iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004818

Ensembl Protein ID

ENSACAP00000008212.2

UniProt Accession

H9GDU0; H9GDU0_ANOCA

Protein Name

Uncharacterized protein

Gene Name

CRK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000008373.3	ENSACAT00000008389.3	ENSACAP00000008212.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.40e-16	60.1	54	109

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           e v++l+d++++++++L +kkGd++++   e+ +e W+++ ++ eg+rG++P  +vek 
   Q: 54   EFVRALFDFQGNDEEDLPFKKGDILRI--REKPEEQWWNA-EDGEGRRGMIPVPYVEKC 109
           6799***********************..5999******9.59*************986 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

RFRIGDQEFD SLPSLLEFYK IHYLDTTTLI EPVSKAKHRG SGDLQQPRAE EEAEFVRALF 60
DFQGNDEEDL PFKKGDILRI REKPEEQWWN AEDGEGRRGM IPVPYVEKCR PAPHPIVGGP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGATTCCGGA TCGGGGACCA GGAGTTTGAC TCCCTGCCGT CTCTGCTGGA ATTCTACAAG 60
ATCCACTACC TGGACACTAC CACCCTGATC GAGCCGGTCT CCAAGGCCAA GCACCGCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50002--SH3

Pfam

PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0070062--C:extracellular exosome
GO:0048013--P:ephrin receptor signaling pathway
GO:0009967--P:positive regulation of signal transduction
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:0032956--P:regulation of actin cytoskeleton organization
GO:0043087--P:regulation of GTPase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001192	Ailuropoda melanoleuca	78.26	4.00e-97	347.00
IUUC-Apl-003225	Anas platyrhynchos	75.32	2.00e-93	334.00
IUUC-Bta-012320	Bos taurus	78.26	5.00e-97	347.00
IUUC-Cja-019935	Callithrix jacchus	78.35	8.00e-98	349.00
IUUC-Cfa-021221	Canis familiaris	78.26	1.00e-96	346.00
IUUC-Cpo-021592	Cavia porcellus	77.92	2.00e-96	345.00
IUUC-Cho-024775	Choloepus hoffmanni	79.22	9.00e-99	352.00
IUUC-Dre-027390	Danio rerio	64.58	6.00e-82	296.00
IUUC-Dno-029847	Dasypus novemcinctus	78.26	5.00e-97	347.00
IUUC-Dor-030360	Dipodomys ordii	77.92	2.00e-95	342.00
IUUC-Ete-032604	Echinops telfairi	77.49	7.00e-95	339.00
IUUC-Eca-033233	Equus caballus	78.35	5.00e-98	350.00
IUUC-Eeu-034642	Erinaceus europaeus	78.79	3.00e-97	347.00
IUUC-Fca-035955	Felis catus	78.79	1.00e-97	348.00
IUUC-Fal-037152	Ficedula albicollis	78.95	3.00e-98	351.00
IUUC-Gga-040731	Gallus gallus	75.76	2.00e-96	345.00
IUUC-Gac-041627	Gasterosteus aculeatus	64.83	8.00e-82	296.00
IUUC-Ggo-045475	Gorilla gorilla	78.26	5.00e-97	347.00
IUUC-Hsa-046008	Homo sapiens	78.26	5.00e-97	347.00
IUUC-Lch-050509	Latimeria chalumnae	73.16	6.00e-93	333.00
IUUC-Laf-053896	Loxodonta africana	78.35	1.00e-97	348.00
IUUC-Mcc-055280	Macaca mulatta	78.26	5.00e-97	347.00
IUUC-Meu-056783	Macropus eugenii	77.49	2.00e-95	341.00
IUUC-Mga-059345	Meleagris gallopavo	76.96	1.00e-96	345.00
IUUC-Mvi-060518	Microbotryum violaceum	36.54	3.00e-09	55.80
IUUC-Mdo-062691	Monodelphis domestica	75.76	4.00e-93	333.00
IUUC-Mmu-063691	Mus musculus	77.83	1.00e-96	346.00
IUUC-Mpu-065737	Mustela putorius furo	78.26	5.00e-97	347.00
IUUC-Mlu-067005	Myotis lucifugus	76.52	8.00e-96	343.00
IUUC-Nle-070154	Nomascus leucogenys	77.92	3.00e-97	347.00
IUUC-Opr-071114	Ochotona princeps	78.35	8.00e-98	349.00
IUUC-Oga-088266	Otolemur garnettii	78.26	3.00e-97	347.00
IUUC-Oar-089221	Ovis aries	78.26	6.00e-97	347.00
IUUC-Ptr-091463	Pan troglodytes	78.26	8.00e-97	346.00
IUUC-Pan-092242	Papio anubis	78.26	5.00e-97	347.00
IUUC-Psi-093287	Pelodiscus sinensis	77.49	9.00e-97	345.00
IUUC-Pca-101068	Procavia capensis	78.26	5.00e-97	347.00
IUUC-Ptt-103815	Puccinia triticina	39.66	5.00e-10	58.20
IUUC-Rno-105288	Rattus norvegicus	78.70	2.00e-97	348.00
IUUC-Sha-106511	Sarcophilus harrisii	55.98	2.00e-52	198.00
IUUC-Sar-113453	Sorex araneus	77.92	5.00e-97	347.00
IUUC-Tgu-116926	Taeniopygia guttata	77.19	3.00e-94	337.00
IUUC-Tru-118656	Takifugu rubripes	69.17	3.00e-86	311.00
IUUC-Tni-120229	Tetraodon nigroviridis	62.14	9.00e-78	283.00
IUUC-Tbe-127436	Tupaia belangeri	76.21	1.00e-90	325.00
IUUC-Ttr-129109	Tursiops truncatus	78.35	3.00e-97	347.00
IUUC-Vpa-130527	Vicugna pacos	77.83	6.00e-95	340.00
IUUC-Xtr-131808	Xenopus tropicalis	78.79	4.00e-97	347.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence