iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059345

Ensembl Protein ID

ENSMGAP00000004524.2

UniProt Accession

G1MZN9; G1MZN9_MELGA

Protein Name

Uncharacterized protein

Gene Name

CRK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000004706.2	ENSMGAT00000005242.2	ENSMGAP00000004524.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.90e-19	67.3	59	114

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           e+v++l+d+++++d++L +kkGd++++   ++ +e W+++ ++ egkrG++P  +vek 
   Q: 59   EYVRALFDFNGNDDEDLPFKKGDILKI--RDKPEEQWWNA-EDSEGKRGMIPVPYVEKC 114
           79*************************..6999******9.5**************986 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

FLFSGLNPTR FRIGDQEFDS LPSLLEFYKI HYLDTTTLIE PVSRSRQNSG VILRQEEVEY 60
VRALFDFNGN DDEDLPFKKG DILKIRDKPE EQWWNAEDSE GKRGMIPVPY VEKCRPSSAS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCTCTTTT CAGGGTTGAA TCCCACCAGA TTTCGAATAG GTGACCAGGA GTTTGATTCT 60
TTGCCATCTT TACTGGAATT CTACAAAATA CACTATTTGG ACACTACAAC CTTGATAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50002--SH3

Pfam

PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0070062--C:extracellular exosome
GO:0048013--P:ephrin receptor signaling pathway
GO:0009967--P:positive regulation of signal transduction
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:0032956--P:regulation of actin cytoskeleton organization
GO:0043087--P:regulation of GTPase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001192	Ailuropoda melanoleuca	93.55	2.00e-121	427.00
IUUC-Apl-003225	Anas platyrhynchos	94.25	4.00e-124	436.00
IUUC-Aca-004818	Anolis carolinensis	71.19	1.00e-92	331.00
IUUC-Bta-012320	Bos taurus	93.55	2.00e-121	427.00
IUUC-Cja-019935	Callithrix jacchus	92.34	3.00e-123	434.00
IUUC-Cfa-021221	Canis familiaris	93.55	3.00e-121	427.00
IUUC-Cpo-021592	Cavia porcellus	93.27	5.00e-124	436.00
IUUC-Cho-024775	Choloepus hoffmanni	93.58	2.00e-122	431.00
IUUC-Dno-029847	Dasypus novemcinctus	93.55	2.00e-121	427.00
IUUC-Dor-030360	Dipodomys ordii	91.44	3.00e-120	424.00
IUUC-Ete-032604	Echinops telfairi	89.64	8.00e-119	418.00
IUUC-Eca-033233	Equus caballus	91.93	2.00e-123	434.00
IUUC-Eeu-034642	Erinaceus europaeus	90.99	2.00e-120	423.00
IUUC-Fca-035955	Felis catus	91.93	5.00e-123	432.00
IUUC-Fal-037152	Ficedula albicollis	96.41	2.00e-127	447.00
IUUC-Gga-040731	Gallus gallus	98.64	1.00e-129	455.00
IUUC-Ggo-045475	Gorilla gorilla	93.55	2.00e-121	427.00
IUUC-Hsa-046008	Homo sapiens	93.55	2.00e-121	427.00
IUUC-Itr-048906	Ictidomys tridecemlineatus	92.00	7.00e-93	332.00
IUUC-Lch-050509	Latimeria chalumnae	87.44	3.00e-117	414.00
IUUC-Laf-053896	Loxodonta africana	92.38	9.00e-124	435.00
IUUC-Mcc-055280	Macaca mulatta	93.55	2.00e-121	427.00
IUUC-Meu-056783	Macropus eugenii	92.79	8.00e-123	431.00
IUUC-Mdo-062691	Monodelphis domestica	92.83	6.00e-122	429.00
IUUC-Mmu-063691	Mus musculus	93.09	4.00e-121	426.00
IUUC-Mpu-065737	Mustela putorius furo	93.55	2.00e-121	427.00
IUUC-Mlu-067005	Myotis lucifugus	91.71	1.00e-118	418.00
IUUC-Nle-070154	Nomascus leucogenys	91.93	7.00e-123	432.00
IUUC-Opr-071114	Ochotona princeps	91.48	2.00e-122	431.00
IUUC-Oan-072967	Ornithorhynchus anatinus	91.06	3.00e-95	340.00
IUUC-Oga-088266	Otolemur garnettii	93.55	1.00e-121	428.00
IUUC-Oar-089221	Ovis aries	93.09	5.00e-121	426.00
IUUC-Ptr-091463	Pan troglodytes	93.55	5.00e-121	426.00
IUUC-Pan-092242	Papio anubis	93.55	2.00e-121	427.00
IUUC-Psi-093287	Pelodiscus sinensis	95.52	2.00e-126	443.00
IUUC-Pca-101068	Procavia capensis	93.55	2.00e-121	427.00
IUUC-Rno-105288	Rattus norvegicus	93.09	6.00e-121	426.00
IUUC-Sar-113453	Sorex araneus	91.44	8.00e-121	426.00
IUUC-Tgu-116926	Taeniopygia guttata	94.57	2.00e-122	431.00
IUUC-Tbe-127436	Tupaia belangeri	88.48	2.00e-104	371.00
IUUC-Ttr-129109	Tursiops truncatus	92.34	7.00e-123	432.00
IUUC-Vpa-130527	Vicugna pacos	93.09	2.00e-119	421.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence