iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003481

Ensembl Protein ID

ENSAPLP00000008640.1

UniProt Accession

U3IN17; U3IN17_ANAPL

Genbank Protein ID

ENSAPLP00000008640

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01128019

Gene Name

KLHL20

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000008931.1	ENSAPLT00000009322.1	ENSAPLP00000008640.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.70e-22	78.6	76	143
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.50e-11	43.3	175	206

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dv+lvvg +++ ah+++L+a+S++F+a+f++el es+ + +v+i+d++  +++ l++F Yt++++ +e
   Q: 76   CDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESR-QTEVVIRDIDERAMELLIDFAYTSQITVEE 143
           9*************************************.*************************98765 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclgi++fAd+++c++L   a++f++++F+
   Q: 175  PSNCLGIRAFADTHSCRELLRIADKFTQHNFQ 206
           89*****************************6 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

SEGFSSRCMD GKPMRRCTST RPGETGMDVT SRCTLGDPNK LPEGVPQPAR MPYISDKHPR 60
QTLEVINLLR KHRELCDVVL VVGAKKIYAH RVILSACSPY FRAMFTGELA ESRQTEVVIR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTGAAGGTT TCTCTTCACG GTGCATGGAC GGAAAGCCAA TGCGCAGGTA AGATGAAAAT 60
CAATTGTCCT TCTCTTACCC CAGTACAGTA TAATTTTGTT TGGTTTCAGA AGTGCCTACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0016605--C:PML body
GO:0005802--C:trans-Golgi network
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006895--P:Golgi to endosome transport
GO:0043066--P:negative regulation of apoptotic process
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:1990390--P:protein K33-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001974	Ailuropoda melanoleuca	98.52	0.00e+00	1249.00
IUUC-Aca-004877	Anolis carolinensis	99.34	0.00e+00	1257.00
IUUC-Aly-005957	Arabidopsis lyrata	36.30	3.00e-40	159.00
IUUC-Aor-010180	Aspergillus oryzae	24.65	9.00e-10	57.40
IUUC-Ame-011440	Astyanax mexicanus	98.98	0.00e+00	1222.00
IUUC-Bta-012603	Bos taurus	99.34	0.00e+00	1258.00
IUUC-Bol-016130	Brassica oleracea	27.14	7.00e-16	79.00
IUUC-Bra-016881	Brassica rapa	27.27	4.00e-17	83.20
IUUC-Cel-018464	Caenorhabditis elegans	59.51	0.00e+00	716.00
IUUC-Cja-019119	Callithrix jacchus	99.34	0.00e+00	1258.00
IUUC-Cfa-020169	Canis familiaris	99.34	0.00e+00	1258.00
IUUC-Cpo-021519	Cavia porcellus	98.86	0.00e+00	1263.00
IUUC-Csa-024173	Chlorocebus sabaeus	99.34	0.00e+00	1258.00
IUUC-Cho-024820	Choloepus hoffmanni	90.95	0.00e+00	788.00
IUUC-Cin-025270	Ciona intestinalis	75.68	0.00e+00	892.00
IUUC-Csv-026308	Ciona savignyi	75.60	0.00e+00	899.00
IUUC-Dre-027423	Danio rerio	99.15	0.00e+00	1222.00
IUUC-Dno-029350	Dasypus novemcinctus	98.86	0.00e+00	1264.00
IUUC-Dor-031011	Dipodomys ordii	98.94	5.00e-167	580.00
IUUC-Dme-032170	Drosophila melanogaster	80.77	0.00e+00	958.00
IUUC-Ete-033187	Echinops telfairi	98.84	0.00e+00	881.00
IUUC-Eca-033751	Equus caballus	98.86	0.00e+00	1265.00
IUUC-Eeu-034901	Erinaceus europaeus	99.01	0.00e+00	1255.00
IUUC-Fca-035752	Felis catus	98.36	0.00e+00	1118.00
IUUC-Fal-037630	Ficedula albicollis	99.84	0.00e+00	1259.00
IUUC-Gmo-039481	Gadus morhua	97.54	0.00e+00	1244.00
IUUC-Gga-040971	Gallus gallus	100.00	0.00e+00	1265.00
IUUC-Gac-042602	Gasterosteus aculeatus	97.87	0.00e+00	1248.00
IUUC-Ggo-044588	Gorilla gorilla	98.86	0.00e+00	1265.00
IUUC-Hsa-046641	Homo sapiens	99.34	0.00e+00	1258.00
IUUC-Itr-048394	Ictidomys tridecemlineatus	99.50	0.00e+00	1248.00
IUUC-Lch-049968	Latimeria chalumnae	99.51	0.00e+00	1261.00
IUUC-Loc-052720	Lepisosteus oculatus	98.36	0.00e+00	1254.00
IUUC-Lma-053201	Leptosphaeria maculans	27.21	2.00e-09	56.20
IUUC-Laf-054156	Loxodonta africana	98.86	0.00e+00	1265.00
IUUC-Mcc-054629	Macaca mulatta	99.34	0.00e+00	1258.00
IUUC-Meu-056605	Macropus eugenii	100.00	0.00e+00	648.00
IUUC-Mga-060014	Meleagris gallopavo	99.01	0.00e+00	1235.00
IUUC-Mmr-060814	Microcebus murinus	98.84	0.00e+00	1245.00
IUUC-Mdo-062242	Monodelphis domestica	100.00	0.00e+00	1264.00
IUUC-Mmu-064309	Mus musculus	99.50	0.00e+00	1248.00
IUUC-Mpu-066587	Mustela putorius furo	99.34	0.00e+00	1258.00
IUUC-Mlu-066958	Myotis lucifugus	96.22	0.00e+00	1203.00
IUUC-Nle-069059	Nomascus leucogenys	97.87	0.00e+00	1234.00
IUUC-Ont-072129	Oreochromis niloticus	97.87	0.00e+00	1245.00
IUUC-Oan-073073	Ornithorhynchus anatinus	99.34	0.00e+00	1250.00
IUUC-Ocu-073909	Oryctolagus cuniculus	98.36	0.00e+00	1245.00
IUUC-Obr-076181	Oryza brachyantha	32.53	2.00e-34	141.00
IUUC-Ola-086392	Oryzias latipes	97.22	0.00e+00	1236.00
IUUC-Olu-087696	Ostreococcus lucimarinus	36.44	6.00e-32	130.00
IUUC-Oga-088693	Otolemur garnettii	98.36	0.00e+00	1248.00
IUUC-Oar-089905	Ovis aries	98.70	0.00e+00	1264.00
IUUC-Ptr-091059	Pan troglodytes	99.34	0.00e+00	1258.00
IUUC-Pan-091833	Papio anubis	94.62	0.00e+00	788.00
IUUC-Psi-093499	Pelodiscus sinensis	100.00	0.00e+00	1257.00
IUUC-Pma-094404	Petromyzon marinus	80.17	0.00e+00	945.00
IUUC-Pfo-096891	Poecilia formosa	97.87	0.00e+00	1244.00
IUUC-Pab-097715	Pongo abelii	94.91	0.00e+00	1190.00
IUUC-Pva-102944	Pteropus vampyrus	83.42	0.00e+00	1026.00
IUUC-Rno-104878	Rattus norvegicus	99.34	0.00e+00	1258.00
IUUC-Sha-107444	Sarcophilus harrisii	100.00	0.00e+00	1265.00
IUUC-Ssc-115565	Sus scrofa	99.50	0.00e+00	1246.00
IUUC-Tgu-116902	Taeniopygia guttata	99.84	0.00e+00	1277.00
IUUC-Tru-118692	Takifugu rubripes	97.87	0.00e+00	1246.00
IUUC-Tsy-119031	Tarsius syrichta	91.79	0.00e+00	1137.00
IUUC-Tbe-127517	Tupaia belangeri	93.51	0.00e+00	1154.00
IUUC-Ttr-128366	Tursiops truncatus	99.34	0.00e+00	1258.00
IUUC-Vpa-130465	Vicugna pacos	99.01	0.00e+00	1254.00
IUUC-Vvi-131673	Vitis vinifera	34.33	1.00e-42	167.00
IUUC-Xtr-132243	Xenopus tropicalis	99.02	0.00e+00	1253.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence