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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-046337
UUCD1 version UUC-HoS-00737
Ensembl Protein ID ENSP00000323913.4
UniProt Accession Q9BYV6; B3KRC0; B3KRJ3; Q53XX3; Q8IUD9; Q8IUE4; Q96DV2; Q96DV3; Q9BYV5; TRI55_HUMAN
Genbank Protein ID CAC32839.1; CAC32840.1; CAC43019.1; CAC43020.1; CAC81835.1; CAD24432.1; BAG52332.1; BAG52405.1; EAW86894.1; EAW86895.1; AAH07750.2; AAP35876.1
Protein Name Tripartite motif-containing protein 55; Muscle-specific RING finger protein 2; RING finger protein 29
Genbank Nucleotide ID AJ291712; AJ291712; AJ243488; AJ243489; AJ277493; AJ431704; AK091310; AK091728; CH471068; CH471068; BC007750; BT007212
Gene Name TRIM55; MURF2; RNF29
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000147573.16 ENST00000315962.8 ENSP00000323913.4
ENSG00000147573.16 ENST00000353317.9 ENSP00000297348.8
ENSG00000147573.16 ENST00000276573.11 ENSP00000276573.7
ENSG00000147573.16 ENST00000350034.4 ENSP00000332302.4
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsiteCircNetmicroRNA
TRANSFACTargetScanRepTarmiRNAMap
SomamiRmiRcodeRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Disease-associated Variation
GWASdbOMIM
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTM
DNA Methylation
MethyCancerTCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 2.60e-08 35.9 26 82
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw...........pglknssskefrCPlCr 46
           C+iCle+f +++++lpC+H  +++C   +            g    s ++frCP Cr
   Q: 26   CPICLEMFTKPVVILPCQHNLCRKCASDIfqasnpylptrGGTTMASGGRFRCPSCR 82
           *************************744445557779999777778**********8 PP
   
Organism Homo sapiens
Functional Description
(View)

Functional Description


     May regulate gene expression and protein turnover in muscle cells.
 May regulate gene expression and protein turnover in muscle cells.
Protein Sequence
(Fasta)
MSASLNYKSF SKEQQTMDNL EKQLICPICL EMFTKPVVIL PCQHNLCRKC ASDIFQASNP 60
YLPTRGGTTM ASGGRFRCPS CRHEVVLDRH GVYGLQRNLL VENIIDIYKQ ESTRPEKKSD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046337|E3,RING|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTTGTTGTTG ACAACTGTCA GCTTCGACCT CCTTCTCCTC ACAACCCCGT CTAAATGGGG 60
TTTGTAATCC TCCTTCCCAC CCACTCTCTT CACTCCCTGG GGCAAGAATG TTGACTCCTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046337|E3,RING|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0479--Metal-binding
KW-0514--Muscle protein
KW-0539--Nucleus
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR017903--COS_domain
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS51262--COS
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX
SMART

SM00336--BBOX
SM00184--RING
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005874--C:microtubule
GO:0005634--C:nucleus
GO:0042802--F:identical protein binding
GO:0004871--F:signal transducer activity
GO:0008270--F:zinc ion binding
GO:0007165--P:signal transduction
KEGG hsa:84675
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002421 Ailuropoda melanoleuca 90.24 0.00e+00 881.00
IUUC-Apl-003341 Anas platyrhynchos 89.70 0.00e+00 632.00
IUUC-Aca-005384 Anolis carolinensis 67.01 7.00e-176 610.00
IUUC-Ame-010720 Astyanax mexicanus 71.52 3.00e-139 488.00
IUUC-Bta-013040 Bos taurus 85.53 0.00e+00 827.00
IUUC-Cja-019932 Callithrix jacchus 96.17 0.00e+00 900.00
IUUC-Cfa-020450 Canis familiaris 91.27 0.00e+00 902.00
IUUC-Cpo-021767 Cavia porcellus 87.41 0.00e+00 868.00
IUUC-Csa-023600 Chlorocebus sabaeus 97.09 0.00e+00 907.00
IUUC-Cho-024753 Choloepus hoffmanni 75.00 0.00e+00 696.00
IUUC-Dre-028701 Danio rerio 70.57 6.00e-137 480.00
IUUC-Dno-030008 Dasypus novemcinctus 83.27 0.00e+00 840.00
IUUC-Ete-032274 Echinops telfairi 80.84 0.00e+00 786.00
IUUC-Eca-034326 Equus caballus 89.27 0.00e+00 837.00
IUUC-Fca-035385 Felis catus 90.65 0.00e+00 822.00
IUUC-Fal-036679 Ficedula albicollis 89.21 4.00e-176 611.00
IUUC-Gmo-039021 Gadus morhua 64.87 1.00e-119 422.00
IUUC-Gga-040576 Gallus gallus 88.89 8.00e-174 603.00
IUUC-Gac-042165 Gasterosteus aculeatus 66.87 4.00e-133 467.00
IUUC-Ggo-044496 Gorilla gorilla 99.09 0.00e+00 912.00
IUUC-Lch-050504 Latimeria chalumnae 64.45 4.00e-180 624.00
IUUC-Loc-052717 Lepisosteus oculatus 54.29 1.00e-152 533.00
IUUC-Laf-053838 Loxodonta africana 80.62 0.00e+00 818.00
IUUC-Mcc-054690 Macaca mulatta 97.63 0.00e+00 890.00
IUUC-Meu-056782 Macropus eugenii 66.99 0.00e+00 629.00
IUUC-Mga-060112 Meleagris gallopavo 88.33 1.00e-172 599.00
IUUC-Mmr-061229 Microcebus murinus 89.27 0.00e+00 854.00
IUUC-Mdo-062397 Monodelphis domestica 75.23 0.00e+00 734.00
IUUC-Mmu-063764 Mus musculus 83.27 0.00e+00 816.00
IUUC-Mpu-066503 Mustela putorius furo 89.45 0.00e+00 865.00
IUUC-Mlu-068160 Myotis lucifugus 95.93 2.00e-98 350.00
IUUC-Nle-069170 Nomascus leucogenys 96.72 0.00e+00 901.00
IUUC-Ont-072082 Oreochromis niloticus 68.79 8.00e-133 466.00
IUUC-Oan-072715 Ornithorhynchus anatinus 73.03 0.00e+00 712.00
IUUC-Ocu-074747 Oryctolagus cuniculus 89.24 0.00e+00 782.00
IUUC-Ola-086646 Oryzias latipes 64.81 4.00e-128 451.00
IUUC-Oga-087995 Otolemur garnettii 89.86 0.00e+00 872.00
IUUC-Oar-089844 Ovis aries 85.53 0.00e+00 840.00
IUUC-Ptr-091556 Pan troglodytes 99.45 0.00e+00 908.00
IUUC-Pan-092224 Papio anubis 98.18 0.00e+00 890.00
IUUC-Psi-093856 Pelodiscus sinensis 89.33 0.00e+00 639.00
IUUC-Pma-094534 Petromyzon marinus 56.04 3.00e-101 361.00
IUUC-Pfo-096596 Poecilia formosa 62.13 8.00e-130 456.00
IUUC-Pca-100510 Procavia capensis 81.82 0.00e+00 804.00
IUUC-Pva-102962 Pteropus vampyrus 88.71 0.00e+00 785.00
IUUC-Rno-105696 Rattus norvegicus 82.91 0.00e+00 791.00
IUUC-Sha-106825 Sarcophilus harrisii 75.45 0.00e+00 736.00
IUUC-Ssc-116332 Sus scrofa 87.77 0.00e+00 819.00
IUUC-Tgu-117208 Taeniopygia guttata 88.89 2.00e-176 612.00
IUUC-Tru-118744 Takifugu rubripes 65.85 9.00e-132 462.00
IUUC-Tsy-119352 Tarsius syrichta 87.70 0.00e+00 859.00
IUUC-Tni-120413 Tetraodon nigroviridis 68.05 5.00e-130 457.00
IUUC-Tbe-127821 Tupaia belangeri 98.51 3.00e-121 429.00
IUUC-Ttr-128545 Tursiops truncatus 86.68 0.00e+00 796.00
IUUC-Vpa-130699 Vicugna pacos 97.26 0.00e+00 676.00
IUUC-Xtr-132207 Xenopus tropicalis 63.83 0.00e+00 627.00
Created Date 25-Jun-2017

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