iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106475

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01070213

Gene Name

CDC34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000010655.1	ENSSHAT00000012544.1	ENSSHAP00000012442.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.30e-31	108.6	2	105

Active Site

Position(s)	Description	Evidence
45	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 42   YeggvF...kleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk...........eeekWspalsvesvllsiqsllaepnpes 116
           Ye+g +   +++++fp dYP++PP ++fltk++hPn+ye+G+vC+sil+           ++e+W+p+++v+++lls++sll+epn+ s
   Q: 2    YEKGSYfppQARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHppvddpqsgelPSERWNPTQNVRTILLSVISLLNEPNTFS 90
           888877555699************************************999999999*9****************************** PP
   S: 117  plneeaaellkknre 131
           p+n++a+ +++k++ 
   Q: 91   PANVDASVMYRKWKD 105
           **********99886 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

YYEKGSYFPP QARLKFPIDY PYSPPAFRFL TKMWHPNIYE TGDVCISILH PPVDDPQSGE 60
LPSERWNPTQ NVRTILLSVI SLLNEPNTFS PANVDASVMY RKWKDSKGKD REYTDIIRKQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATTATGAAA AGGGCAGGGA AGAGTATAGG AAGAATTCTC TACTTATCTT TAGGGACAAA 60
CAGGTCTCTC CTCTTCCATG ACAGTAATAG CTTTCATGTC AGAAGGTAGA AAGATGGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005829--C:cytosol
GO:0016607--C:nuclear speck
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0035458--P:cellular response to interferon-beta
GO:0043951--P:negative regulation of cAMP-mediated signaling
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Fca-035832	Felis catus	99.32	9.00e-85	305.00
IUUC-Fal-036936	Ficedula albicollis	96.62	7.00e-83	298.00
IUUC-Itr-047928	Ictidomys tridecemlineatus	97.97	3.00e-84	303.00
IUUC-Meu-056360	Macropus eugenii	99.44	1.00e-88	318.00
IUUC-Mlu-067860	Myotis lucifugus	99.32	4.00e-85	306.00
IUUC-Oar-090180	Ovis aries	98.65	1.00e-84	304.00
IUUC-Psi-093039	Pelodiscus sinensis	94.51	2.00e-89	320.00
IUUC-Pca-100169	Procavia capensis	86.43	1.00e-65	241.00
IUUC-Pva-102875	Pteropus vampyrus	96.36	2.00e-84	303.00
IUUC-Ssc-115699	Sus scrofa	85.16	5.00e-84	303.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence