iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012510

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

PDZ and LIM domain protein 2

Genbank Nucleotide ID

BC102452

Gene Name

PDLIM2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000007369.5	ENSBTAT00000009697.5	ENSBTAP00000009697.5

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	75.84	2.00e-119	426.00	IUUC-Hsa-045868
E3 activity/Other	73.74	4.00e-119	425.00	IUUC-Mmu-063244

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Bos taurus

Functional Description
(View)

Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity (By similarity).

Protein Sequence
(Fasta)

MALTVDVVGP APWGFRISGG RDFHTPIMVT KVTERGKAEA ADLRPGDIIV SINGESAKDM 60
LHAEAQSKIR QSPSPLRLQL DRPQAASPGQ ANGESSLEVL ATRFQSSRRT HTDSQASLSP 120

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Nucleotide Sequence
(Fasta)

AGGCAGACGG CGGCGGCGGC GGCGGGAGCG GCGGCTTCTC CTTGCCTCCC TCCTTCCCTT 60
CCCTTCGCTC TCGGGCCTTG CCGCCCAGCC CGACAGGTGA GCGGGAGCCA GGTGAGCGCA 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0440--LIM domain
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031847--DUF4749
IPR001478--PDZ
IPR001781--Znf_LIM

PROSITE

PS00478--LIM_DOMAIN_1
PS50023--LIM_DOMAIN_2
PS50106--PDZ

Pfam

PF15936--DUF4749
PF00412--LIM
PF00595--PDZ

SMART

SM00132--LIM
SM00228--PDZ

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005856--C:cytoskeleton
GO:0008270--F:zinc ion binding

KEGG

bta:512907

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001484	Ailuropoda melanoleuca	75.64	2.00e-132	464.00
IUUC-Aca-004512	Anolis carolinensis	47.90	3.00e-82	298.00
IUUC-Ame-011626	Astyanax mexicanus	54.87	5.00e-32	131.00
IUUC-Bdi-014056	Brachypodium distachyon	31.82	1.10e-02	34.70
IUUC-Cja-019248	Callithrix jacchus	76.40	2.00e-124	438.00
IUUC-Cfa-020352	Canis familiaris	76.26	1.00e-129	456.00
IUUC-Cpo-021995	Cavia porcellus	69.36	3.00e-110	391.00
IUUC-Csa-024190	Chlorocebus sabaeus	77.25	2.00e-121	429.00
IUUC-Dre-027418	Danio rerio	54.84	2.00e-38	152.00
IUUC-Dor-030439	Dipodomys ordii	58.19	9.00e-61	227.00
IUUC-Dme-031753	Drosophila melanogaster	42.65	1.00e-11	64.30
IUUC-Eca-034183	Equus caballus	83.62	1.00e-133	468.00
IUUC-Eeu-034958	Erinaceus europaeus	67.89	1.00e-77	283.00
IUUC-Fca-035680	Felis catus	79.39	2.00e-133	468.00
IUUC-Fal-037626	Ficedula albicollis	31.75	1.00e-05	45.10
IUUC-Gmo-038558	Gadus morhua	53.85	7.00e-39	154.00
IUUC-Gac-041738	Gasterosteus aculeatus	41.44	2.00e-69	256.00
IUUC-Ggo-044609	Gorilla gorilla	76.69	7.00e-123	433.00
IUUC-Hsa-045868	Homo sapiens	76.97	4.00e-120	425.00
IUUC-Itr-048876	Ictidomys tridecemlineatus	76.82	2.00e-124	438.00
IUUC-Loc-052212	Lepisosteus oculatus	44.17	1.00e-73	270.00
IUUC-Laf-053824	Loxodonta africana	74.58	4.00e-123	434.00
IUUC-Mcc-054962	Macaca mulatta	77.25	2.00e-121	429.00
IUUC-Meu-056007	Macropus eugenii	53.55	1.00e-39	157.00
IUUC-Mmr-060607	Microcebus murinus	77.09	2.00e-124	438.00
IUUC-Mdo-062935	Monodelphis domestica	73.53	3.00e-53	202.00
IUUC-Mmu-063244	Mus musculus	71.79	4.00e-120	424.00
IUUC-Mpu-065888	Mustela putorius furo	78.65	3.00e-120	424.00
IUUC-Mlu-067124	Myotis lucifugus	77.37	3.00e-137	481.00
IUUC-Ncr-068674	Neurospora crassa	40.35	3.00e-07	50.80
IUUC-Nle-069063	Nomascus leucogenys	74.50	1.00e-85	308.00
IUUC-Opr-071221	Ochotona princeps	71.75	7.00e-103	367.00
IUUC-Ont-072000	Oreochromis niloticus	42.46	1.00e-70	259.00
IUUC-Oan-073012	Ornithorhynchus anatinus	56.20	2.00e-84	305.00
IUUC-Ocu-074376	Oryctolagus cuniculus	69.83	9.00e-113	399.00
IUUC-Ola-086915	Oryzias latipes	42.66	5.00e-71	261.00
IUUC-Oga-088393	Otolemur garnettii	76.26	2.00e-120	425.00
IUUC-Oar-089421	Ovis aries	95.98	3.00e-170	590.00
IUUC-Ptr-091089	Pan troglodytes	76.44	4.00e-108	384.00
IUUC-Pan-092163	Papio anubis	76.97	1.00e-115	409.00
IUUC-Psi-093043	Pelodiscus sinensis	44.99	5.00e-65	241.00
IUUC-Pno-094933	Phaeosphaeria nodorum	27.87	4.00e-04	40.00
IUUC-Pfo-096885	Poecilia formosa	56.69	9.00e-40	157.00
IUUC-Pab-097988	Pongo abelii	76.44	2.00e-107	382.00
IUUC-Pca-100131	Procavia capensis	78.53	3.00e-121	428.00
IUUC-Pva-102706	Pteropus vampyrus	72.14	3.00e-115	409.00
IUUC-Ptt-104003	Puccinia triticina	32.65	5.70e-01	29.30
IUUC-Pte-104256	Pyrenophora teres	39.34	7.00e-07	49.30
IUUC-Pyt-104720	Pyrenophora triticirepentis	39.34	2.00e-06	47.00
IUUC-Rno-104992	Rattus norvegicus	72.91	1.00e-116	412.00
IUUC-Sha-107463	Sarcophilus harrisii	61.68	6.00e-71	260.00
IUUC-Sar-113038	Sorex araneus	40.24	5.00e-16	79.70
IUUC-Sre-115199	Sporisorium reilianum	29.31	4.10e-02	33.90
IUUC-Ssc-115811	Sus scrofa	82.73	5.00e-137	480.00
IUUC-Tbe-127240	Tupaia belangeri	59.16	2.00e-73	269.00
IUUC-Ttr-128236	Tursiops truncatus	64.25	5.00e-102	364.00
IUUC-Uma-129653	Ustilago maydis	29.31	8.40e-02	33.10
IUUC-Vpa-130569	Vicugna pacos	60.89	1.00e-95	342.00
IUUC-Xma-133476	Xiphophorus maculatus	56.69	2.00e-40	159.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence