iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089221

Ensembl Protein ID

ENSOARP00000013155.1

UniProt Accession

W5PRS6; W5PRS6_SHEEP

Genbank Protein ID

ENSOARP00000013155

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01017864

Gene Name

CRK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000012278.1	ENSOART00000013349.1	ENSOARP00000013155.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.70e-18	66.5	135	190

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            e+v++l+d++++++++L +kkGd++++   ++ +e W+++ ++ egkrG++P  +vek
   Q: 135  AEYVRALFDFNGNDEEDLPFKKGDILRI--RDKPEEQWWNA-EDSEGKRGMIPVPYVEK 190
           689*************************..6999******9.5**************98 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MAGNFDSEER SSWYGERLSR QEAVALLQGQ RHGVFLVRDS STSPGDYVLS VSENPRVSHY 60
YIINSSGPRP PVPPSPAQPP PGVSPSRLRI GDQEFDSLPA LLEFYKIHYL DTTTLIEPVS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGGCA ACTTCGACTC GGAGGAGCGG AGTAGCTGGT ACGGGGAGCG GCTGAGTCGG 60
CAGGAGGCGG TGGCGCTGTT GCAGGGCCAG CGGCACGGGG TGTTCCTGGT GCGGGACTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0070062--C:extracellular exosome
GO:0048013--P:ephrin receptor signaling pathway
GO:0009967--P:positive regulation of signal transduction
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:0032956--P:regulation of actin cytoskeleton organization
GO:0043087--P:regulation of GTPase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001192	Ailuropoda melanoleuca	98.00	8.00e-156	542.00
IUUC-Apl-003225	Anas platyrhynchos	91.56	1.00e-122	431.00
IUUC-Aca-004818	Anolis carolinensis	78.35	5.00e-93	333.00
IUUC-Ame-011721	Astyanax mexicanus	67.51	9.00e-115	406.00
IUUC-Bta-012320	Bos taurus	98.36	3.00e-159	553.00
IUUC-Cel-018307	Caenorhabditis elegans	30.56	4.00e-25	108.00
IUUC-Cja-019935	Callithrix jacchus	94.75	4.00e-163	566.00
IUUC-Cfa-021221	Canis familiaris	98.03	5.00e-159	553.00
IUUC-Cpo-021592	Cavia porcellus	85.47	9.00e-135	472.00
IUUC-Csa-024128	Chlorocebus sabaeus	97.55	2.00e-96	344.00
IUUC-Cho-024775	Choloepus hoffmanni	96.39	2.00e-157	548.00
IUUC-Cin-025128	Ciona intestinalis	45.57	6.00e-70	257.00
IUUC-Csv-026340	Ciona savignyi	44.41	2.00e-63	235.00
IUUC-Dre-027390	Danio rerio	67.80	9.00e-116	409.00
IUUC-Dno-029847	Dasypus novemcinctus	98.36	3.00e-159	553.00
IUUC-Dor-030360	Dipodomys ordii	88.52	1.00e-152	531.00
IUUC-Dme-031600	Drosophila melanogaster	44.75	5.00e-63	234.00
IUUC-Ete-032604	Echinops telfairi	96.41	6.00e-126	442.00
IUUC-Eca-033233	Equus caballus	96.72	8.00e-159	552.00
IUUC-Eeu-034642	Erinaceus europaeus	97.31	5.00e-128	449.00
IUUC-Fca-035955	Felis catus	99.11	3.00e-131	460.00
IUUC-Fal-037152	Ficedula albicollis	84.70	4.00e-140	490.00
IUUC-Gmo-038849	Gadus morhua	66.25	2.00e-113	402.00
IUUC-Gga-040861	Gallus gallus	81.64	5.00e-147	513.00
IUUC-Gac-041627	Gasterosteus aculeatus	65.53	2.00e-116	411.00
IUUC-Ggo-045475	Gorilla gorilla	98.36	3.00e-159	553.00
IUUC-Hsa-046008	Homo sapiens	98.36	3.00e-159	553.00
IUUC-Itr-048906	Ictidomys tridecemlineatus	97.71	2.00e-129	454.00
IUUC-Lch-050509	Latimeria chalumnae	79.68	9.00e-144	502.00
IUUC-Loc-052229	Lepisosteus oculatus	71.69	6.00e-105	373.00
IUUC-Laf-053896	Loxodonta africana	93.51	3.00e-162	564.00
IUUC-Mcc-055280	Macaca mulatta	98.36	3.00e-159	553.00
IUUC-Meu-056783	Macropus eugenii	96.41	1.00e-126	444.00
IUUC-Mga-059345	Meleagris gallopavo	91.93	1.00e-123	435.00
IUUC-Mdo-062691	Monodelphis domestica	87.01	7.00e-151	526.00
IUUC-Mmu-063691	Mus musculus	98.03	6.00e-159	553.00
IUUC-Mpu-065737	Mustela putorius furo	98.03	3.00e-159	553.00
IUUC-Mlu-067005	Myotis lucifugus	95.08	2.00e-154	537.00
IUUC-Nle-070154	Nomascus leucogenys	99.11	4.00e-131	459.00
IUUC-Opr-071114	Ochotona princeps	96.72	8.00e-162	562.00
IUUC-Ont-071696	Oreochromis niloticus	68.57	3.00e-111	394.00
IUUC-Oan-072967	Ornithorhynchus anatinus	91.57	4.00e-128	450.00
IUUC-Ocu-074025	Oryctolagus cuniculus	96.57	4.00e-95	340.00
IUUC-Olo-080293	Oryza longistaminata	40.00	2.00e+00	25.80
IUUC-Oga-088266	Otolemur garnettii	97.05	3.00e-158	550.00
IUUC-Ptr-091463	Pan troglodytes	94.10	1.00e-147	515.00
IUUC-Pan-092242	Papio anubis	98.03	3.00e-159	553.00
IUUC-Psi-093287	Pelodiscus sinensis	94.20	1.00e-126	444.00
IUUC-Pma-094340	Petromyzon marinus	57.55	2.00e-96	345.00
IUUC-Pfo-097378	Poecilia formosa	65.31	3.00e-106	377.00
IUUC-Pab-097823	Pongo abelii	97.55	2.00e-96	344.00
IUUC-Pca-101068	Procavia capensis	98.36	3.00e-159	553.00
IUUC-Ptt-103815	Puccinia triticina	37.93	4.00e-09	55.50
IUUC-Rno-105288	Rattus norvegicus	98.03	1.00e-158	551.00
IUUC-Sar-113453	Sorex araneus	83.28	9.00e-143	499.00
IUUC-Tgu-116926	Taeniopygia guttata	82.30	4.00e-146	510.00
IUUC-Tru-118656	Takifugu rubripes	65.65	7.00e-117	413.00
IUUC-Tni-120497	Tetraodon nigroviridis	68.49	5.00e-112	397.00
IUUC-Tbe-127436	Tupaia belangeri	93.44	3.00e-140	491.00
IUUC-Ttr-129109	Tursiops truncatus	99.55	3.00e-130	457.00
IUUC-Vpa-130527	Vicugna pacos	98.03	3.00e-157	547.00
IUUC-Xtr-131808	Xenopus tropicalis	83.28	1.00e-146	512.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence