iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-120850

UUCD1 version

UUC-TeN-00898

Ensembl Protein ID

ENSTNIP00000018976.1

UniProt Accession

H3DEN3; H3DEN3_TETNG

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000015891.1	ENSTNIT00000019204.1	ENSTNIP00000018976.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	5.00e-114	381.4	36	399

Active Site

Position(s)	Description	Evidence
367	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrl 87
           ++k +++v+fv+     E+g+d++Gv++efl++++k+++np l+lf+++++++  l+p+p+s++++ +hl+lFef+G++lgka+++g +
   Q: 36   SIKGVIRVKFVNdlgvdEAGIDQDGVFKEFLEEIIKKVFNPALNLFKTTSGNE-RLYPSPTSYIHE-NHLQLFEFVGKMLGKAVYEGIV 122
           67899*****************************************9888655.569*******76.********************** PP
   S: 88   ldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNke 171
           +d+p++++f++++lg+       s+++l+++d+e+yk+l++ik++ + d+ +lgl+l++  +e+++g+  ++eL+pgG+++pVtneNk 
   Q: 123  VDVPFASFFLSQVLGHhhstfYSSIDELPSLDSEFYKNLTSIKRY-DGDVGDLGLTLSY--DEDVMGQLVCHELIPGGKTMPVTNENKI 208
           ****************777777999********************.7899998777776..5999************************ PP
   S: 172  eYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevl.eefss 258
           +Y++l++++r++++ikeq++af +Gf+++i++e+l +F++ e++ l++G+ +eid++dlkk+t y gg+++++++i+w+w++l ++f++
   Q: 209  SYIHLMAHFRMHTQIKEQTAAFIRGFRSIINPEWLHMFSTPEVQRLVSGDnAEIDLDDLKKHTVYYGGFHSSHRVIIWLWDILsSDFTA 297
           **************************************************9********************************999*** PP
   S: 259  eerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekL 323
           eer++fL+FvT++sr Pl Gfa+lk                        + +f+irk++   rlP+s+TCfn+LkLP+Ys+k+il++kL
   Q: 298  EERAMFLKFVTSCSRPPLLGFAYLKppfsircvevsddqdtgdtlgsvlRGFFTIRKKEPGGRLPTSSTCFNLLKLPNYSKKSILRDKL 386
           *********************************************************9999**************************** PP
   S: 324  lyAieetkgFels 336
           +yAi++++gFels
   Q: 387  RYAISMNTGFELS 399
           **********985 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

LIETSSASPH VTHITIRRSR MLEDGYDQLR RLPANSIKGV IRVKFVNDLG VDEAGIDQDG 60
VFKEFLEEII KKVFNPALNL FKTTSGNERL YPSPTSYIHE NHLQLFEFVG KMLGKAVYEG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGATCGAGA CAAGCTCCGC TTCGCCACAC GTCACCCACA TTACCATCCG CCGCTCACGG 60
ATGTTAGAAG TATGGACTCT ACCTATCAGA CATGATATAC GGTTTTTTAA AACTCCCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002107	Ailuropoda melanoleuca	91.48	0.00e+00	774.00
IUUC-Apl-003328	Anas platyrhynchos	91.73	0.00e+00	777.00
IUUC-Bta-013547	Bos taurus	91.48	0.00e+00	778.00
IUUC-Cel-018447	Caenorhabditis elegans	60.65	7.00e-139	488.00
IUUC-Cja-019855	Callithrix jacchus	91.48	0.00e+00	776.00
IUUC-Cfa-020066	Canis familiaris	90.72	0.00e+00	748.00
IUUC-Cpo-021504	Cavia porcellus	91.73	0.00e+00	777.00
IUUC-Csa-023579	Chlorocebus sabaeus	91.23	0.00e+00	774.00
IUUC-Cho-024430	Choloepus hoffmanni	69.66	2.00e-103	370.00
IUUC-Cin-025750	Ciona intestinalis	64.56	8.00e-156	544.00
IUUC-Csv-026016	Ciona savignyi	66.17	4.00e-164	572.00
IUUC-Dre-028271	Danio rerio	97.49	0.00e+00	815.00
IUUC-Dno-029054	Dasypus novemcinctus	91.23	0.00e+00	774.00
IUUC-Dor-030938	Dipodomys ordii	91.98	0.00e+00	776.00
IUUC-Dme-031602	Drosophila melanogaster	70.18	2.00e-171	596.00
IUUC-Ete-033041	Echinops telfairi	89.14	8.00e-144	504.00
IUUC-Eca-034411	Equus caballus	90.98	0.00e+00	771.00
IUUC-Eeu-035201	Erinaceus europaeus	83.71	6.00e-159	555.00
IUUC-Fca-036594	Felis catus	90.23	0.00e+00	767.00
IUUC-Fal-037317	Ficedula albicollis	91.73	0.00e+00	778.00
IUUC-Gmo-039412	Gadus morhua	97.49	0.00e+00	817.00
IUUC-Gga-040149	Gallus gallus	91.73	0.00e+00	777.00
IUUC-Gac-042088	Gasterosteus aculeatus	98.25	0.00e+00	824.00
IUUC-Ggo-045279	Gorilla gorilla	91.48	0.00e+00	776.00
IUUC-Hsa-045660	Homo sapiens	91.48	0.00e+00	774.00
IUUC-Itr-048372	Ictidomys tridecemlineatus	91.73	0.00e+00	774.00
IUUC-Kpa-049307	Komagataella pastoris	35.40	2.00e-63	237.00
IUUC-Lch-050664	Latimeria chalumnae	93.98	0.00e+00	800.00
IUUC-Loc-052791	Lepisosteus oculatus	97.00	0.00e+00	810.00
IUUC-Laf-053902	Loxodonta africana	91.23	0.00e+00	775.00
IUUC-Mcc-054730	Macaca mulatta	91.23	0.00e+00	774.00
IUUC-Meu-056527	Macropus eugenii	78.95	0.00e+00	644.00
IUUC-Mga-059260	Meleagris gallopavo	91.73	0.00e+00	778.00
IUUC-Mmr-060804	Microcebus murinus	90.98	0.00e+00	773.00
IUUC-Mdo-062575	Monodelphis domestica	91.48	0.00e+00	771.00
IUUC-Mmu-063636	Mus musculus	91.23	0.00e+00	775.00
IUUC-Mpu-066677	Mustela putorius furo	90.77	0.00e+00	651.00
IUUC-Mlu-067952	Myotis lucifugus	91.48	0.00e+00	773.00
IUUC-Nle-069153	Nomascus leucogenys	91.48	0.00e+00	774.00
IUUC-Opr-070554	Ochotona princeps	90.73	0.00e+00	769.00
IUUC-Ont-071372	Oreochromis niloticus	98.75	0.00e+00	826.00
IUUC-Oan-073426	Ornithorhynchus anatinus	87.38	8.00e-110	389.00
IUUC-Ocu-074183	Oryctolagus cuniculus	90.98	0.00e+00	772.00
IUUC-Ome-081741	Oryza meridionalis	42.71	2.00e-86	313.00
IUUC-Ola-087337	Oryzias latipes	97.99	0.00e+00	818.00
IUUC-Oga-088342	Otolemur garnettii	90.50	0.00e+00	767.00
IUUC-Oar-090234	Ovis aries	90.72	0.00e+00	751.00
IUUC-Ptr-091661	Pan troglodytes	91.23	0.00e+00	774.00
IUUC-Pan-092728	Papio anubis	90.75	0.00e+00	768.00
IUUC-Psi-093251	Pelodiscus sinensis	90.48	0.00e+00	648.00
IUUC-Pma-094195	Petromyzon marinus	81.20	0.00e+00	695.00
IUUC-Pfo-097472	Poecilia formosa	99.00	0.00e+00	827.00
IUUC-Pab-098570	Pongo abelii	91.48	0.00e+00	775.00
IUUC-Pca-100110	Procavia capensis	87.22	0.00e+00	734.00
IUUC-Pva-102887	Pteropus vampyrus	91.23	0.00e+00	773.00
IUUC-Rno-106028	Rattus norvegicus	83.50	0.00e+00	683.00
IUUC-Sha-107331	Sarcophilus harrisii	91.23	0.00e+00	772.00
IUUC-Sar-113287	Sorex araneus	76.39	4.00e-137	482.00
IUUC-Ssc-116103	Sus scrofa	91.48	0.00e+00	773.00
IUUC-Tgu-117275	Taeniopygia guttata	91.73	0.00e+00	776.00
IUUC-Tru-118681	Takifugu rubripes	99.75	0.00e+00	831.00
IUUC-Tsy-118985	Tarsius syrichta	83.96	8.00e-107	381.00
IUUC-Tbe-127461	Tupaia belangeri	79.45	0.00e+00	636.00
IUUC-Ttr-129269	Tursiops truncatus	91.48	0.00e+00	773.00
IUUC-Vpa-130523	Vicugna pacos	89.93	3.00e-81	296.00
IUUC-Xtr-132146	Xenopus tropicalis	90.23	0.00e+00	771.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence