iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066013

Ensembl Protein ID

ENSMPUP00000003291.1

UniProt Accession

M3XW41; M3XW41_MUSPF

Genbank Protein ID

ENSMPUP00000003291

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01037849

Gene Name

OTUB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000003323.1	ENSMPUT00000003356.1	ENSMPUP00000003291.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	1.50e-48	164.7	40	229

Active Site

Position(s)	Description	Evidence
47	N/A	{ECO:0000256\|PIRSR:PIRSR013503-1}
50	Nucleophile	{ECO:0000256\|PIRSR:PIRSR013503-1}
223		{ECO:0000256\|PIRSR:PIRSR013503-1}

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqs..........................................................llgvfdddslsd 32
           +i+ktkgDGnC++rA+++s                                                          ll+vf+d+s+sd
   Q: 40   AIRKTKGDGNCFYRALGYSylesllgksrevlkfkervlqtpndllaagfeehkfrnffnafysvvelvekdgsvssLLKVFNDQSASD 128
           79*************************************************************************************** PP
   S: 33   alveaLreltseylqkesdffsefieekedekefcqklvepeak.geeihifaLaqiLsrpiivvdvdsleskvggillpllfpeeklk 120
           ++v++Lr+lts++++++++ff++fi+e++d+k+fc+++vep+a  +++i+i+aL+q+L+++++v++vd++++    +l++++fpe++ +
   Q: 129  QIVQFLRLLTSAFIKNRAEFFRHFIDEEMDIKDFCTHEVEPMAMeCDHIQITALSQALNIALQVEYVDEMDT----ALNHHVFPEAA-T 212
           **********************************************************************95....***********.* PP
   S: 121  kpivLlYrsgHYdaLva 137
           ++++LlY+++HY++L+a
   Q: 213  PSVYLLYKTSHYNILYA 229
           ***************97 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

SETSFNLISE KCDILSILRD HPENRIYQRK IQELSKRFTA IRKTKGDGNC FYRALGYSYL 60
ESLLGKSREV LKFKERVLQT PNDLLAAGFE EHKFRNFFNA FYSVVELVEK DGSVSSLLKV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTCAATCGC GGGGCGTGTG TCTTGCTGGG ACACAGTGGA GGTCTACCCT GTGGTTTGCG 60
GAGTGGTCGG GTGTATTCTC CGCTCGCCCC CACGCCCTCG AGGCCCCCGC CGCCCGACCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR030299--OTUB2
IPR016615--Otubain
IPR019400--Peptidase_C65_otubain

PROSITE

PS50802--OTU

Pfam

PF10275--Peptidase_C65

Gene Ontology

GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002059	Ailuropoda melanoleuca	99.14	9.00e-137	478.00
IUUC-Bta-012766	Bos taurus	96.55	5.00e-133	466.00
IUUC-Cja-019480	Callithrix jacchus	95.24	1.00e-130	458.00
IUUC-Cfa-021106	Canis familiaris	98.71	1.00e-136	478.00
IUUC-Cpo-022187	Cavia porcellus	95.26	8.00e-132	462.00
IUUC-Csa-023493	Chlorocebus sabaeus	96.12	2.00e-132	464.00
IUUC-Cho-024411	Choloepus hoffmanni	77.07	4.00e-86	310.00
IUUC-Dno-029346	Dasypus novemcinctus	97.00	1.00e-134	471.00
IUUC-Dor-031012	Dipodomys ordii	97.84	1.00e-134	471.00
IUUC-Ete-032266	Echinops telfairi	88.41	1.00e-121	428.00
IUUC-Eca-033356	Equus caballus	97.42	1.00e-134	472.00
IUUC-Eeu-034775	Erinaceus europaeus	95.71	2.00e-133	467.00
IUUC-Fca-035363	Felis catus	95.69	2.00e-132	464.00
IUUC-Ggo-045023	Gorilla gorilla	95.69	7.00e-132	462.00
IUUC-Hsa-046984	Homo sapiens	96.12	2.00e-132	464.00
IUUC-Itr-048012	Ictidomys tridecemlineatus	96.55	1.00e-133	468.00
IUUC-Lch-050514	Latimeria chalumnae	60.44	9.00e-83	299.00
IUUC-Loc-052003	Lepisosteus oculatus	50.45	2.00e-64	238.00
IUUC-Laf-054382	Loxodonta africana	96.14	6.00e-134	469.00
IUUC-Mcc-055516	Macaca mulatta	96.12	1.00e-132	464.00
IUUC-Meu-056038	Macropus eugenii	87.83	3.00e-99	353.00
IUUC-Mmr-060918	Microcebus murinus	97.84	7.00e-135	472.00
IUUC-Mdo-062638	Monodelphis domestica	90.09	7.00e-125	439.00
IUUC-Mmu-063973	Mus musculus	95.69	1.00e-132	465.00
IUUC-Mlu-067509	Myotis lucifugus	94.85	3.00e-130	457.00
IUUC-Nle-069673	Nomascus leucogenys	96.12	2.00e-132	464.00
IUUC-Opr-070761	Ochotona princeps	87.27	2.00e-81	293.00
IUUC-Oan-072922	Ornithorhynchus anatinus	82.10	7.00e-113	399.00
IUUC-Ocu-074643	Oryctolagus cuniculus	95.26	4.00e-132	463.00
IUUC-Oni-082026	Oryza nivara	28.32	1.00e-15	77.40
IUUC-Oru-084761	Oryza rufipogon	28.32	1.00e-15	77.40
IUUC-Ola-086603	Oryzias latipes	44.91	1.00e-51	195.00
IUUC-Oga-088936	Otolemur garnettii	96.12	1.00e-132	465.00
IUUC-Oar-089460	Ovis aries	96.98	4.00e-133	466.00
IUUC-Ptr-090805	Pan troglodytes	95.69	4.00e-132	463.00
IUUC-Pan-091969	Papio anubis	96.12	2.00e-132	464.00
IUUC-Pab-098476	Pongo abelii	95.69	7.00e-132	462.00
IUUC-Pca-100252	Procavia capensis	93.00	2.00e-53	202.00
IUUC-Pva-102204	Pteropus vampyrus	95.69	2.00e-133	467.00
IUUC-Pgr-103552	Puccinia graminis	75.00	2.50e-02	31.60
IUUC-Rno-105062	Rattus norvegicus	95.69	8.00e-133	465.00
IUUC-Sha-106968	Sarcophilus harrisii	89.96	3.00e-123	434.00
IUUC-Sar-113295	Sorex araneus	97.00	7.00e-133	465.00
IUUC-Ssc-115288	Sus scrofa	96.14	9.00e-134	468.00
IUUC-Tni-120440	Tetraodon nigroviridis	38.96	1.00e-42	166.00
IUUC-Tbe-127717	Tupaia belangeri	94.59	1.00e-78	284.00
IUUC-Ttr-128221	Tursiops truncatus	77.25	2.00e-101	361.00
IUUC-Uma-129443	Ustilago maydis	33.17	6.00e-24	104.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence