iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003900

Ensembl Protein ID

ENSAPLP00000010681.1

UniProt Accession

U3ITV8; U3ITV8_ANAPL

Genbank Protein ID

ENSAPLP00000010681

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01120397

Gene Name

IFIH1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000010913.1	ENSAPLT00000011398.1	ENSAPLP00000010681.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	1.30e-17	63.9	112	184

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 2    deeyrlllstlqdrvrklLdvtdvldkylse.flleeekelilaaaetkgnmqaaelLLktLvqkegWfrefl 73
           ++  ++l+++l +++++++  ++v   +l+   + ee  e i a  +t gn ++a++LL+++vqk+ Wf+ fl
   Q: 112  HDLCVQLVQLLHATLVDKMRARQVAEMCLQMnIFQEEDLERISAVTQTRGNRDGARELLSRIVQKKDWFSPFL 184
           57889***********************9861555566688889999**********************9885 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

MSTECRDECF LYMISCFRPR LKQYIRVMPV LDRLPSLSRE DREKVRVAAE QRGDVEGAEE 60
LLRAVERGPR DPGWFPEFVQ ALEYGGCDLX CDLAARYLNS SQLPSPTEEA DHDLCVQLVQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGACGG AGTGCCGAGA CGAGTGCTTC CTCTACATGA TCTCCTGCTT CAGGCCGCGG 60
CTGAAGCAAT ACATCCGGGT GATGCCGGTG CTGGACAGGC TGCCCTCGCT GAGCCGGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0043021--F:ribonucleoprotein complex binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0039530--P:MDA-5 signaling pathway
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001336	Ailuropoda melanoleuca	59.86	0.00e+00	1123.00
IUUC-Aca-005329	Anolis carolinensis	62.88	0.00e+00	1111.00
IUUC-Ame-011305	Astyanax mexicanus	57.63	0.00e+00	788.00
IUUC-Bta-012361	Bos taurus	59.50	0.00e+00	1083.00
IUUC-Cja-018760	Callithrix jacchus	60.56	0.00e+00	1082.00
IUUC-Cfa-020321	Canis familiaris	58.96	0.00e+00	1105.00
IUUC-Cpo-022450	Cavia porcellus	59.71	0.00e+00	1121.00
IUUC-Cre-022916	Chlamydomonas reinhardtii	33.33	4.00e-11	63.90
IUUC-Csa-024194	Chlorocebus sabaeus	61.54	0.00e+00	1087.00
IUUC-Cho-024364	Choloepus hoffmanni	54.91	0.00e+00	740.00
IUUC-Cin-025792	Ciona intestinalis	31.29	8.00e-78	284.00
IUUC-Dre-028305	Danio rerio	55.45	0.00e+00	711.00
IUUC-Dno-029831	Dasypus novemcinctus	60.54	0.00e+00	1127.00
IUUC-Dor-030410	Dipodomys ordii	67.31	0.00e+00	808.00
IUUC-Ete-032950	Echinops telfairi	62.04	9.00e-147	514.00
IUUC-Eca-034279	Equus caballus	60.90	0.00e+00	1121.00
IUUC-Eeu-034678	Erinaceus europaeus	57.07	0.00e+00	1090.00
IUUC-Fca-035618	Felis catus	65.96	0.00e+00	719.00
IUUC-Fal-037106	Ficedula albicollis	78.40	0.00e+00	1491.00
IUUC-Fso-038398	Fusarium solani	26.74	3.00e-29	124.00
IUUC-Gmo-038598	Gadus morhua	51.78	0.00e+00	681.00
IUUC-Gga-040467	Gallus gallus	82.48	0.00e+00	1660.00
IUUC-Gac-042316	Gasterosteus aculeatus	48.02	0.00e+00	839.00
IUUC-Ggo-045461	Gorilla gorilla	61.34	0.00e+00	1080.00
IUUC-Hsa-045771	Homo sapiens	61.15	0.00e+00	1076.00
IUUC-Itr-048762	Ictidomys tridecemlineatus	60.86	0.00e+00	1114.00
IUUC-Lch-049913	Latimeria chalumnae	68.01	0.00e+00	952.00
IUUC-Loc-052768	Lepisosteus oculatus	53.22	0.00e+00	1025.00
IUUC-Laf-053933	Loxodonta africana	60.45	0.00e+00	1087.00
IUUC-Mcc-054695	Macaca mulatta	61.54	0.00e+00	1090.00
IUUC-Meu-056829	Macropus eugenii	62.24	0.00e+00	933.00
IUUC-Mga-059205	Meleagris gallopavo	81.43	0.00e+00	1644.00
IUUC-Mvi-060497	Microbotryum violaceum	34.07	9.00e-16	79.70
IUUC-Mmr-060703	Microcebus murinus	60.02	0.00e+00	1084.00
IUUC-Mdo-063079	Monodelphis domestica	60.91	0.00e+00	1187.00
IUUC-Mmu-064066	Mus musculus	60.44	0.00e+00	1160.00
IUUC-Mpu-066261	Mustela putorius furo	59.73	0.00e+00	1115.00
IUUC-Mlu-068196	Myotis lucifugus	59.18	0.00e+00	1078.00
IUUC-Nfi-068405	Neosartorya fischeri	27.03	2.00e-26	115.00
IUUC-Nle-069479	Nomascus leucogenys	61.05	0.00e+00	1080.00
IUUC-Opr-070717	Ochotona princeps	53.92	0.00e+00	763.00
IUUC-Ont-071702	Oreochromis niloticus	48.66	0.00e+00	887.00
IUUC-Oan-073639	Ornithorhynchus anatinus	60.15	0.00e+00	1030.00
IUUC-Ocu-074521	Oryctolagus cuniculus	60.35	0.00e+00	1113.00
IUUC-Ola-086351	Oryzias latipes	46.78	0.00e+00	802.00
IUUC-Oga-088539	Otolemur garnettii	59.54	0.00e+00	1090.00
IUUC-Oar-090186	Ovis aries	60.10	0.00e+00	1075.00
IUUC-Ptr-090575	Pan troglodytes	60.35	0.00e+00	1071.00
IUUC-Pan-092371	Papio anubis	61.73	0.00e+00	1090.00
IUUC-Psi-093072	Pelodiscus sinensis	73.68	0.00e+00	1491.00
IUUC-Pma-094345	Petromyzon marinus	45.09	2.00e-97	349.00
IUUC-Pfo-096401	Poecilia formosa	54.89	0.00e+00	703.00
IUUC-Pab-097623	Pongo abelii	60.66	0.00e+00	1071.00
IUUC-Pca-100993	Procavia capensis	54.94	0.00e+00	879.00
IUUC-Pva-102227	Pteropus vampyrus	56.43	0.00e+00	999.00
IUUC-Pgr-103529	Puccinia graminis	28.10	4.00e-30	127.00
IUUC-Rno-105198	Rattus norvegicus	59.65	0.00e+00	1123.00
IUUC-Sha-107622	Sarcophilus harrisii	60.42	0.00e+00	1172.00
IUUC-Sar-113625	Sorex araneus	67.28	8.00e-124	437.00
IUUC-Tgu-117486	Taeniopygia guttata	78.67	0.00e+00	1525.00
IUUC-Tru-118445	Takifugu rubripes	46.08	0.00e+00	822.00
IUUC-Tsy-119512	Tarsius syrichta	59.20	0.00e+00	1023.00
IUUC-Tni-120711	Tetraodon nigroviridis	45.60	0.00e+00	835.00
IUUC-Tbe-127644	Tupaia belangeri	54.00	0.00e+00	965.00
IUUC-Ttr-128989	Tursiops truncatus	55.50	0.00e+00	1019.00
IUUC-Vpa-130587	Vicugna pacos	58.28	0.00e+00	904.00
IUUC-Xtr-132127	Xenopus tropicalis	55.28	0.00e+00	1058.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence