iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098627

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01253536

Gene Name

RBCK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000010868.2	ENSPPYT00000012616.1	ENSPPYP00000012138.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	3.00e-11	42.7	194	220
ULD/UDP/UBQ/UBQ_Other	5.50e-06	26.3	60	121

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 3    aqWaCsaCTflNePeavkCemCsrpRg 29
            +W+C+ CTf+N+P +++CemC+r R+
   Q: 194  VGWQCPGCTFINKPTRPGCEMCCRARP 220
           68************************8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 4    tvksldgseltlk..vnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdg 64
            v++++  + t++  v p++tVa LK++++   g+pp  q+++++    +d  tL ++g++++
   Q: 60   SVEDAQMHTVTIWltVRPDMTVASLKDMVFLDYGFPPVLQQWVIQRLA-RDQETLHSHGVRQN 121
           5666665577777889****************************7755.**********9875 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MDEKTKKAEE MALSLTRAVA GGDEQVAMKC AIWLAEQRVP LSVQLKPEVS PTQDIRLWVS 60
VEDAQMHTVT IWLTVRPDMT VASLKDMVFL DYGFPPVLQQ WVIQRLARDQ ETLHSHGVRQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGTCCGG GGATCCGCGA TCAGCCCCGG AGGACGGGGT GGGGTCGCCC CAAACAGGAG 60
CGCCGAGACC GCTGGGACCC CGCACTCGGC GTCCGCCGCC GGCGGGTGGC CGGGCAGTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR002867--IBR_dom
IPR029071--Ubiquitin-rel_dom
IPR027370--Znf-RING_LisH
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00547--ZnF_RBZ

Gene Ontology

GO:0071797--C:LUBAC complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060546--P:negative regulation of necroptotic process
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0042346--P:positive regulation of NF-kappaB import into nucleus
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0097039--P:protein linear polyubiquitination
GO:0050852--P:T cell receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001540	Ailuropoda melanoleuca	92.35	0.00e+00	853.00
IUUC-Apl-003627	Anas platyrhynchos	61.54	1.00e-18	84.30
IUUC-Aca-004507	Anolis carolinensis	63.88	2.00e-151	528.00
IUUC-Ame-011008	Astyanax mexicanus	52.56	6.00e-141	494.00
IUUC-Bta-013247	Bos taurus	94.51	0.00e+00	903.00
IUUC-Bci-013637	Botrytis cinerea	25.85	1.00e-12	68.90
IUUC-Cja-018880	Callithrix jacchus	98.04	0.00e+00	935.00
IUUC-Cfa-020477	Canis familiaris	94.51	0.00e+00	905.00
IUUC-Cpo-021558	Cavia porcellus	90.20	0.00e+00	854.00
IUUC-Csa-024129	Chlorocebus sabaeus	98.63	0.00e+00	897.00
IUUC-Cin-025630	Ciona intestinalis	39.71	2.00e-80	293.00
IUUC-Csv-026069	Ciona savignyi	51.20	3.00e-72	264.00
IUUC-Dre-027591	Danio rerio	52.53	9.00e-140	490.00
IUUC-Dno-029015	Dasypus novemcinctus	92.16	0.00e+00	865.00
IUUC-Dor-030313	Dipodomys ordii	82.47	0.00e+00	733.00
IUUC-Ete-032908	Echinops telfairi	81.00	0.00e+00	754.00
IUUC-Eca-034295	Equus caballus	77.14	0.00e+00	718.00
IUUC-Eeu-034454	Erinaceus europaeus	86.10	1.00e-113	403.00
IUUC-Fca-036380	Felis catus	95.10	0.00e+00	908.00
IUUC-Fal-037440	Ficedula albicollis	56.90	3.00e-15	72.80
IUUC-Gmo-038561	Gadus morhua	53.39	6.00e-117	414.00
IUUC-Gga-040198	Gallus gallus	37.62	6.00e-27	114.00
IUUC-Gac-041319	Gasterosteus aculeatus	52.34	2.00e-135	476.00
IUUC-Ggo-044456	Gorilla gorilla	68.65	1.00e-158	552.00
IUUC-Hsa-045738	Homo sapiens	99.80	0.00e+00	897.00
IUUC-Itr-049042	Ictidomys tridecemlineatus	92.75	0.00e+00	862.00
IUUC-Lch-050269	Latimeria chalumnae	44.55	5.00e-112	398.00
IUUC-Loc-052776	Lepisosteus oculatus	48.82	3.00e-134	472.00
IUUC-Laf-054269	Loxodonta africana	91.57	0.00e+00	877.00
IUUC-Mcc-055669	Macaca mulatta	99.41	0.00e+00	910.00
IUUC-Mga-059615	Meleagris gallopavo	54.69	1.00e-17	80.50
IUUC-Mmr-061562	Microcebus murinus	93.60	0.00e+00	773.00
IUUC-Mdo-062263	Monodelphis domestica	77.91	0.00e+00	744.00
IUUC-Mmu-064325	Mus musculus	90.98	0.00e+00	840.00
IUUC-Mpu-066385	Mustela putorius furo	94.51	0.00e+00	902.00
IUUC-Mlu-067000	Myotis lucifugus	91.18	0.00e+00	857.00
IUUC-Nle-069812	Nomascus leucogenys	99.02	0.00e+00	905.00
IUUC-Opr-070575	Ochotona princeps	93.63	8.00e-107	380.00
IUUC-Ont-072405	Oreochromis niloticus	52.10	2.00e-136	479.00
IUUC-Ocu-074358	Oryctolagus cuniculus	80.61	0.00e+00	763.00
IUUC-Ola-086403	Oryzias latipes	53.01	2.00e-138	486.00
IUUC-Oga-087986	Otolemur garnettii	93.53	0.00e+00	849.00
IUUC-Oar-089600	Ovis aries	92.16	0.00e+00	894.00
IUUC-Ptr-091224	Pan troglodytes	99.61	0.00e+00	895.00
IUUC-Pan-092739	Papio anubis	99.61	0.00e+00	913.00
IUUC-Pma-094407	Petromyzon marinus	43.18	8.00e-109	387.00
IUUC-Pfo-097161	Poecilia formosa	52.89	7.00e-132	464.00
IUUC-Pca-100641	Procavia capensis	92.03	0.00e+00	816.00
IUUC-Pva-102670	Pteropus vampyrus	91.76	0.00e+00	861.00
IUUC-Pte-104234	Pyrenophora teres	25.41	3.00e-12	66.20
IUUC-Rno-105504	Rattus norvegicus	90.78	0.00e+00	837.00
IUUC-Sha-107342	Sarcophilus harrisii	77.91	0.00e+00	761.00
IUUC-Sar-113425	Sorex araneus	88.13	3.00e-113	401.00
IUUC-Ssc-115904	Sus scrofa	93.64	7.00e-90	322.00
IUUC-Tru-118096	Takifugu rubripes	51.54	2.00e-136	479.00
IUUC-Tni-119873	Tetraodon nigroviridis	49.71	1.00e-136	479.00
IUUC-Tbe-127578	Tupaia belangeri	90.78	0.00e+00	688.00
IUUC-Ttr-129107	Tursiops truncatus	94.31	0.00e+00	852.00
IUUC-Vpa-130353	Vicugna pacos	95.55	4.00e-125	441.00
IUUC-Xtr-132168	Xenopus tropicalis	42.01	6.00e-92	331.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence