iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053896

Ensembl Protein ID

ENSLAFP00000020783.1

UniProt Accession

G3TYX5; G3TYX5_LOXAF

Protein Name

Uncharacterized protein

Gene Name

CRK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000010559.2	ENSLAFT00000036418.1	ENSLAFP00000020783.1
ENSLAFG00000010559.2	ENSLAFT00000010559.2	ENSLAFP00000008842.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.80e-18	66.6	137	192

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            e+v++l+d++++++++L +kkGd++++   ++ +e W+++ ++ egkrG++P  +vek
   Q: 137  AEYVRALFDFNGNDEEDLPFKKGDILRI--RDKPEEQWWNA-EDSEGKRGMIPVPYVEK 192
           689*************************..6999******9.5**************98 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MAGNFDSEER SSWYWGRLSR QEAVALLQGQ RHGVFLVRDS STSPGDYVLS VSENSRVSHY 60
IINKCADSEP HSQSPAQRST PPPGVSPSRL RIGDQEFDSL PALLEFYKIH YLDTTTLIEP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGGCA ACTTCGACTC GGAGGAGCGG AGTAGTTGGT ACTGGGGGCG GTTGAGCCGG 60
CAGGAGGCGG TGGCGCTGTT GCAGGGCCAG CGGCACGGGG TGTTCCTGGT GCGGGACTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0070062--C:extracellular exosome
GO:0048013--P:ephrin receptor signaling pathway
GO:0009967--P:positive regulation of signal transduction
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:0032956--P:regulation of actin cytoskeleton organization
GO:0043087--P:regulation of GTPase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001192	Ailuropoda melanoleuca	94.70	2.00e-159	554.00
IUUC-Apl-003225	Anas platyrhynchos	92.00	1.00e-122	431.00
IUUC-Aca-004818	Anolis carolinensis	78.35	4.00e-93	333.00
IUUC-Ame-011721	Astyanax mexicanus	67.40	3.00e-120	424.00
IUUC-Bta-012320	Bos taurus	95.11	6.00e-163	566.00
IUUC-Cel-018307	Caenorhabditis elegans	30.69	5.00e-27	114.00
IUUC-Cja-019935	Callithrix jacchus	94.46	1.00e-169	588.00
IUUC-Cfa-021221	Canis familiaris	94.79	1.00e-162	565.00
IUUC-Cpo-021592	Cavia porcellus	85.52	2.00e-140	491.00
IUUC-Csa-024128	Chlorocebus sabaeus	91.75	2.00e-100	357.00
IUUC-Cho-024775	Choloepus hoffmanni	93.81	1.00e-162	565.00
IUUC-Cin-025128	Ciona intestinalis	45.90	2.00e-73	268.00
IUUC-Csv-026340	Ciona savignyi	45.03	4.00e-66	244.00
IUUC-Dre-027390	Danio rerio	68.31	4.00e-121	427.00
IUUC-Dno-029847	Dasypus novemcinctus	95.11	6.00e-163	566.00
IUUC-Dor-030360	Dipodomys ordii	88.93	1.00e-155	541.00
IUUC-Dme-031600	Drosophila melanogaster	45.12	1.00e-66	245.00
IUUC-Ete-032604	Echinops telfairi	96.86	3.00e-126	443.00
IUUC-Eca-033233	Equus caballus	93.81	2.00e-162	564.00
IUUC-Eeu-034642	Erinaceus europaeus	97.31	4.00e-128	449.00
IUUC-Fca-035955	Felis catus	99.56	4.00e-132	462.00
IUUC-Fal-037152	Ficedula albicollis	85.92	5.00e-143	499.00
IUUC-Gmo-038849	Gadus morhua	67.40	1.00e-120	425.00
IUUC-Gga-040861	Gallus gallus	83.06	8.00e-151	525.00
IUUC-Gac-041627	Gasterosteus aculeatus	65.74	5.00e-121	426.00
IUUC-Ggo-045475	Gorilla gorilla	95.11	6.00e-163	566.00
IUUC-Hsa-046008	Homo sapiens	95.11	6.00e-163	566.00
IUUC-Itr-048906	Ictidomys tridecemlineatus	93.94	2.00e-133	468.00
IUUC-Lch-050509	Latimeria chalumnae	82.32	7.00e-151	526.00
IUUC-Loc-052229	Lepisosteus oculatus	73.36	2.00e-109	388.00
IUUC-Mcc-055280	Macaca mulatta	95.11	6.00e-163	566.00
IUUC-Meu-056783	Macropus eugenii	96.86	1.00e-126	445.00
IUUC-Mga-059345	Meleagris gallopavo	92.38	7.00e-124	435.00
IUUC-Mdo-062691	Monodelphis domestica	88.35	2.00e-154	538.00
IUUC-Mmu-063691	Mus musculus	94.79	1.00e-162	565.00
IUUC-Mpu-065737	Mustela putorius furo	94.79	6.00e-163	566.00
IUUC-Mlu-067005	Myotis lucifugus	91.86	4.00e-158	550.00
IUUC-Nle-070154	Nomascus leucogenys	99.56	7.00e-132	462.00
IUUC-Opr-071114	Ochotona princeps	95.11	3.00e-170	590.00
IUUC-Ont-071696	Oreochromis niloticus	68.77	7.00e-116	409.00
IUUC-Oan-072967	Ornithorhynchus anatinus	89.35	7.00e-133	466.00
IUUC-Ocu-074025	Oryctolagus cuniculus	90.78	6.00e-99	352.00
IUUC-Olo-080293	Oryza longistaminata	40.00	1.70e+00	26.20
IUUC-Ola-087265	Oryzias latipes	66.67	9.00e-98	349.00
IUUC-Oga-088266	Otolemur garnettii	93.81	4.00e-162	563.00
IUUC-Oar-089221	Ovis aries	93.51	3.00e-158	550.00
IUUC-Ptr-091463	Pan troglodytes	90.55	4.00e-151	526.00
IUUC-Pan-092242	Papio anubis	95.11	6.00e-163	566.00
IUUC-Psi-093287	Pelodiscus sinensis	94.64	8.00e-127	445.00
IUUC-Pma-094340	Petromyzon marinus	58.75	1.00e-100	359.00
IUUC-Pfo-097378	Poecilia formosa	66.15	3.00e-112	397.00
IUUC-Pab-097823	Pongo abelii	91.75	2.00e-100	357.00
IUUC-Pca-101068	Procavia capensis	95.11	6.00e-163	566.00
IUUC-Rno-105288	Rattus norvegicus	94.79	2.00e-162	564.00
IUUC-Sar-113453	Sorex araneus	83.71	9.00e-146	509.00
IUUC-Tgu-116926	Taeniopygia guttata	83.71	4.00e-150	523.00
IUUC-Tru-118656	Takifugu rubripes	67.17	4.00e-122	430.00
IUUC-Tni-120497	Tetraodon nigroviridis	68.69	2.00e-117	415.00
IUUC-Tbe-127436	Tupaia belangeri	89.90	4.00e-144	503.00
IUUC-Ttr-129109	Tursiops truncatus	100.00	4.00e-131	459.00
IUUC-Vpa-130527	Vicugna pacos	94.79	8.00e-161	559.00
IUUC-Xtr-131808	Xenopus tropicalis	84.42	3.00e-152	530.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence