iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107586

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01066963

Gene Name

NSMCE2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000002119.1	ENSSHAT00000002414.1	ENSSHAP00000002388.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.00e-09	38.5	87	162

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlp.sGitydrssIekwlasggk.....tcPvtrqpl...teedlvPnltlrrliqawce 70
             f+CpI+   M+ Pv  + +G+ty+ ++I++ ++s++k      cP+ + +    + +dlv   +lrr i++++ 
   Q: 87   TNFICPITQLEMKKPVKNKvCGHTYEEEAIRRIIESKHKrkkkaCCPKVGCSHadvKLTDLVQDVVLRRAIENHRR 162
           57********************************99999999998998665443338999***********99876 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MCLIFFFQVK DKNYQNVTPN LKALAEEKLV ALKSNNKESD LKKDHRFVQF RQQLRDVKKQ 60
CGLLVDPTDD DSEEQIDEDM IVTQSQTNFI CPITQLEMKK PVKNKVCGHT YEEEAIRRII 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGATAGTA AAGCCAGAAA TCCTTATTCT TAAATCTGTG AATCAAACTA AAGTGTTTTT 60
TTTTATTTTT TATTTTTTTG TTTTTTAAGA ATGAATTTAC TCAGTTTCCA TAAATGTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR026846--Nse2(Mms21)
IPR003613--Ubox_domain
IPR004181--Znf_MIZ
IPR013083--Znf_RING/FYVE/PHD

Pfam

PF11789--zf-Nse

SMART

SM00504--Ubox

Gene Ontology

GO:0000781--C:chromosome, telomeric region
GO:0016605--C:PML body
GO:0030915--C:Smc5-Smc6 complex
GO:0019789--F:SUMO transferase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0090398--P:cellular senescence
GO:0000724--P:double-strand break repair via homologous recombination
GO:0034184--P:positive regulation of maintenance of mitotic sister chromatid cohesion
GO:0045842--P:positive regulation of mitotic metaphase/anaphase transition
GO:0000722--P:telomere maintenance via recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001627	Ailuropoda melanoleuca	64.24	9.00e-46	176.00
IUUC-Atr-002438	Amborella trichopoda	36.11	1.00e-06	46.60
IUUC-Apl-004091	Anas platyrhynchos	63.55	2.00e-29	120.00
IUUC-Aca-004433	Anolis carolinensis	47.80	3.00e-39	154.00
IUUC-Ath-007424	Arabidopsis thaliana	26.92	2.00e-07	49.30
IUUC-Ago-007852	Ashbya gossypii	30.11	5.00e-09	53.90
IUUC-Ate-010326	Aspergillus terreus	32.56	8.00e-03	36.20
IUUC-Ame-010902	Astyanax mexicanus	43.41	5.00e-27	114.00
IUUC-Bgr-012088	Blumeria graminis	28.05	2.00e-04	39.70
IUUC-Bta-013397	Bos taurus	67.36	9.00e-38	149.00
IUUC-Bci-013738	Botrytis cinerea	26.53	8.00e-04	38.10
IUUC-Cja-019246	Callithrix jacchus	67.36	7.00e-47	180.00
IUUC-Cpo-021670	Cavia porcellus	67.36	1.00e-38	152.00
IUUC-Csa-023982	Chlorocebus sabaeus	63.33	4.00e-43	167.00
IUUC-Cin-025127	Ciona intestinalis	34.92	1.00e-13	69.70
IUUC-Cgl-026430	Colletotrichum gloeosporioides	31.17	8.00e-07	47.80
IUUC-Cne-026806	Cryptococcus neoformans	28.79	1.00e-09	57.00
IUUC-Cme-027175	Cyanidioschyzon merolae	29.58	2.00e-05	42.70
IUUC-Dre-028325	Danio rerio	43.36	1.00e-26	112.00
IUUC-Dno-029735	Dasypus novemcinctus	68.75	4.00e-57	214.00
IUUC-Dor-030454	Dipodomys ordii	40.91	1.00e-19	89.70
IUUC-Dse-031273	Dothistroma septosporum	31.17	1.00e-03	38.10
IUUC-Dme-031971	Drosophila melanogaster	27.64	2.00e-08	52.00
IUUC-Ete-032838	Echinops telfairi	70.59	1.00e-29	122.00
IUUC-Eca-034371	Equus caballus	65.97	3.00e-53	201.00
IUUC-Eeu-035258	Erinaceus europaeus	70.54	3.00e-31	127.00
IUUC-Fca-035576	Felis catus	66.67	1.00e-44	172.00
IUUC-Fal-037038	Ficedula albicollis	47.80	2.00e-40	158.00
IUUC-Fox-037843	Fusarium oxysporum	29.73	3.00e-04	39.70
IUUC-Fso-038272	Fusarium solani	37.50	2.00e-04	40.40
IUUC-Ggr-040059	Gaeumannomyces graminis	30.38	8.00e-06	45.10
IUUC-Gga-040737	Gallus gallus	45.36	2.00e-31	129.00
IUUC-Gac-042591	Gasterosteus aculeatus	43.07	3.00e-23	101.00
IUUC-Gma-043177	Glycine max	29.33	2.00e-09	55.80
IUUC-Ggo-045206	Gorilla gorilla	63.19	3.00e-43	168.00
IUUC-Hsa-046704	Homo sapiens	63.19	3.00e-43	168.00
IUUC-Itr-048972	Ictidomys tridecemlineatus	79.35	3.00e-33	133.00
IUUC-Kpa-049181	Komagataella pastoris	31.40	1.00e-07	50.40
IUUC-Loc-052687	Lepisosteus oculatus	43.06	6.00e-26	110.00
IUUC-Lma-053255	Leptosphaeria maculans	29.41	8.00e-04	38.50
IUUC-Laf-054270	Loxodonta africana	68.06	5.00e-47	180.00
IUUC-Mcc-054757	Macaca mulatta	63.89	1.00e-42	165.00
IUUC-Mor-057028	Magnaporthe oryzae	30.56	8.00e-06	44.70
IUUC-Mpo-057462	Magnaporthe poae	31.65	5.00e-07	48.50
IUUC-Mtr-058011	Medicago truncatula	29.63	1.00e-08	53.50
IUUC-Mga-059215	Meleagris gallopavo	62.07	6.00e-30	122.00
IUUC-Mvi-060511	Microbotryum violaceum	30.26	2.00e-05	43.50
IUUC-Mmr-061584	Microcebus murinus	69.44	5.00e-36	144.00
IUUC-Mdo-061863	Monodelphis domestica	85.80	1.00e-77	282.00
IUUC-Mmu-064413	Mus musculus	66.67	2.00e-46	178.00
IUUC-Mpu-066092	Mustela putorius furo	51.16	5.00e-43	167.00
IUUC-Mlu-068198	Myotis lucifugus	66.23	2.00e-56	212.00
IUUC-Nle-070109	Nomascus leucogenys	63.89	7.00e-45	173.00
IUUC-Opr-070540	Ochotona princeps	65.35	9.00e-26	110.00
IUUC-Ont-071575	Oreochromis niloticus	41.26	2.00e-27	115.00
IUUC-Oan-072777	Ornithorhynchus anatinus	73.63	7.00e-25	104.00
IUUC-Ocu-074730	Oryctolagus cuniculus	66.67	4.00e-47	181.00
IUUC-Obr-076506	Oryza brachyantha	30.00	2.00e-07	48.50
IUUC-Oga-087925	Otolemur garnettii	68.06	8.00e-39	153.00
IUUC-Oar-090138	Ovis aries	53.49	3.00e-35	141.00
IUUC-Ptr-091582	Pan troglodytes	63.19	3.00e-43	168.00
IUUC-Pan-092890	Papio anubis	63.89	8.00e-43	166.00
IUUC-Psi-093714	Pelodiscus sinensis	52.05	5.00e-41	160.00
IUUC-Pma-094198	Petromyzon marinus	33.58	4.00e-20	89.70
IUUC-Pab-098005	Pongo abelii	62.50	3.00e-43	168.00
IUUC-Pca-100368	Procavia capensis	80.85	1.00e-33	135.00
IUUC-Ppe-101873	Prunus persica	30.36	2.00e-07	48.90
IUUC-Pva-102951	Pteropus vampyrus	64.58	5.00e-51	193.00
IUUC-Pte-104390	Pyrenophora teres	38.57	2.00e-05	43.50
IUUC-Pyt-104633	Pyrenophora triticirepentis	38.57	6.00e-05	41.60
IUUC-Rno-105346	Rattus norvegicus	66.67	2.00e-46	178.00
IUUC-Sja-107983	Schizosaccharomyces japonicus	34.31	4.00e-10	58.20
IUUC-Spo-108327	Schizosaccharomyces pombe	25.26	6.00e-05	40.80
IUUC-Ssl-108555	Sclerotinia sclerotiorum	32.05	8.00e-05	41.60
IUUC-Sly-111667	Solanum lycopersicum	30.30	1.00e-04	40.00
IUUC-Sar-113609	Sorex araneus	66.67	3.00e-36	144.00
IUUC-Sre-115187	Sporisorium reilianum	26.53	2.00e-06	46.60
IUUC-Tgu-116472	Taeniopygia guttata	49.03	2.00e-38	152.00
IUUC-Tru-117771	Takifugu rubripes	39.72	6.00e-22	97.40
IUUC-Tni-119821	Tetraodon nigroviridis	50.56	1.00e-22	99.80
IUUC-Tca-121272	Theobroma cacao	27.63	3.00e-05	42.40
IUUC-Tre-122049	Trichoderma reesei	29.63	4.00e-06	45.40
IUUC-Tvi-122642	Trichoderma virens	31.67	7.00e-06	44.70
IUUC-Tme-126988	Tuber melanosporum	34.48	7.00e-07	48.10
IUUC-Tbe-127676	Tupaia belangeri	68.75	4.00e-30	124.00
IUUC-Ttr-128602	Tursiops truncatus	68.06	2.00e-48	185.00
IUUC-Uma-129520	Ustilago maydis	29.33	4.00e-05	42.00
IUUC-Vpa-130510	Vicugna pacos	67.12	5.00e-47	180.00
IUUC-Vvi-131486	Vitis vinifera	27.92	2.00e-07	49.30

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence