iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067005

Ensembl Protein ID

ENSMLUP00000002474.2

UniProt Accession

G1NYI2; G1NYI2_MYOLU

Genbank Protein ID

ENSMLUP00000002474

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02038123

Gene Name

CRK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000002723.2	ENSMLUT00000002721.2	ENSMLUP00000002474.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.70e-18	65.3	135	189

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           e+v++l+d++++++++L +kkGd++++   ++ +e W+++ ++ egkrG++P  +vek
   Q: 135  EYVRALFDFNGNDEEDLPFKKGDILKI--RDKPEEQWWNA-EDMEGKRGMIPVPYVEK 189
           799************************..6999******9.5**************98 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MAGNFDSEER SSWYWGRLSR QEAVSMLQGQ RHGVFLVRDS STSPGDYVLS VSENSRVSHY 60
IINSSGPRPP VPPSPAQPPP GVSPSRLRIG DQEFDSLPAL LEFYKIHYLD TTTLIEPVSR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGGCA ACTTCGACTC GGAGGAGAGG AGTAGCTGGT ACTGGGGGCG GTTGAGCCGG 60
CAGGAGGCGG TGTCGATGTT GCAGGGCCAG CGGCACGGGG TGTTCCTGGT GCGGGACTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0070062--C:extracellular exosome
GO:0048013--P:ephrin receptor signaling pathway
GO:0009967--P:positive regulation of signal transduction
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:0032956--P:regulation of actin cytoskeleton organization
GO:0043087--P:regulation of GTPase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001192	Ailuropoda melanoleuca	96.32	1.00e-155	542.00
IUUC-Apl-003225	Anas platyrhynchos	90.22	1.00e-119	421.00
IUUC-Aca-004818	Anolis carolinensis	76.62	8.00e-92	329.00
IUUC-Ame-011721	Astyanax mexicanus	67.72	4.00e-118	417.00
IUUC-Bta-012320	Bos taurus	96.71	4.00e-159	553.00
IUUC-Cel-018307	Caenorhabditis elegans	30.67	2.00e-27	115.00
IUUC-Cja-019935	Callithrix jacchus	93.09	5.00e-163	566.00
IUUC-Cfa-021221	Canis familiaris	96.38	7.00e-159	553.00
IUUC-Cpo-021592	Cavia porcellus	83.78	1.00e-133	468.00
IUUC-Cho-024775	Choloepus hoffmanni	94.74	2.00e-157	548.00
IUUC-Dre-027390	Danio rerio	68.42	4.00e-119	420.00
IUUC-Dno-029847	Dasypus novemcinctus	96.71	4.00e-159	553.00
IUUC-Dor-030360	Dipodomys ordii	86.51	6.00e-152	529.00
IUUC-Ete-032604	Echinops telfairi	93.72	2.00e-122	431.00
IUUC-Eca-033233	Equus caballus	95.07	3.00e-158	550.00
IUUC-Eeu-034642	Erinaceus europaeus	93.72	1.00e-123	435.00
IUUC-Fca-035955	Felis catus	95.98	6.00e-127	446.00
IUUC-Fal-037152	Ficedula albicollis	85.05	7.00e-138	482.00
IUUC-Gmo-038849	Gadus morhua	67.09	2.00e-116	412.00
IUUC-Gga-040861	Gallus gallus	83.28	2.00e-149	521.00
IUUC-Gac-041627	Gasterosteus aculeatus	65.42	3.00e-119	421.00
IUUC-Ggo-045475	Gorilla gorilla	96.71	4.00e-159	553.00
IUUC-Hsa-046008	Homo sapiens	96.71	4.00e-159	553.00
IUUC-Itr-048906	Ictidomys tridecemlineatus	96.17	6.00e-130	456.00
IUUC-Lch-050509	Latimeria chalumnae	80.32	4.00e-146	510.00
IUUC-Loc-052229	Lepisosteus oculatus	71.69	3.00e-106	377.00
IUUC-Laf-053896	Loxodonta africana	91.86	4.00e-162	563.00
IUUC-Mcc-055280	Macaca mulatta	96.71	4.00e-159	553.00
IUUC-Meu-056783	Macropus eugenii	93.27	2.00e-122	431.00
IUUC-Mga-059345	Meleagris gallopavo	90.58	4.00e-121	426.00
IUUC-Mdo-062691	Monodelphis domestica	86.04	3.00e-150	523.00
IUUC-Mmu-063691	Mus musculus	96.38	8.00e-159	552.00
IUUC-Mpu-065737	Mustela putorius furo	96.38	4.00e-159	553.00
IUUC-Nle-070154	Nomascus leucogenys	96.43	1.00e-127	448.00
IUUC-Opr-071114	Ochotona princeps	95.07	1.00e-161	562.00
IUUC-Ont-071696	Oreochromis niloticus	69.21	8.00e-115	406.00
IUUC-Oan-072967	Ornithorhynchus anatinus	90.00	1.00e-128	451.00
IUUC-Oga-088266	Otolemur garnettii	96.38	8.00e-159	552.00
IUUC-Oar-089221	Ovis aries	95.08	2.00e-154	537.00
IUUC-Ptr-091463	Pan troglodytes	92.11	6.00e-147	513.00
IUUC-Pan-092242	Papio anubis	96.38	4.00e-159	553.00
IUUC-Psi-093287	Pelodiscus sinensis	91.52	2.00e-122	431.00
IUUC-Pfo-097378	Poecilia formosa	65.83	4.00e-110	390.00
IUUC-Pab-097823	Pongo abelii	95.57	1.00e-96	345.00
IUUC-Pca-101068	Procavia capensis	96.71	4.00e-159	553.00
IUUC-Rno-105288	Rattus norvegicus	96.38	1.00e-158	551.00
IUUC-Sar-113453	Sorex araneus	82.57	2.00e-143	501.00
IUUC-Tgu-116926	Taeniopygia guttata	84.92	1.00e-146	511.00
IUUC-Tru-118656	Takifugu rubripes	64.94	1.00e-118	419.00
IUUC-Tni-120497	Tetraodon nigroviridis	68.17	5.00e-114	403.00
IUUC-Tbe-127436	Tupaia belangeri	92.43	7.00e-141	493.00
IUUC-Ttr-129109	Tursiops truncatus	96.41	9.00e-127	445.00
IUUC-Vpa-130527	Vicugna pacos	96.38	6.00e-157	546.00
IUUC-Xtr-131808	Xenopus tropicalis	82.62	3.00e-147	514.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence