iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-001192

Ensembl Protein ID

ENSAMEP00000008621.1

UniProt Accession

G1LNJ3; G1LNJ3_AILME

Genbank Protein ID

ENSAMEP00000008621

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01083579

Gene Name

CRK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000008194.1	ENSAMET00000008985.1	ENSAMEP00000008621.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.50e-18	66.6	133	188

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            e+v++l+d++++++++L +kkGd++++   ++ +e W+++ ++ egkrG++P  +vek
   Q: 133  AEYVRALFDFNGNDEEDLPFKKGDILRI--RDKPEEQWWNA-EDSEGKRGMIPVPYVEK 188
           689*************************..6999******9.5**************98 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

QAGDDSEERS SWYWGRLSRQ EAVALLQGQR HGVFLVRDSS TSPGDYVLSV SENSRVSHYI 60
INSSGPRPSV PPSPAQPPPG VSPSRLRIGD QEFDSLPALL EFYKIHYLDT TTLIEPVSRS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGCGGGGG ACGACTCGGA GGAGCGGAGT AGCTGGTACT GGGGGCGGTT GAGCCGGCAG 60
GAGGCGGTGG CGCTCTTGCA GGGCCAGCGG CACGGGGTGT TTCTGGTGCG GGACTCGAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0070062--C:extracellular exosome
GO:0048013--P:ephrin receptor signaling pathway
GO:0009967--P:positive regulation of signal transduction
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:0032956--P:regulation of actin cytoskeleton organization
GO:0043087--P:regulation of GTPase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003225	Anas platyrhynchos	92.00	9.00e-123	432.00
IUUC-Aca-004818	Anolis carolinensis	78.35	4.00e-93	333.00
IUUC-Ame-011721	Astyanax mexicanus	67.19	3.00e-116	411.00
IUUC-Bta-012320	Bos taurus	99.67	2.00e-160	557.00
IUUC-Cel-018307	Caenorhabditis elegans	30.23	3.00e-27	115.00
IUUC-Cja-019935	Callithrix jacchus	96.32	2.00e-165	574.00
IUUC-Cfa-021221	Canis familiaris	100.00	2.00e-160	558.00
IUUC-Cpo-021592	Cavia porcellus	86.82	3.00e-138	484.00
IUUC-Csa-024128	Chlorocebus sabaeus	99.49	1.00e-97	348.00
IUUC-Cho-024775	Choloepus hoffmanni	94.70	1.00e-159	555.00
IUUC-Dre-027390	Danio rerio	68.11	2.00e-117	415.00
IUUC-Dno-029847	Dasypus novemcinctus	99.67	2.00e-160	557.00
IUUC-Dor-030360	Dipodomys ordii	89.63	3.00e-153	534.00
IUUC-Ete-032604	Echinops telfairi	96.86	3.00e-126	443.00
IUUC-Eca-033233	Equus caballus	97.99	2.00e-161	561.00
IUUC-Eeu-034642	Erinaceus europaeus	97.31	3.00e-128	450.00
IUUC-Fca-035955	Felis catus	99.56	1.00e-131	461.00
IUUC-Fal-037152	Ficedula albicollis	86.83	3.00e-143	500.00
IUUC-Gmo-038849	Gadus morhua	67.52	8.00e-116	409.00
IUUC-Gga-040861	Gallus gallus	84.00	4.00e-148	517.00
IUUC-Gac-041627	Gasterosteus aculeatus	66.46	1.00e-117	416.00
IUUC-Ggo-045475	Gorilla gorilla	99.67	2.00e-160	557.00
IUUC-Hsa-046008	Homo sapiens	99.67	2.00e-160	557.00
IUUC-Itr-048906	Ictidomys tridecemlineatus	99.22	5.00e-131	459.00
IUUC-Lch-050509	Latimeria chalumnae	82.30	2.00e-145	508.00
IUUC-Loc-052229	Lepisosteus oculatus	73.41	7.00e-106	376.00
IUUC-Laf-053896	Loxodonta africana	95.36	1.00e-164	572.00
IUUC-Mcc-055280	Macaca mulatta	99.67	2.00e-160	557.00
IUUC-Meu-056783	Macropus eugenii	96.86	8.00e-127	445.00
IUUC-Mga-059345	Meleagris gallopavo	92.38	6.00e-124	436.00
IUUC-Mdo-062691	Monodelphis domestica	88.45	3.00e-152	530.00
IUUC-Mmu-063691	Mus musculus	99.33	4.00e-160	556.00
IUUC-Mpu-065737	Mustela putorius furo	100.00	2.00e-160	557.00
IUUC-Mlu-067005	Myotis lucifugus	96.32	1.00e-155	542.00
IUUC-Nle-070154	Nomascus leucogenys	99.56	2.00e-131	461.00
IUUC-Opr-071114	Ochotona princeps	97.99	1.00e-166	578.00
IUUC-Ont-071696	Oreochromis niloticus	69.26	9.00e-113	399.00
IUUC-Oan-072967	Ornithorhynchus anatinus	92.16	1.00e-129	455.00
IUUC-Ocu-074025	Oryctolagus cuniculus	98.48	3.00e-96	343.00
IUUC-Oga-088266	Otolemur garnettii	98.33	2.00e-159	554.00
IUUC-Oar-089221	Ovis aries	98.00	7.00e-156	542.00
IUUC-Ptr-091463	Pan troglodytes	94.98	3.00e-148	517.00
IUUC-Pan-092242	Papio anubis	99.33	2.00e-160	557.00
IUUC-Psi-093287	Pelodiscus sinensis	94.64	6.00e-127	446.00
IUUC-Pfo-097378	Poecilia formosa	66.24	1.00e-108	385.00
IUUC-Pab-097823	Pongo abelii	99.49	1.00e-97	348.00
IUUC-Pca-101068	Procavia capensis	99.67	2.00e-160	557.00
IUUC-Rno-105288	Rattus norvegicus	99.33	5.00e-160	556.00
IUUC-Sar-113453	Sorex araneus	84.28	1.00e-143	501.00
IUUC-Tgu-116926	Taeniopygia guttata	86.67	2.00e-147	514.00
IUUC-Tru-118656	Takifugu rubripes	67.28	1.00e-118	419.00
IUUC-Tni-120497	Tetraodon nigroviridis	69.93	3.00e-113	401.00
IUUC-Tbe-127436	Tupaia belangeri	94.65	1.00e-141	495.00
IUUC-Ttr-129109	Tursiops truncatus	100.00	9.00e-131	458.00
IUUC-Vpa-130527	Vicugna pacos	99.33	3.00e-158	550.00
IUUC-Xtr-131808	Xenopus tropicalis	85.33	2.00e-148	518.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence