iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-090751

Ensembl Protein ID

ENSPTRP00000000842.4

UniProt Accession

H2PYK3; H2PYK3_PANTR

Genbank Protein ID

ENSPTRP00000000842

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03010809

Gene Name

LCK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000000479.6	ENSPTRT00000000940.4	ENSPTRP00000000842.4

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/SH3	99.71	0.00e+00	731.00	IUUC-Hsa-047039

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pan troglodytes

Protein Sequence
(Fasta)

SGSFSLSVRD FDQNQGEVVK HYKIRNLDNG GFYISPRITF PGLHELVRHY TNASDGLCTR 60
LSRPCQTQKP QKPWWEDEWE VPRETLKLVE RLGAGQFGEV WMGYYNGHTK VAVKSLKQGS 120

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Nucleotide Sequence
(Fasta)

TCAGGATCGT TTTCACTGTC GGTCCGGGAC TTCGACCAGA ACCAGGGAGA GGTGGTGAAA 60
CATTACAAGA TCCGTAATCT GGACAACGGT GGCTTCTACA TCTCCCCTCG AATCACTTTT 120

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Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00219--TyrKc

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0001772--C:immunological synapse
GO:0045121--C:membrane raft
GO:0000242--C:pericentriolar material
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0004722--F:protein serine/threonine phosphatase activity
GO:0005102--F:receptor binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0050853--P:B cell receptor signaling pathway
GO:0016477--P:cell migration
GO:0006882--P:cellular zinc ion homeostasis
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:2001244--P:positive regulation of intrinsic apoptotic signaling pathway
GO:0050870--P:positive regulation of T cell activation
GO:0042981--P:regulation of apoptotic process
GO:0042127--P:regulation of cell proliferation
GO:0042493--P:response to drug
GO:0030217--P:T cell differentiation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001315	Ailuropoda melanoleuca	90.79	0.00e+00	706.00
IUUC-Bta-013264	Bos taurus	96.29	0.00e+00	708.00
IUUC-Cja-019574	Callithrix jacchus	98.30	0.00e+00	714.00
IUUC-Cfa-021161	Canis familiaris	90.53	0.00e+00	705.00
IUUC-Cpo-022492	Cavia porcellus	97.71	0.00e+00	715.00
IUUC-Dno-029365	Dasypus novemcinctus	93.43	0.00e+00	675.00
IUUC-Dor-030892	Dipodomys ordii	90.21	0.00e+00	702.00
IUUC-Eca-033325	Equus caballus	98.57	0.00e+00	723.00
IUUC-Fca-035908	Felis catus	98.29	0.00e+00	721.00
IUUC-Fal-036804	Ficedula albicollis	88.29	3.00e-162	564.00
IUUC-Gma-043628	Glycine max	31.84	1.00e-20	95.10
IUUC-Ggo-045238	Gorilla gorilla	91.84	0.00e+00	716.00
IUUC-Hsa-047039	Homo sapiens	99.71	0.00e+00	731.00
IUUC-Hvu-047815	Hordeum vulgare	28.86	4.00e-20	93.60
IUUC-Itr-048479	Ictidomys tridecemlineatus	98.00	0.00e+00	717.00
IUUC-Laf-054499	Loxodonta africana	90.77	0.00e+00	705.00
IUUC-Mcc-054872	Macaca mulatta	83.71	9.00e-168	583.00
IUUC-Meu-056879	Macropus eugenii	92.37	0.00e+00	681.00
IUUC-Mtr-058765	Medicago truncatula	34.15	4.00e-20	93.20
IUUC-Mmr-060740	Microcebus murinus	97.14	0.00e+00	711.00
IUUC-Mdo-062192	Monodelphis domestica	95.71	0.00e+00	706.00
IUUC-Mmu-064241	Mus musculus	97.14	0.00e+00	717.00
IUUC-Mpu-066595	Mustela putorius furo	98.29	0.00e+00	719.00
IUUC-Mlu-067069	Myotis lucifugus	97.43	0.00e+00	716.00
IUUC-Opr-070472	Ochotona princeps	91.47	0.00e+00	705.00
IUUC-Ocu-074221	Oryctolagus cuniculus	98.00	0.00e+00	722.00
IUUC-Oga-088225	Otolemur garnettii	97.43	0.00e+00	714.00
IUUC-Oar-090244	Ovis aries	97.14	0.00e+00	712.00
IUUC-Pan-091804	Papio anubis	98.57	0.00e+00	721.00
IUUC-Psi-093252	Pelodiscus sinensis	82.91	4.00e-174	604.00
IUUC-Pab-098168	Pongo abelii	99.14	0.00e+00	725.00
IUUC-Rno-105542	Rattus norvegicus	96.86	0.00e+00	716.00
IUUC-Sha-107524	Sarcophilus harrisii	94.00	0.00e+00	695.00
IUUC-Ssc-115624	Sus scrofa	96.57	0.00e+00	710.00
IUUC-Tca-121341	Theobroma cacao	32.70	6.00e-22	99.80

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence