iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gga-040891

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Cytokine-inducible SH2-containing protein

Genbank Nucleotide ID

AADN04000453

Gene Name

CISH

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000002260.4	ENSGALT00000003543.4	ENSGALP00000003536.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	1.30e-13	50.9	216	257

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 7    lrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           +r + +SLqhLCRl+I+rc++      +++LPLP+++ dYL+++++q
   Q: 216  RRDSIPSLQHLCRLRINRCTTE-----VERLPLPRRMGDYLKQYPFQ 257
           56789*****************.....7****************986 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MLFPWPRSDM ILCVPGPHPL LAEEKIQRLS LRGIAEDLTE HIMQPLPVPA FPEEPAPTFA 60
APEPDGSAPQ TRDPEEDLLC IAKTFSYLRE SGWYWGSITA SEAKQHLQKM PEGTFLVRDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGTCTCTCC CCAGCGCTCG CGGGGACCGT ATTTATTTCT TCCCGTCTAT TTATTATTAA 60
CGCCGAGCGC CCCGACCGCT TCTTTCTGAG AGCGCCCCGC GGGAGGATCG GACCGCGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028425--CIS
IPR000980--SH2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0005886--C:plasma membrane
GO:0035556--P:intracellular signal transduction
GO:0007205--P:protein kinase C-activating G-protein coupled receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001189	Ailuropoda melanoleuca	67.59	3.00e-82	297.00
IUUC-Aca-004372	Anolis carolinensis	76.83	4.00e-106	376.00
IUUC-Ame-010787	Astyanax mexicanus	48.19	4.00e-54	204.00
IUUC-Bta-012826	Bos taurus	65.23	6.00e-87	313.00
IUUC-Cja-020004	Callithrix jacchus	67.32	7.00e-83	300.00
IUUC-Cfa-020150	Canis familiaris	66.27	1.00e-80	292.00
IUUC-Csa-023173	Chlorocebus sabaeus	66.80	4.00e-83	300.00
IUUC-Dre-028606	Danio rerio	40.43	2.00e-35	142.00
IUUC-Dno-028956	Dasypus novemcinctus	64.59	2.00e-83	301.00
IUUC-Dor-030148	Dipodomys ordii	59.38	8.00e-74	269.00
IUUC-Ete-032313	Echinops telfairi	65.77	6.00e-80	290.00
IUUC-Eca-033422	Equus caballus	66.92	5.00e-88	317.00
IUUC-Eeu-034806	Erinaceus europaeus	66.40	7.00e-80	289.00
IUUC-Fca-036374	Felis catus	68.08	1.00e-88	318.00
IUUC-Fal-036801	Ficedula albicollis	86.05	2.00e-122	431.00
IUUC-Gmo-038483	Gadus morhua	44.79	2.00e-38	151.00
IUUC-Gac-042147	Gasterosteus aculeatus	41.11	6.00e-36	144.00
IUUC-Ggo-045511	Gorilla gorilla	66.02	1.00e-82	298.00
IUUC-Hsa-046678	Homo sapiens	66.15	3.00e-86	310.00
IUUC-Itr-048397	Ictidomys tridecemlineatus	67.69	6.00e-88	316.00
IUUC-Lch-050555	Latimeria chalumnae	61.20	2.00e-79	287.00
IUUC-Laf-054141	Loxodonta africana	67.18	6.00e-91	326.00
IUUC-Mcc-055401	Macaca mulatta	66.40	8.00e-83	299.00
IUUC-Meu-056592	Macropus eugenii	72.00	2.00e-85	308.00
IUUC-Mga-059515	Meleagris gallopavo	99.17	7.00e-118	416.00
IUUC-Mmr-060848	Microcebus murinus	65.77	4.00e-84	303.00
IUUC-Mdo-062720	Monodelphis domestica	72.44	5.00e-92	330.00
IUUC-Mmu-063348	Mus musculus	66.02	6.00e-87	313.00
IUUC-Mpu-065834	Mustela putorius furo	67.69	8.00e-84	303.00
IUUC-Mlu-067687	Myotis lucifugus	65.76	4.00e-78	283.00
IUUC-Nle-069277	Nomascus leucogenys	65.77	3.00e-85	307.00
IUUC-Ont-071890	Oreochromis niloticus	48.90	2.00e-37	148.00
IUUC-Oan-073672	Ornithorhynchus anatinus	76.77	9.00e-102	362.00
IUUC-Ocu-073875	Oryctolagus cuniculus	66.40	2.00e-81	295.00
IUUC-Ola-087140	Oryzias latipes	50.00	7.00e-28	115.00
IUUC-Oga-087943	Otolemur garnettii	67.31	5.00e-87	313.00
IUUC-Oar-090194	Ovis aries	65.46	2.00e-83	301.00
IUUC-Ptr-090934	Pan troglodytes	66.02	1.00e-83	302.00
IUUC-Pan-092121	Papio anubis	66.54	1.00e-86	312.00
IUUC-Psi-093733	Pelodiscus sinensis	79.34	1.00e-104	372.00
IUUC-Pfo-096313	Poecilia formosa	50.26	7.00e-45	172.00
IUUC-Pab-098439	Pongo abelii	66.54	2.00e-86	311.00
IUUC-Pca-101010	Procavia capensis	65.25	1.00e-88	319.00
IUUC-Pva-103112	Pteropus vampyrus	66.41	1.00e-86	312.00
IUUC-Rno-105917	Rattus norvegicus	66.02	4.00e-84	303.00
IUUC-Sha-106954	Sarcophilus harrisii	69.65	6.00e-92	330.00
IUUC-Sar-113001	Sorex araneus	66.40	9.00e-81	292.00
IUUC-Ssc-115922	Sus scrofa	73.43	3.00e-50	189.00
IUUC-Tgu-117338	Taeniopygia guttata	88.02	2.00e-116	411.00
IUUC-Tru-118511	Takifugu rubripes	46.39	8.00e-34	136.00
IUUC-Tsy-119434	Tarsius syrichta	67.59	1.00e-83	302.00
IUUC-Tni-119837	Tetraodon nigroviridis	44.62	2.00e-31	128.00
IUUC-Ttr-128340	Tursiops truncatus	54.33	3.00e-56	211.00
IUUC-Vpa-130443	Vicugna pacos	66.80	3.00e-88	317.00
IUUC-Xtr-131784	Xenopus tropicalis	58.33	1.00e-75	275.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence