iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034150

UUCD1 version

UUC-EqC-00291

Ensembl Protein ID

ENSECAP00000006668.1

UniProt Accession

F6UIQ7; F6UIQ7_HORSE

Protein Name

Uncharacterized protein

Gene Name

KLHL28

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000008626.1	ENSECAT00000008846.1	ENSECAP00000006668.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.50e-18	65.9	35	98
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.50e-12	46.5	134	165

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +D+il vg+++++ahk+vLa+ S++F+a+f+++l+e++ +++ve++ ++ ++++a++++ Ytg++
   Q: 35   CDIILRVGDVKIHAHKVVLASISPYFKAMFTGNLSEKE-NSEVEFQCIDETALQAIVEYAYTGTV 98
           8***********************************97.************************87 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           + Nc+gi rfA++y+c+dL++aa ++i+++F+
   Q: 134  PGNCIGISRFAETYGCHDLYLAATKYICQNFE 165
           56*****************************5 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MDHTSPTYML ANLTHLHSEQ LLQGLNLLRQ HHELCDIILR VGDVKIHAHK VVLASISPYF 60
KAMFTGNLSE KENSEVEFQC IDETALQAIV EYAYTGTVFI SQDTVESLLP AANLLQIKLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACCACA CATCCCCGAC CTACATGCTT GCTAACTTAA CCCACTTACA CTCTGAACAG 60
CTTCTGCAGG GCTTGAATCT CCTTCGTCAG CACCACGAAC TCTGTGACAT CATTCTTCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030569--KLHL28
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

KEGG

ecb:100063556

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001581	Ailuropoda melanoleuca	99.30	0.00e+00	1191.00
IUUC-Apl-003577	Anas platyrhynchos	92.97	0.00e+00	1089.00
IUUC-Aca-004320	Anolis carolinensis	86.95	0.00e+00	925.00
IUUC-Ame-011433	Astyanax mexicanus	84.76	0.00e+00	988.00
IUUC-Bta-012650	Bos taurus	99.82	0.00e+00	1194.00
IUUC-Cja-019878	Callithrix jacchus	98.77	0.00e+00	1192.00
IUUC-Cfa-020936	Canis familiaris	99.47	0.00e+00	1193.00
IUUC-Cpo-022212	Cavia porcellus	97.55	0.00e+00	1177.00
IUUC-Csa-023372	Chlorocebus sabaeus	99.12	0.00e+00	1192.00
IUUC-Cho-024885	Choloepus hoffmanni	98.66	1.00e-174	606.00
IUUC-Dno-029895	Dasypus novemcinctus	97.55	0.00e+00	1177.00
IUUC-Ete-032703	Echinops telfairi	97.99	0.00e+00	920.00
IUUC-Eeu-035233	Erinaceus europaeus	97.02	0.00e+00	1169.00
IUUC-Fca-036445	Felis catus	99.30	0.00e+00	1190.00
IUUC-Fal-037156	Ficedula albicollis	82.49	0.00e+00	997.00
IUUC-Gmo-039158	Gadus morhua	84.59	0.00e+00	1016.00
IUUC-Gga-040855	Gallus gallus	92.99	0.00e+00	1120.00
IUUC-Gac-041294	Gasterosteus aculeatus	83.89	0.00e+00	1007.00
IUUC-Ggo-045399	Gorilla gorilla	98.95	0.00e+00	1188.00
IUUC-Hsa-046199	Homo sapiens	98.95	0.00e+00	1188.00
IUUC-Itr-048859	Ictidomys tridecemlineatus	98.77	0.00e+00	1184.00
IUUC-Lch-049445	Latimeria chalumnae	88.59	0.00e+00	815.00
IUUC-Loc-052737	Lepisosteus oculatus	86.34	0.00e+00	1012.00
IUUC-Laf-054173	Loxodonta africana	98.60	0.00e+00	1180.00
IUUC-Mcc-055000	Macaca mulatta	99.12	0.00e+00	1191.00
IUUC-Meu-056028	Macropus eugenii	87.29	2.00e-145	509.00
IUUC-Mga-059609	Meleagris gallopavo	92.83	0.00e+00	1118.00
IUUC-Mmr-060842	Microcebus murinus	99.30	0.00e+00	1192.00
IUUC-Mdo-062776	Monodelphis domestica	93.17	0.00e+00	1089.00
IUUC-Mmu-063720	Mus musculus	97.20	0.00e+00	1176.00
IUUC-Mpu-066594	Mustela putorius furo	68.58	0.00e+00	732.00
IUUC-Mlu-067403	Myotis lucifugus	97.55	0.00e+00	1169.00
IUUC-Nle-069242	Nomascus leucogenys	98.77	0.00e+00	1186.00
IUUC-Opr-070942	Ochotona princeps	99.00	3.00e-177	613.00
IUUC-Ont-072586	Oreochromis niloticus	84.76	0.00e+00	1015.00
IUUC-Oan-073070	Ornithorhynchus anatinus	93.60	0.00e+00	1082.00
IUUC-Ocu-074536	Oryctolagus cuniculus	98.42	0.00e+00	1182.00
IUUC-Ola-086669	Oryzias latipes	71.33	0.00e+00	820.00
IUUC-Oga-088974	Otolemur garnettii	98.95	0.00e+00	1188.00
IUUC-Oar-089544	Ovis aries	99.65	0.00e+00	1195.00
IUUC-Ptr-091478	Pan troglodytes	98.60	0.00e+00	1179.00
IUUC-Pan-092653	Papio anubis	99.30	0.00e+00	1193.00
IUUC-Psi-094014	Pelodiscus sinensis	93.70	0.00e+00	1130.00
IUUC-Pfo-097316	Poecilia formosa	84.41	0.00e+00	1008.00
IUUC-Pab-098609	Pongo abelii	98.77	0.00e+00	1186.00
IUUC-Pva-102527	Pteropus vampyrus	99.00	5.00e-176	610.00
IUUC-Rno-105188	Rattus norvegicus	97.55	0.00e+00	1177.00
IUUC-Sha-106543	Sarcophilus harrisii	93.70	0.00e+00	1095.00
IUUC-Sar-113507	Sorex araneus	96.67	0.00e+00	1167.00
IUUC-Ssc-115803	Sus scrofa	99.12	0.00e+00	1188.00
IUUC-Tgu-116661	Taeniopygia guttata	81.94	0.00e+00	911.00
IUUC-Tru-118738	Takifugu rubripes	81.74	0.00e+00	981.00
IUUC-Tsy-119570	Tarsius syrichta	91.42	0.00e+00	1076.00
IUUC-Tni-120041	Tetraodon nigroviridis	83.19	0.00e+00	1003.00
IUUC-Tbe-127655	Tupaia belangeri	91.43	0.00e+00	1063.00
IUUC-Ttr-129249	Tursiops truncatus	99.82	0.00e+00	1194.00
IUUC-Vpa-130034	Vicugna pacos	99.12	0.00e+00	1189.00
IUUC-Xtr-132964	Xenopus tropicalis	87.92	0.00e+00	1065.00
IUUC-Xma-133894	Xiphophorus maculatus	84.24	0.00e+00	1007.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence