iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-021221

Ensembl Protein ID

ENSCAFP00000028257.3

UniProt Accession

E2QWD3; E2QWD3_CANLF

Genbank Protein ID

ENSCAFP00000028257

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03006692

Gene Name

CRK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000019157.3	ENSCAFT00000030413.3	ENSCAFP00000028257.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.60e-18	65.6	215	270

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            e+v++l+d++++++++L +kkGd++++   ++ +e W+++ ++ egkrG++P  +vek
   Q: 215  AEYVRALFDFNGNDEEDLPFKKGDILRI--RDKPEEQWWNA-EDSEGKRGMIPVPYVEK 270
           689*************************..6999******9.5**************98 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MRSAHPSCPL PFSPWRVAVP FPASSRGQGA RHFRWGRPAA AAAISGTAVK LRPEPVRWAA 60
GAGAGGARVP AAAQRVGAEA AMAGNFDSEE RSSWYWGRLS RQEAVALLQG QRHGVFLVRD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGACTTGAAA GACTCAATCC AGAGAACTCC TGGCTTGGCA CATTCTGCTC TCTCTGTCTT 60
GCATGCTCTT CCCCTACTGG CCATTCAACA TTCAGCTCAA GCCACCTCCT CTGGTAGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0070062--C:extracellular exosome
GO:0048013--P:ephrin receptor signaling pathway
GO:0009967--P:positive regulation of signal transduction
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:0032956--P:regulation of actin cytoskeleton organization
GO:0043087--P:regulation of GTPase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001192	Ailuropoda melanoleuca	100.00	3.00e-160	557.00
IUUC-Apl-003225	Anas platyrhynchos	92.00	2.00e-122	431.00
IUUC-Aca-004818	Anolis carolinensis	78.35	1.00e-92	332.00
IUUC-Ame-011721	Astyanax mexicanus	67.70	2.00e-119	421.00
IUUC-Bta-012320	Bos taurus	99.67	1.00e-163	568.00
IUUC-Cel-018307	Caenorhabditis elegans	30.33	2.00e-27	116.00
IUUC-Cja-019935	Callithrix jacchus	96.38	2.00e-168	584.00
IUUC-Cpo-021592	Cavia porcellus	86.49	1.00e-137	481.00
IUUC-Csa-024128	Chlorocebus sabaeus	99.51	8.00e-101	359.00
IUUC-Cho-024775	Choloepus hoffmanni	95.07	5.00e-162	563.00
IUUC-Dre-027390	Danio rerio	68.29	3.00e-120	424.00
IUUC-Dno-029847	Dasypus novemcinctus	99.67	1.00e-163	568.00
IUUC-Dor-030360	Dipodomys ordii	89.80	4.00e-156	543.00
IUUC-Ete-032604	Echinops telfairi	96.86	9.00e-126	442.00
IUUC-Eca-033233	Equus caballus	98.03	1.00e-164	572.00
IUUC-Eeu-034642	Erinaceus europaeus	97.31	9.00e-128	448.00
IUUC-Fca-035955	Felis catus	99.56	5.00e-132	462.00
IUUC-Fal-037152	Ficedula albicollis	86.83	6.00e-143	499.00
IUUC-Gmo-038849	Gadus morhua	67.72	4.00e-118	417.00
IUUC-Gga-040861	Gallus gallus	83.93	2.00e-150	525.00
IUUC-Gac-041627	Gasterosteus aculeatus	66.67	2.00e-120	425.00
IUUC-Ggo-045475	Gorilla gorilla	99.67	1.00e-163	568.00
IUUC-Hsa-046008	Homo sapiens	99.67	1.00e-163	568.00
IUUC-Itr-048906	Ictidomys tridecemlineatus	99.23	5.00e-134	469.00
IUUC-Lch-050509	Latimeria chalumnae	82.58	2.00e-148	518.00
IUUC-Loc-052229	Lepisosteus oculatus	73.90	6.00e-109	386.00
IUUC-Laf-053896	Loxodonta africana	95.44	2.00e-167	581.00
IUUC-Mcc-055280	Macaca mulatta	99.67	1.00e-163	568.00
IUUC-Meu-056783	Macropus eugenii	96.86	1.00e-126	445.00
IUUC-Mga-059345	Meleagris gallopavo	92.38	1.00e-123	434.00
IUUC-Mdo-062691	Monodelphis domestica	88.64	5.00e-155	540.00
IUUC-Mmu-063691	Mus musculus	99.34	3.00e-163	567.00
IUUC-Mpu-065737	Mustela putorius furo	100.00	1.00e-163	568.00
IUUC-Mlu-067005	Myotis lucifugus	96.38	9.00e-159	552.00
IUUC-Nle-070154	Nomascus leucogenys	99.56	8.00e-132	462.00
IUUC-Opr-071114	Ochotona princeps	98.03	9.00e-176	608.00
IUUC-Ont-071696	Oreochromis niloticus	69.75	8.00e-116	409.00
IUUC-Oan-072967	Ornithorhynchus anatinus	92.31	1.00e-132	465.00
IUUC-Ocu-074025	Oryctolagus cuniculus	98.52	2.00e-99	354.00
IUUC-Olo-080293	Oryza longistaminata	40.00	1.70e+00	26.20
IUUC-Oga-088266	Otolemur garnettii	98.36	1.00e-162	565.00
IUUC-Oar-089221	Ovis aries	98.03	5.00e-159	553.00
IUUC-Ptr-091463	Pan troglodytes	95.07	2.00e-151	527.00
IUUC-Pan-092242	Papio anubis	99.34	1.00e-163	568.00
IUUC-Psi-093287	Pelodiscus sinensis	94.64	1.00e-126	445.00
IUUC-Pfo-097378	Poecilia formosa	66.46	7.00e-111	393.00
IUUC-Pab-097823	Pongo abelii	99.51	8.00e-101	359.00
IUUC-Pca-101068	Procavia capensis	99.67	1.00e-163	568.00
IUUC-Ptt-103815	Puccinia triticina	37.93	2.00e-09	56.20
IUUC-Rno-105288	Rattus norvegicus	99.34	4.00e-163	566.00
IUUC-Sar-113453	Sorex araneus	84.54	3.00e-146	511.00
IUUC-Tgu-116926	Taeniopygia guttata	84.59	8.00e-150	522.00
IUUC-Tru-118656	Takifugu rubripes	67.78	1.00e-121	429.00
IUUC-Tni-120497	Tetraodon nigroviridis	70.42	1.00e-116	412.00
IUUC-Tbe-127436	Tupaia belangeri	94.74	9.00e-145	506.00
IUUC-Ttr-129109	Tursiops truncatus	100.00	4.00e-131	459.00
IUUC-Vpa-130527	Vicugna pacos	99.34	2.00e-161	561.00
IUUC-Xtr-131808	Xenopus tropicalis	85.57	1.00e-151	528.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence