iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048906

Ensembl Protein ID

ENSSTOP00000004574.2

UniProt Accession

I3M5G8; I3M5G8_ICTTR

Genbank Protein ID

ENSSTOP00000004574

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01051100

Gene Name

CRK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000005107.2	ENSSTOT00000005095.2	ENSSTOP00000004574.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.30e-13	49.4	134	189

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            e+v++l+d++++++++L +kkGd++++   ++ +e W+++ ++ egkrG++P  +vek
   Q: 134  AEYVRALFDFNGNDEEDLPFKKGDILRI--RDKPEEQWWNA-EDSEGKRGMIPVPYVEK 189
           689*************************..6999******9.5**************98 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MAGNFDSEER SSWYWGRLSR QEAVALLQGQ RHGVFLVRDS STSPGDYVLS VSENSRVSHY 60
IINSSGPRPP VPPSPAQPPP GVSPSRLRIG DQEFDSLPAL LEFYKIHYLD TTTLIEPVSR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCGGGCGC TGCTGTGAGG GTGAGACCCG AGCCGGTCCG CTGGGCGGCG GGCGCCCGGG 60
CTGGAGTGTC GCGCGTGGCG GCGGCGGCCC AGCGTGTTGG CGCGGAGGTG GCCATGGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0070062--C:extracellular exosome
GO:0048013--P:ephrin receptor signaling pathway
GO:0009967--P:positive regulation of signal transduction
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:0032956--P:regulation of actin cytoskeleton organization
GO:0043087--P:regulation of GTPase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001192	Ailuropoda melanoleuca	99.22	8.00e-131	459.00
IUUC-Apl-003225	Anas platyrhynchos	89.56	2.00e-93	334.00
IUUC-Ame-010854	Astyanax mexicanus	65.70	3.00e-98	350.00
IUUC-Bta-012320	Bos taurus	99.62	2.00e-134	471.00
IUUC-Cja-019935	Callithrix jacchus	95.40	3.00e-138	484.00
IUUC-Cfa-021221	Canis familiaris	99.23	5.00e-134	470.00
IUUC-Cpo-021592	Cavia porcellus	84.19	8.00e-109	386.00
IUUC-Csa-024128	Chlorocebus sabaeus	99.51	9.00e-100	355.00
IUUC-Cho-024775	Choloepus hoffmanni	98.08	2.00e-133	467.00
IUUC-Dre-027390	Danio rerio	67.99	1.00e-96	345.00
IUUC-Dno-029847	Dasypus novemcinctus	99.62	2.00e-134	471.00
IUUC-Dor-030360	Dipodomys ordii	87.74	3.00e-127	447.00
IUUC-Ete-032604	Echinops telfairi	97.78	3.00e-99	353.00
IUUC-Eca-033233	Equus caballus	97.70	2.00e-133	468.00
IUUC-Eeu-034642	Erinaceus europaeus	96.11	6.00e-99	352.00
IUUC-Fca-035955	Felis catus	98.90	8.00e-102	362.00
IUUC-Fal-037152	Ficedula albicollis	84.87	1.00e-112	398.00
IUUC-Gmo-038849	Gadus morhua	65.57	2.00e-96	344.00
IUUC-Gga-040861	Gallus gallus	81.30	1.00e-121	428.00
IUUC-Gac-041627	Gasterosteus aculeatus	65.83	2.00e-99	355.00
IUUC-Ggo-045475	Gorilla gorilla	99.62	2.00e-134	471.00
IUUC-Hsa-046008	Homo sapiens	99.62	2.00e-134	471.00
IUUC-Lch-050509	Latimeria chalumnae	79.40	1.00e-120	425.00
IUUC-Loc-052229	Lepisosteus oculatus	73.63	4.00e-109	387.00
IUUC-Laf-053896	Loxodonta africana	93.94	2.00e-137	481.00
IUUC-Mcc-055280	Macaca mulatta	99.62	2.00e-134	471.00
IUUC-Meu-056783	Macropus eugenii	96.11	4.00e-98	350.00
IUUC-Mga-059345	Meleagris gallopavo	90.61	2.00e-95	340.00
IUUC-Mdo-062691	Monodelphis domestica	86.42	6.00e-125	439.00
IUUC-Mmu-063691	Mus musculus	99.23	6.00e-134	469.00
IUUC-Mpu-065737	Mustela putorius furo	99.23	2.00e-134	471.00
IUUC-Mlu-067005	Myotis lucifugus	96.17	5.00e-130	456.00
IUUC-Nle-070154	Nomascus leucogenys	98.90	1.00e-101	361.00
IUUC-Opr-071114	Ochotona princeps	97.70	8.00e-137	479.00
IUUC-Oan-072967	Ornithorhynchus anatinus	93.10	1.00e-131	462.00
IUUC-Ocu-074025	Oryctolagus cuniculus	98.53	2.00e-98	350.00
IUUC-Ola-087265	Oryzias latipes	67.02	6.00e-96	343.00
IUUC-Oga-088266	Otolemur garnettii	98.08	2.00e-133	468.00
IUUC-Oar-089221	Ovis aries	97.71	1.00e-129	455.00
IUUC-Ptr-091463	Pan troglodytes	94.25	2.00e-122	431.00
IUUC-Pan-092242	Papio anubis	99.23	2.00e-134	471.00
IUUC-Psi-093287	Pelodiscus sinensis	92.82	2.00e-97	348.00
IUUC-Pab-097823	Pongo abelii	99.51	9.00e-100	355.00
IUUC-Pca-101068	Procavia capensis	99.62	2.00e-134	471.00
IUUC-Ptt-103815	Puccinia triticina	37.93	3.00e-09	55.50
IUUC-Rno-105288	Rattus norvegicus	99.62	2.00e-134	471.00
IUUC-Sar-113453	Sorex araneus	81.61	2.00e-117	414.00
IUUC-Tgu-116926	Taeniopygia guttata	84.73	2.00e-121	427.00
IUUC-Tru-117806	Takifugu rubripes	66.78	3.00e-95	341.00
IUUC-Tni-120497	Tetraodon nigroviridis	67.79	2.00e-92	332.00
IUUC-Tbe-127436	Tupaia belangeri	93.87	2.00e-116	411.00
IUUC-Ttr-129109	Tursiops truncatus	99.44	1.00e-101	361.00
IUUC-Vpa-130527	Vicugna pacos	99.62	2.00e-134	471.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence