iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ola-087000

Ensembl Protein ID

ENSORLP00000021875.1

UniProt Accession

H2MSY2; H2MSY2_ORYLA

Genbank Protein ID

ENSORLP00000021875

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

BAAF04013853

Gene Name

lck

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000017495.1	ENSORLT00000021876.1	ENSORLP00000021875.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-12	48.0	63	114

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            + y+ye+++d++L ++kGd+++++  ++ d +W  +++ ++g++G +P nF++
   Q: 63   LAVYSYEPKHDGDLGFEKGDKLKIL--NKDDPEWYLAESLTTGQQGYIPFNFIA 114
           689**********************..8899*********************96 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

MGCACSTDSE EWLENLDDIC EHCNCPIPPQ SSKGKLSIYT DQLIQHPSSH SPPLSPLPDN 60
IALAVYSYEP KHDGDLGFEK GDKLKILNKD DPEWYLAESL TTGQQGYIPF NFIAMTTMET 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGATGTG CTTGCAGTAC AGATTCGGAA GAATGGTTGG AGAACCTGGA TGACATTTGC 60
GAACACTGCA ACTGTCCAAT ACCTCCCCAG TCAAGCAACA CAGTGAGTGA ACGTCTGTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001315	Ailuropoda melanoleuca	64.87	0.00e+00	711.00
IUUC-Apl-004134	Anas platyrhynchos	69.43	0.00e+00	633.00
IUUC-Ame-010831	Astyanax mexicanus	74.61	0.00e+00	679.00
IUUC-Bta-013264	Bos taurus	68.11	0.00e+00	728.00
IUUC-Cfa-021161	Canis familiaris	64.87	0.00e+00	712.00
IUUC-Cpo-022492	Cavia porcellus	68.57	0.00e+00	733.00
IUUC-Dre-028005	Danio rerio	72.46	0.00e+00	766.00
IUUC-Dno-029365	Dasypus novemcinctus	65.55	0.00e+00	682.00
IUUC-Dor-030892	Dipodomys ordii	68.08	0.00e+00	686.00
IUUC-Eca-033325	Equus caballus	67.39	0.00e+00	703.00
IUUC-Eeu-035004	Erinaceus europaeus	60.72	2.00e-156	545.00
IUUC-Fca-035908	Felis catus	68.50	0.00e+00	727.00
IUUC-Gmo-038984	Gadus morhua	74.16	0.00e+00	781.00
IUUC-Gga-040997	Gallus gallus	69.09	0.00e+00	743.00
IUUC-Gac-041854	Gasterosteus aculeatus	83.53	0.00e+00	872.00
IUUC-Ggo-045238	Gorilla gorilla	65.24	0.00e+00	715.00
IUUC-Hsa-047039	Homo sapiens	69.09	0.00e+00	730.00
IUUC-Itr-048479	Ictidomys tridecemlineatus	69.55	0.00e+00	734.00
IUUC-Lch-049568	Latimeria chalumnae	70.45	0.00e+00	750.00
IUUC-Loc-052222	Lepisosteus oculatus	70.67	0.00e+00	698.00
IUUC-Laf-054499	Loxodonta africana	64.68	0.00e+00	711.00
IUUC-Meu-056879	Macropus eugenii	67.64	0.00e+00	711.00
IUUC-Mga-059971	Meleagris gallopavo	68.05	0.00e+00	729.00
IUUC-Mmr-060740	Microcebus murinus	68.70	0.00e+00	730.00
IUUC-Mdo-062192	Monodelphis domestica	68.50	0.00e+00	729.00
IUUC-Mmu-064241	Mus musculus	68.50	0.00e+00	729.00
IUUC-Mpu-066595	Mustela putorius furo	69.29	0.00e+00	732.00
IUUC-Mlu-067069	Myotis lucifugus	68.37	0.00e+00	726.00
IUUC-Opr-070472	Ochotona princeps	65.36	0.00e+00	707.00
IUUC-Ont-071711	Oreochromis niloticus	85.12	0.00e+00	864.00
IUUC-Ocu-074221	Oryctolagus cuniculus	68.37	0.00e+00	719.00
IUUC-Oga-088225	Otolemur garnettii	67.91	0.00e+00	719.00
IUUC-Oar-090244	Ovis aries	60.04	0.00e+00	672.00
IUUC-Pan-091804	Papio anubis	69.49	0.00e+00	733.00
IUUC-Pfo-096542	Poecilia formosa	84.06	0.00e+00	882.00
IUUC-Pab-098168	Pongo abelii	69.90	0.00e+00	707.00
IUUC-Rno-105542	Rattus norvegicus	68.50	0.00e+00	731.00
IUUC-Sha-107524	Sarcophilus harrisii	68.70	0.00e+00	730.00
IUUC-Sar-113235	Sorex araneus	64.48	9.00e-178	616.00
IUUC-Ssc-115624	Sus scrofa	68.11	0.00e+00	721.00
IUUC-Tru-118559	Takifugu rubripes	78.63	0.00e+00	836.00
IUUC-Tni-119928	Tetraodon nigroviridis	72.21	0.00e+00	738.00
IUUC-Ttr-129002	Tursiops truncatus	62.83	0.00e+00	677.00
IUUC-Xtr-132224	Xenopus tropicalis	67.13	0.00e+00	705.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence