iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-061826

UUCD1 version

UUC-MoD-00799

Ensembl Protein ID

ENSMODP00000010123.2

UniProt Accession

F7ELL1; F7ELL1_MONDO

Protein Name

Uncharacterized protein

Gene Name

RNF121

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000008145.3	ENSMODT00000010318.3	ENSMODP00000010123.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.60e-07	31.9	226	276

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..........kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C + +          ++ ++ l+C+Hvfh+ C+  w    +   k+++CP+C+
   Q: 226  CAVCGQQIfvdvneegiiEN-TYRLSCNHVFHEFCIRGW----CIVGKKQTCPYCK 276
           9***9988888887777655.777***************....889999******7 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

GKMAAVVEVE VGGAAGEREL EEVDLSDLSP EERWRIEHAR MHAKHRGHEA MHAEMVLILI 60
ATLVVAQLLL VQWKQRHPRS YNMVTLFQMW VVPLYFTVKL HWWRFLEIWV LFSTTAFVTS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGAAGATGG CGGCGGTGGT GGAGGTGGAG GTTGGAGGCG CCGCCGGCGA GCGGGAGCTA 60
GAGGAGGTAA GAGGCTCGGG GGGACCCACA GAGAGCCAGA GGAGCGGTCC CTGGGGGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002350	Ailuropoda melanoleuca	95.15	1.00e-167	582.00
IUUC-Atr-002646	Amborella trichopoda	37.68	3.00e-06	47.00
IUUC-Apl-003882	Anas platyrhynchos	86.82	6.00e-138	483.00
IUUC-Aca-004343	Anolis carolinensis	91.30	2.00e-23	100.00
IUUC-Aly-005550	Arabidopsis lyrata	37.10	2.00e-06	47.40
IUUC-Ath-007362	Arabidopsis thaliana	34.38	1.00e-06	48.10
IUUC-Ame-010680	Astyanax mexicanus	83.13	1.00e-157	548.00
IUUC-Bta-013045	Bos taurus	96.60	4.00e-160	556.00
IUUC-Bci-013624	Botrytis cinerea	36.21	2.00e-07	51.20
IUUC-Cel-018296	Caenorhabditis elegans	50.95	4.00e-96	344.00
IUUC-Cja-019866	Callithrix jacchus	94.82	1.00e-167	582.00
IUUC-Cfa-021176	Canis familiaris	93.93	2.00e-166	578.00
IUUC-Cpo-022268	Cavia porcellus	93.85	1.00e-164	572.00
IUUC-Cre-022649	Chlamydomonas reinhardtii	42.23	3.00e-52	197.00
IUUC-Csa-023727	Chlorocebus sabaeus	95.47	3.00e-168	583.00
IUUC-Cho-025016	Choloepus hoffmanni	95.18	4.00e-169	586.00
IUUC-Cin-025281	Ciona intestinalis	64.57	2.00e-123	434.00
IUUC-Csv-026338	Ciona savignyi	63.64	5.00e-113	400.00
IUUC-Dre-027836	Danio rerio	81.43	1.00e-138	485.00
IUUC-Dno-029737	Dasypus novemcinctus	93.93	2.00e-166	578.00
IUUC-Dor-031070	Dipodomys ordii	87.21	5.00e-147	513.00
IUUC-Dme-031867	Drosophila melanogaster	59.94	8.00e-111	393.00
IUUC-Ete-032964	Echinops telfairi	86.82	2.00e-159	555.00
IUUC-Eca-034398	Equus caballus	95.47	2.00e-168	584.00
IUUC-Eeu-035318	Erinaceus europaeus	61.96	2.00e-115	408.00
IUUC-Fca-035807	Felis catus	95.13	1.00e-165	575.00
IUUC-Fal-036721	Ficedula albicollis	95.49	2.00e-155	541.00
IUUC-Gmo-039699	Gadus morhua	87.34	3.00e-146	511.00
IUUC-Gga-040840	Gallus gallus	95.90	2.00e-158	550.00
IUUC-Gac-042639	Gasterosteus aculeatus	82.23	5.00e-147	513.00
IUUC-Ggo-045576	Gorilla gorilla	95.41	4.00e-166	577.00
IUUC-Hsa-046468	Homo sapiens	95.15	7.00e-168	582.00
IUUC-Itr-048638	Ictidomys tridecemlineatus	95.12	2.00e-140	491.00
IUUC-Lch-050207	Latimeria chalumnae	81.82	6.00e-140	489.00
IUUC-Loc-052172	Lepisosteus oculatus	88.27	1.00e-156	545.00
IUUC-Laf-053879	Loxodonta africana	94.55	2.00e-169	587.00
IUUC-Mcc-055492	Macaca mulatta	95.47	3.00e-168	583.00
IUUC-Meu-055976	Macropus eugenii	83.01	7.00e-136	476.00
IUUC-Mga-059989	Meleagris gallopavo	93.97	2.00e-166	577.00
IUUC-Mmr-060894	Microcebus murinus	95.47	3.00e-168	583.00
IUUC-Mmu-063717	Mus musculus	95.13	3.00e-167	580.00
IUUC-Mpu-066826	Mustela putorius furo	95.47	4.00e-168	583.00
IUUC-Mlu-068081	Myotis lucifugus	91.61	2.00e-165	574.00
IUUC-Nle-069734	Nomascus leucogenys	95.47	3.00e-168	583.00
IUUC-Opr-070379	Ochotona princeps	92.28	5.00e-161	560.00
IUUC-Ont-071855	Oreochromis niloticus	83.13	1.00e-147	515.00
IUUC-Ocu-074363	Oryctolagus cuniculus	95.18	1.00e-168	585.00
IUUC-Ola-086489	Oryzias latipes	81.63	1.00e-145	508.00
IUUC-Oga-088323	Otolemur garnettii	95.44	2.00e-165	574.00
IUUC-Oar-090243	Ovis aries	95.50	3.00e-169	587.00
IUUC-Ptr-091374	Pan troglodytes	95.15	7.00e-168	582.00
IUUC-Pan-092115	Papio anubis	95.47	3.00e-168	583.00
IUUC-Psi-093658	Pelodiscus sinensis	92.69	8.00e-154	536.00
IUUC-Pfo-097261	Poecilia formosa	81.63	7.00e-146	509.00
IUUC-Pab-098579	Pongo abelii	95.15	7.00e-168	582.00
IUUC-Pca-100119	Procavia capensis	90.35	1.00e-154	538.00
IUUC-Pva-102111	Pteropus vampyrus	95.42	4.00e-166	577.00
IUUC-Rno-105364	Rattus norvegicus	94.86	8.00e-169	585.00
IUUC-Sha-107005	Sarcophilus harrisii	97.75	1.00e-172	598.00
IUUC-Stu-112248	Solanum tuberosum	39.66	1.00e-06	48.10
IUUC-Sar-113163	Sorex araneus	95.79	3.00e-168	584.00
IUUC-Ssc-115633	Sus scrofa	93.08	7.00e-167	579.00
IUUC-Tgu-116869	Taeniopygia guttata	96.60	3.00e-160	557.00
IUUC-Tru-118217	Takifugu rubripes	80.65	9.00e-153	532.00
IUUC-Tsy-119308	Tarsius syrichta	94.82	3.00e-167	580.00
IUUC-Tni-119882	Tetraodon nigroviridis	81.98	9.00e-154	535.00
IUUC-Tbe-127912	Tupaia belangeri	70.33	3.00e-106	377.00
IUUC-Ttr-129087	Tursiops truncatus	95.42	1.00e-166	578.00
IUUC-Vpa-130785	Vicugna pacos	89.71	1.00e-155	542.00
IUUC-Xtr-132801	Xenopus tropicalis	94.43	2.00e-156	545.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence