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Tag Content
UUCD2 ID IUUC-Aml-001742
UUCD1 version UUC-AiM-01057
Ensembl Protein ID ENSAMEP00000007685.1
UniProt Accession G1LL63; G1LL63_AILME
Genbank Protein ID ENSAMEP00000007685
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID ACTA01161100
Gene Name USP33
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSAMEG00000007257.1 ENSAMET00000008006.1 ENSAMEP00000007685.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 2.10e-114 382.3 185 717
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           tGlkN+gNtCYmN++LQ+Lsn+p+l++++l+     +   +++++k +++ks+ kl++elw ks+ ++v p++l++ +k++++ f+gy+
   Q: 185  TGLKNIGNTCYMNAALQALSNCPPLTQFFLD-----CGGLARTDKKPAICKSYLKLMTELWhKSRPGSVVPTTLFQGIKTVNPTFRGYS 268
           7******************************.....999999*******************99************************** PP
   S: 89   qqDaqEflaflldqleeelkk........eknkpkeeeeeedkselsde........................................ 129
           qqDaqEfl++l+d l+eelk+         ++ ++ee++eedks+++ +                                        
   Q: 269  QQDAQEFLRCLMDLLHEELKEqvmeveedPQTITTEETMEEDKSQSDVDfqscescsssdkaenengsrgfsednnettmliqddenns 357
           *******************8899998887777777777788877777779*************************************** PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 358  emskdwqkekmcnkinkvnsegeldkdrdsvsetvdlnnqetvkvqihsraseyitdvhlndlstsqilpsnegvnprlsasppksgnl 446
           ***************************************************************************************** PP
   S: 130  ...................aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke.............. 185
                              +++k++kk++s+isd+F+g++ s+++cl+cd+vs++ e+f+dlslp+pgke+ +k+              
   Q: 447  wpglapthkkvlaqsasspKRKKQHKKYRSVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLhssshptsivkags 535
           *******************9**************************************************99888************** PP
   S: 186  ...................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsf 239
                                              +lqdcL++f++++el+g+n+y+cekckk+++ +k +k++k+Pe+L++hLkRf  
   Q: 536  cgeayapqgwiaffmeyvkrfvvscvpswfwgpivTLQDCLAAFFARDELKGDNMYSCEKCKKLRNGVKFCKVQKFPEILCIHLKRF-- 622
           ***************************************************************************************.. PP
   S: 240  seeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleet 326
           ++e ++++ki+++v+fple Ldl+pf+++++  q   ++Y+L++v++H+G++ssGHY+ay++n+ ++ W++fdD++Vtev+e++v++  
   Q: 623  RHELMFSTKISTHVSFPLEgLDLQPFLAKDSPVQ--IVTYDLLSVICHHGTASSGHYIAYCRNNLNNlWYEFDDQSVTEVSESTVQN-- 707
           9999*************************77776..9**************************88889*******************.. PP
   S: 327  gstaYvlfYkr 337
            ++aYvlfY++
   Q: 708  -AEAYVLFYRK 717
           .********98 PP
   
Organism Ailuropoda melanoleuca
Protein Sequence
(Fasta)
INSVRLQSLV LTHKVLPHLE ILGRQEKISN RMAAFRNHCP HLDSVGEITK DDLIQKSHGT 60
CQDCKVRGPN LWACLENRCS YVGCGESQVD HSTIHSQETK HYLTVNLTTL RVWCYACSKE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Aml-001742|DUB,USP|Ailuropoda melanoleuca
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATCAATTCTG TTAGACTTCA GAGTCTTGTT CTTACCCATA AGATACATAG GTAGATCGAA 60
ATCCTTGTTC TGCCAAATGC TAACAATGGG AAGTCAGTCA GATTTGCCTC TCTTAGCCTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Aml-001742|DUB,USP|Ailuropoda melanoleuca
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF06337--DUSP
PF00443--UCH
PF02148--zf-UBP
SMART

SM00695--DUSP
SM00290--ZnF_UBP
Gene Ontology

GO:0005776--C:autophagosome
GO:0044297--C:cell body
GO:0005813--C:centrosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0007411--P:axon guidance
GO:0016477--P:cell migration
GO:0009267--P:cellular response to starvation
GO:0051298--P:centrosome duplication
GO:0032091--P:negative regulation of protein binding
GO:0032092--P:positive regulation of protein binding
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0050821--P:protein stabilization
GO:0010506--P:regulation of autophagy
GO:0008277--P:regulation of G-protein coupled receptor protein signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Apl-003987 Anas platyrhynchos 81.82 0.00e+00 1478.00
IUUC-Aca-004713 Anolis carolinensis 76.69 0.00e+00 1404.00
IUUC-Bta-013132 Bos taurus 97.27 0.00e+00 1785.00
IUUC-Cja-018811 Callithrix jacchus 96.16 0.00e+00 1806.00
IUUC-Cfa-021158 Canis familiaris 98.08 0.00e+00 1850.00
IUUC-Cpo-021910 Cavia porcellus 89.41 0.00e+00 1579.00
IUUC-Csa-023130 Chlorocebus sabaeus 97.05 0.00e+00 1775.00
IUUC-Cho-024383 Choloepus hoffmanni 79.30 0.00e+00 686.00
IUUC-Dre-028639 Danio rerio 69.80 0.00e+00 1239.00
IUUC-Dno-029416 Dasypus novemcinctus 94.32 0.00e+00 1716.00
IUUC-Ete-032994 Echinops telfairi 78.73 0.00e+00 861.00
IUUC-Eca-034248 Equus caballus 97.00 0.00e+00 1813.00
IUUC-Eeu-035357 Erinaceus europaeus 76.42 0.00e+00 1311.00
IUUC-Fca-036013 Felis catus 95.14 0.00e+00 1749.00
IUUC-Fal-037509 Ficedula albicollis 81.93 0.00e+00 1475.00
IUUC-Gmo-038944 Gadus morhua 65.13 0.00e+00 1178.00
IUUC-Gga-040647 Gallus gallus 81.70 0.00e+00 1464.00
IUUC-Gac-041752 Gasterosteus aculeatus 69.41 0.00e+00 1249.00
IUUC-Hsa-045694 Homo sapiens 96.06 0.00e+00 1795.00
IUUC-Itr-049041 Ictidomys tridecemlineatus 96.62 0.00e+00 1757.00
IUUC-Lch-050400 Latimeria chalumnae 70.61 0.00e+00 1267.00
IUUC-Loc-052616 Lepisosteus oculatus 70.19 0.00e+00 1320.00
IUUC-Laf-053493 Loxodonta africana 95.85 0.00e+00 1766.00
IUUC-Mcc-055542 Macaca mulatta 96.78 0.00e+00 1805.00
IUUC-Meu-056645 Macropus eugenii 73.97 0.00e+00 1303.00
IUUC-Mga-060019 Meleagris gallopavo 82.44 0.00e+00 1256.00
IUUC-Mmr-061241 Microcebus murinus 92.71 0.00e+00 1741.00
IUUC-Mmu-063786 Mus musculus 93.01 0.00e+00 1682.00
IUUC-Mpu-065772 Mustela putorius furo 98.01 0.00e+00 1488.00
IUUC-Mlu-067732 Myotis lucifugus 95.51 0.00e+00 1792.00
IUUC-Nle-069528 Nomascus leucogenys 95.52 0.00e+00 1775.00
IUUC-Opr-070606 Ochotona princeps 89.82 0.00e+00 1583.00
IUUC-Ont-071495 Oreochromis niloticus 70.59 0.00e+00 1256.00
IUUC-Oan-073695 Ornithorhynchus anatinus 84.47 0.00e+00 1043.00
IUUC-Ocu-074457 Oryctolagus cuniculus 93.49 0.00e+00 1728.00
IUUC-Ola-086739 Oryzias latipes 69.36 0.00e+00 1290.00
IUUC-Oga-088720 Otolemur garnettii 95.51 0.00e+00 1790.00
IUUC-Oar-089921 Ovis aries 96.38 0.00e+00 1808.00
IUUC-Ptr-090526 Pan troglodytes 96.06 0.00e+00 1795.00
IUUC-Pan-092396 Papio anubis 96.49 0.00e+00 1812.00
IUUC-Psi-092971 Pelodiscus sinensis 83.03 0.00e+00 1545.00
IUUC-Pfo-097415 Poecilia formosa 69.15 0.00e+00 1259.00
IUUC-Pab-098740 Pongo abelii 97.05 0.00e+00 1796.00
IUUC-Pca-100598 Procavia capensis 83.24 0.00e+00 900.00
IUUC-Pva-102820 Pteropus vampyrus 92.94 0.00e+00 1526.00
IUUC-Rno-104894 Rattus norvegicus 92.48 0.00e+00 1689.00
IUUC-Sce-106176 Saccharomyces cerevisiae 32.35 2.00e-25 111.00
IUUC-Sha-107244 Sarcophilus harrisii 78.35 0.00e+00 1405.00
IUUC-Sar-113665 Sorex araneus 93.35 0.00e+00 1770.00
IUUC-Ssc-115793 Sus scrofa 94.55 0.00e+00 1706.00
IUUC-Tgu-117487 Taeniopygia guttata 82.68 0.00e+00 1448.00
IUUC-Tru-117694 Takifugu rubripes 68.75 0.00e+00 1271.00
IUUC-Tsy-119598 Tarsius syrichta 83.35 0.00e+00 1483.00
IUUC-Tni-120189 Tetraodon nigroviridis 66.88 0.00e+00 1203.00
IUUC-Tbe-128125 Tupaia belangeri 84.77 2.00e-119 423.00
IUUC-Ttr-128269 Tursiops truncatus 92.39 0.00e+00 1659.00
IUUC-Vpa-130598 Vicugna pacos 94.43 0.00e+00 1754.00
IUUC-Xtr-132044 Xenopus tropicalis 74.76 0.00e+00 1313.00
Created Date 25-Jun-2017

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