracea	43.94	3.00e-09	57.40
IUUC-Bra-017451	Brassica rapa	31.25	2.00e-08	52.80
IUUC-Cel-018658	Caenorhabditis elegans	24.32	1.00e-06	48.50
IUUC-Cja-019105	Callithrix jacchus	86.45	0.00e+00	884.00
IUUC-Cfa-021203	Canis familiaris	84.10	0.00e+00	811.00
IUUC-Csa-023870	Chlorocebus sabaeus	86.65	0.00e+00	872.00
IUUC-Cho-024870	Choloepus hoffmanni	82.30	0.00e+00	780.00
IUUC-Cne-026788	Cryptococcus neoformans	33.85	4.00e-07	50.40
IUUC-Dre-027535	Danio rerio	52.93	1.00e-118	421.00
IUUC-Dno-028963	Dasypus novemcinctus	83.62	0.00e+00	801.00
IUUC-Dor-030239	Dipodomys ordii	84.43	0.00e+00	738.00
IUUC-Dme-031941	Drosophila melanogaster	32.76	2.00e-38	154.00
IUUC-Ete-032300	Echinops telfairi	77.14	0.00e+00	976.00
IUUC-Eca-033690	Equus caballus	85.17	0.00e+00	813.00
IUUC-Eeu-035257	Erinaceus europaeus	82.72	0.00e+00	806.00
IUUC-Fca-036383	Felis catus	82.72	0.00e+00	806.00
IUUC-Fal-037209	Ficedula albicollis	61.52	3.00e-153	536.00
IUUC-Gmo-039416	Gadus morhua	52.58	1.00e-115	409.00
IUUC-Gga-041267	Gallus gallus	65.18	1.00e-162	567.00
IUUC-Gac-042227	Gasterosteus aculeatus	47.50	6.00e-113	400.00
IUUC-Gma-043386	Glycine max	37.89	2.00e-12	65.90
IUUC-Ggo-044445	Gorilla gorilla	85.92	0.00e+00	880.00
IUUC-Hsa-045844	Homo sapiens	86.11	0.00e+00	882.00
IUUC-Hvu-047531	Hordeum vulgare	46.00	1.00e-10	57.40
IUUC-Itr-048818	Ictidomys tridecemlineatus	85.95	0.00e+00	846.00
IUUC-Lch-050031	Latimeria chalumnae	66.29	1.00e-161	563.00
IUUC-Lpe-051274	Leersia perrieri	37.74	1.00e-08	53.50
IUUC-Loc-052944	Lepisosteus oculatus	57.28	4.00e-140	491.00
IUUC-Laf-053820	Loxodonta africana	85.69	0.00e+00	778.00
IUUC-Mcc-054800	Macaca mulatta	86.65	0.00e+00	872.00
IUUC-Meu-056806	Macropus eugenii	70.91	7.00e-175	607.00
IUUC-Mtr-058378	Medicago truncatula	35.51	1.00e-11	63.50
IUUC-Mla-059017	Melampsora laricipopulina	36.07	3.00e-09	55.80
IUUC-Mvi-060417	Microbotryum violaceum	25.27	9.00e-17	82.40
IUUC-Mmr-061481	Microcebus murinus	85.95	0.00e+00	830.00
IUUC-Mdo-062219	Monodelphis domestica	79.84	1.00e-107	384.00
IUUC-Mmu-064138	Mus musculus	83.16	0.00e+00	766.00
IUUC-Mlu-067088	Myotis lucifugus	82.82	0.00e+00	830.00
IUUC-Nle-069862	Nomascus leucogenys	86.28	0.00e+00	891.00
IUUC-Opr-071076	Ochotona princeps	84.00	0.00e+00	730.00
IUUC-Ont-072225	Oreochromis niloticus	49.66	2.00e-107	383.00
IUUC-Oan-073069	Ornithorhynchus anatinus	66.11	7.00e-151	526.00
IUUC-Ocu-074826	Oryctolagus cuniculus	85.58	0.00e+00	834.00
IUUC-Oba-075429	Oryza barthii	37.68	1.00e-10	60.10
IUUC-Obr-076084	Oryza brachyantha	36.23	4.00e-10	58.50
IUUC-Ogl-077444	Oryza glaberrima	37.68	1.00e-10	60.10
IUUC-Ogu-078603	Oryza glumaepatula	37.68	1.00e-10	60.10
IUUC-Oin-079777	Oryza indica	37.68	1.00e-10	59.70
IUUC-Oni-082396	Oryza nivara	37.68	1.00e-10	60.10
IUUC-Opu-083698	Oryza punctata	36.62	7.00e-10	57.80
IUUC-Oru-084305	Oryza rufipogon	37.68	1.00e-10	60.10
IUUC-Ola-087377	Oryzias latipes	52.18	4.00e-106	377.00
IUUC-Oga-088059	Otolemur garnettii	83.18	0.00e+00	853.00
IUUC-Oar-089592	Ovis aries	83.81	0.00e+00	793.00
IUUC-Ptr-091233	Pan troglodytes	86.29	0.00e+00	883.00
IUUC-Pan-092743	Papio anubis	86.65	0.00e+00	872.00
IUUC-Psi-093669	Pelodiscus sinensis	57.51	0.00e+00	800.00
IUUC-Ppa-095668	Physcomitrella patens	27.30	3.00e-24	105.00
IUUC-Pfo-096706	Poecilia formosa	54.08	2.00e-105	377.00
IUUC-Pop-098813	Populus trichocarpa	23.96	7.00e-12	63.90
IUUC-Pca-100967	Procavia capensis	81.18	0.00e+00	717.00
IUUC-Ppe-101958	Prunus persica	38.96	4.00e-10	58.20
IUUC-Pva-102982	Pteropus vampyrus	85.58	0.00e+00	823.00
IUUC-Pgr-103551	Puccinia graminis	34.62	2.00e-09	55.80
IUUC-Ptt-103977	Puccinia triticina	32.79	5.00e-07	48.10
IUUC-Rno-105730	Rattus norvegicus	81.63	0.00e+00	735.00
IUUC-Sha-106588	Sarcophilus harrisii	68.20	2.00e-175	609.00
IUUC-Sja-107735	Schizosaccharomyces japonicus	34.21	8.00e-08	50.80
IUUC-Smo-109039	Selaginella moellendorffii	25.08	1.00e-16	80.90
IUUC-Sly-111835	Solanum lycopersicum	42.37	1.00e-08	55.50
IUUC-Stu-112898	Solanum tuberosum	42.37	1.00e-08	55.50
IUUC-Sar-113622	Sorex araneus	82.52	4.00e-143	502.00
IUUC-Sre-115041	Sporisorium reilianum	37.84	1.00e-09	57.40
IUUC-Ssc-115244	Sus scrofa	85.95	0.00e+00	778.00
IUUC-Tgu-117180	Taeniopygia guttata	62.02	2.00e-161	563.00
IUUC-Tru-118393	Takifugu rubripes	54.08	5.00e-118	418.00
IUUC-Tsy-119408	Tarsius syrichta	87.04	0.00e+00	842.00
IUUC-Tni-120664	Tetraodon nigroviridis	51.91	1.00e-119	424.00
IUUC-Tca-121712	Theobroma cacao	26.18	1.00e-16	80.10
IUUC-Tae-122787	Triticum aestivum	37.14	1.00e-10	60.10
IUUC-Tbe-127301	Tupaia belangeri	77.41	0.00e+00	723.00
IUUC-Ttr-128204	Tursiops truncatus	85.76	0.00e+00	862.00
IUUC-Uma-129420	Ustilago maydis	43.06	1.00e-09	57.40
IUUC-Vpa-130297	Vicugna pacos	85.95	0.00e+00	816.00
IUUC-Vvi-131157	Vitis vinifera	25.42	5.00e-17	81.60
IUUC-Xtr-132845	Xenopus tropicalis	65.90	1.00e-164	573.00
IUUC-Xma-133439	Xiphophorus maculatus	53.30	5.00e-107	382.00
IUUC-Yli-134652	Yarrowia lipolytica	38.78	5.00e-06	46.20

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence