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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-064382
Ensembl Protein ID ENSMUSP00000029907.5
UniProt Accession Q0KL01; Q8BGY8; Q8CCQ0; Q9CZA8; UBX2B_MOUSE
Genbank Protein ID BAF30880.1; BAB28494.1; BAC25851.1; BAC27819.1; BAC33515.1; CAM21532.1; AAH76632.1
Protein Name UBX domain-containing protein 2B; NSFL1 cofactor p37; p97 cofactor p37
Genbank Nucleotide ID AB120715; AK012822; AK028268; AK032332; AK049018; AL772385; BC076632
Gene Name Ubxn2b
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000028243.5 ENSMUST00000029907.5 ENSMUSP00000029907.5
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
Mentha
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTMPHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
ULD/UDP/UFD/UBX 8.20e-17 62.7 255 328
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   ULD/UDP/UFD/UBX
   S: 4    eqatlqiRlpdGkrlvrkFpssttleqiyqfve.yllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsll 78
           +++++qiRl+dG+rlv++F+s++++ ++++f+   +  +  + F Lv++fP ++l++e+   tlqea+++++ +l+
   Q: 255  PTTKIQIRLADGSRLVQRFNSTHRILDVRDFIVrSRPEFATTDFILVTSFPSKELTDETV--TLQEADILNTVILQ 328
           589******************************8888999999*****************..*********99985 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity (By similarity).
 Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity (By similarity).
Protein Sequence
(Fasta)
MAEGGRAEPE EQERGSSRPR PPSARDLQLA LAELYEDEMK CKSSKPDRST PATCRSPRTP 60
PHRLYSGDHK YDGLHIVQPP TGKIVNELFK EAREHGAVPL NEATRSSRED KTKSFTGGGY 120
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Protein Fasta Sequence


>IUUC-Mmu-064382|ULD,UBX|Mus musculus
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Nucleotide Sequence
(Fasta)
GGTCCGGGGC AGGCGCCGCA AGCGGGTGAA AGATGGCGGA GGGTGGCCGT GCGGAGCCGG 60
AGGAGCAGGA GCGTGGGTCC TCCAGGCCAC GGCCCCCAAG TGCGCGGGAC TTACAGGTGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-064382|ULD,UBX|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0256--Endoplasmic reticulum
KW-0333--Golgi apparatus
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR012989--SEP_domain
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom
PROSITE

PS51399--SEP
PS50033--UBX
Pfam

PF08059--SEP
PF00789--UBX
SMART

SM00553--SEP
SM00166--UBX
Gene Ontology

GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005794--C:Golgi apparatus
GO:0005634--C:nucleus
GO:0043130--F:ubiquitin binding
GO:0007030--P:Golgi organization
GO:0061025--P:membrane fusion
GO:0031468--P:nuclear envelope reassembly
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
KEGG mmu:68053
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000550 Aegilops tauschii 36.68 2.00e-35 142.00
IUUC-Aml-001637 Ailuropoda melanoleuca 86.10 1.00e-167 582.00
IUUC-Apl-003738 Anas platyrhynchos 71.86 1.00e-122 432.00
IUUC-Aca-005097 Anolis carolinensis 69.07 6.00e-124 436.00
IUUC-Ath-007064 Arabidopsis thaliana 36.50 4.00e-34 138.00
IUUC-Acl-008176 Aspergillus clavatus 39.11 2.00e-29 123.00
IUUC-Afl-008553 Aspergillus flavus 36.31 8.00e-26 111.00
IUUC-Aor-010016 Aspergillus oryzae 36.31 9.00e-26 110.00
IUUC-Bgr-012256 Blumeria graminis 34.95 1.00e-27 117.00
IUUC-Bta-012629 Bos taurus 85.11 5.00e-149 520.00
IUUC-Bdi-014204 Brachypodium distachyon 32.75 2.00e-33 136.00
IUUC-Bra-017734 Brassica rapa 35.64 2.00e-34 139.00
IUUC-Cja-019732 Callithrix jacchus 77.64 5.00e-135 473.00
IUUC-Cfa-021132 Canis familiaris 86.10 3.00e-168 584.00
IUUC-Cpo-021389 Cavia porcellus 85.90 3.00e-161 560.00
IUUC-Csa-023362 Chlorocebus sabaeus 85.50 5.00e-163 566.00
IUUC-Cgl-026628 Colletotrichum gloeosporioides 32.78 9.00e-24 104.00
IUUC-Dno-029956 Dasypus novemcinctus 84.68 4.00e-154 537.00
IUUC-Dor-031124 Dipodomys ordii 77.27 3.00e-130 457.00
IUUC-Eca-034063 Equus caballus 85.80 1.00e-167 582.00
IUUC-Fca-035606 Felis catus 85.80 1.00e-166 578.00
IUUC-Fal-036923 Ficedula albicollis 71.08 5.00e-121 427.00
IUUC-Ggr-039971 Gaeumannomyces graminis 28.50 1.00e-14 74.30
IUUC-Gga-040906 Gallus gallus 72.46 6.00e-137 480.00
IUUC-Gma-043511 Glycine max 34.67 5.00e-36 144.00
IUUC-Ggo-044801 Gorilla gorilla 86.04 2.00e-158 551.00
IUUC-Hsa-046853 Homo sapiens 86.04 2.00e-158 551.00
IUUC-Hvu-047203 Hordeum vulgare 33.07 1.00e-31 130.00
IUUC-Itr-047910 Ictidomys tridecemlineatus 91.22 6.00e-142 496.00
IUUC-Lpe-051122 Leersia perrieri 35.48 1.00e-34 140.00
IUUC-Lma-053319 Leptosphaeria maculans 39.39 1.00e-34 140.00
IUUC-Laf-053854 Loxodonta africana 82.59 5.00e-145 506.00
IUUC-Mcc-055607 Macaca mulatta 85.20 1.00e-158 552.00
IUUC-Mtr-058376 Medicago truncatula 37.91 3.00e-34 139.00
IUUC-Mga-059714 Meleagris gallopavo 72.78 2.00e-132 465.00
IUUC-Mmr-061091 Microcebus murinus 88.64 2.00e-162 564.00
IUUC-Mdo-062985 Monodelphis domestica 77.41 2.00e-139 488.00
IUUC-Mac-065403 Musa acuminata 38.66 1.00e-32 134.00
IUUC-Mpu-066168 Mustela putorius furo 87.34 2.00e-164 571.00
IUUC-Mlu-067562 Myotis lucifugus 83.38 5.00e-154 536.00
IUUC-Nfi-068609 Neosartorya fischeri 37.43 6.00e-29 121.00
IUUC-Ncr-068786 Neurospora crassa 33.70 4.00e-24 105.00
IUUC-Nle-069639 Nomascus leucogenys 86.04 9.00e-159 552.00
IUUC-Oan-073007 Ornithorhynchus anatinus 79.93 9.00e-144 502.00
IUUC-Ocu-074507 Oryctolagus cuniculus 85.80 1.00e-161 561.00
IUUC-Oba-075011 Oryza barthii 34.44 7.00e-34 137.00
IUUC-Obr-076164 Oryza brachyantha 36.62 2.00e-28 119.00
IUUC-Ogl-077805 Oryza glaberrima 34.44 7.00e-34 137.00
IUUC-Ogu-078942 Oryza glumaepatula 34.07 2.00e-34 139.00
IUUC-Oin-079497 Oryza indica 34.16 1.00e-33 137.00
IUUC-Olo-080254 Oryza longistaminata 37.04 6.00e-30 125.00
IUUC-Ome-081766 Oryza meridionalis 35.77 2.00e-31 131.00
IUUC-Oni-082258 Oryza nivara 34.44 7.00e-34 137.00
IUUC-Opu-083365 Oryza punctata 34.78 2.00e-35 143.00
IUUC-Oru-084748 Oryza rufipogon 34.07 2.00e-34 139.00
IUUC-Osa-085359 Oryza sativa 34.44 7.00e-34 137.00
IUUC-Oga-088292 Otolemur garnettii 75.90 9.00e-136 476.00
IUUC-Oar-090236 Ovis aries 83.82 2.00e-144 504.00
IUUC-Ptr-090664 Pan troglodytes 86.04 2.00e-158 551.00
IUUC-Pan-092072 Papio anubis 86.18 3.00e-157 547.00
IUUC-Psi-093486 Pelodiscus sinensis 76.05 3.00e-127 447.00
IUUC-Pno-094769 Phaeosphaeria nodorum 37.88 2.00e-34 140.00
IUUC-Pab-097813 Pongo abelii 86.04 2.00e-158 551.00
IUUC-Pca-100985 Procavia capensis 72.39 9.00e-102 363.00
IUUC-Ppe-101417 Prunus persica 34.66 2.00e-35 143.00
IUUC-Pva-102600 Pteropus vampyrus 86.11 1.00e-162 565.00
IUUC-Pte-104083 Pyrenophora teres 40.61 5.00e-40 158.00
IUUC-Pyt-104504 Pyrenophora triticirepentis 40.20 6.00e-35 141.00
IUUC-Rno-105047 Rattus norvegicus 91.88 5.00e-169 586.00
IUUC-Sha-106777 Sarcophilus harrisii 73.49 1.00e-66 245.00
IUUC-Sja-107717 Schizosaccharomyces japonicus 33.58 4.00e-31 129.00
IUUC-Sit-110328 Setaria italica 35.61 8.00e-34 138.00
IUUC-Sbi-114513 Sorghum bicolor 36.29 2.00e-35 143.00
IUUC-Sre-115176 Sporisorium reilianum 37.63 9.00e-32 131.00
IUUC-Ssc-115936 Sus scrofa 86.73 3.00e-148 517.00
IUUC-Tgu-116752 Taeniopygia guttata 71.85 8.00e-127 446.00
IUUC-Tsy-119015 Tarsius syrichta 75.97 3.00e-132 464.00
IUUC-Tca-121370 Theobroma cacao 33.10 5.00e-30 125.00
IUUC-Ttr-128760 Tursiops truncatus 85.94 6.00e-151 526.00
IUUC-Vpa-130155 Vicugna pacos 85.15 4.00e-146 510.00
IUUC-Vvi-131338 Vitis vinifera 33.10 3.00e-32 132.00
Created Date 25-Jun-2017

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