iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-028198

Ensembl Protein ID

ENSDARP00000021253.3

UniProt Accession

F1QEM3; F1QEM3_DANRE

Genbank Protein ID

AGD93127.1

Protein Name

Aurora kinase A

Genbank Nucleotide ID

CABZ01084472

Gene Name

aurka

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000012485.6	ENSDART00000008224.3	ENSDARP00000021253.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	61.48	5.00e-130	462.00	IUUC-Hsa-046968

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Danio rerio

Protein Sequence
(Fasta)

MDSGARSKSS RDLKIHRPEN EKVSAAGPKR VPVTQSVQKP VSNPHTRVLG AAQGPQRIQR 60
PVGKTSCPGD QNTRPEQHKP AAHSKPQPKP PLSAETNKTA EPSKQDKPHQ TPSSTTSTSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTATTTTAAA AGTGGGACAT TTGAAATTAA ACAGGTCGCA GTTGCAGGGC AGGATCGCGT 60
CGCCATCTGT AGAAAAGGAA ATATAGTTAT TAATAATTTT TCTCGATATT AAACCTCCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR030616--Aur
IPR030611--AURKA
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0032133--C:chromosome passenger complex
GO:0000780--C:condensed nuclear chromosome, centromeric region
GO:0005876--C:spindle microtubule
GO:0051233--C:spindle midzone
GO:0031616--C:spindle pole centrosome
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0000212--P:meiotic spindle organization
GO:0007100--P:mitotic centrosome separation
GO:0007067--P:mitotic nuclear division
GO:0007052--P:mitotic spindle organization
GO:0032465--P:regulation of cytokinesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000930	Aegilops tauschii	67.18	9.00e-106	376.00
IUUC-Aml-001426	Ailuropoda melanoleuca	62.03	2.00e-129	456.00
IUUC-Atr-002453	Amborella trichopoda	67.56	2.00e-107	382.00
IUUC-Apl-003626	Anas platyrhynchos	62.24	3.00e-135	475.00
IUUC-Aca-004602	Anolis carolinensis	60.88	5.00e-132	464.00
IUUC-Aly-005878	Arabidopsis lyrata	63.74	6.00e-103	367.00
IUUC-Ath-007117	Arabidopsis thaliana	64.12	5.00e-103	367.00
IUUC-Acl-008199	Aspergillus clavatus	55.22	1.00e-82	300.00
IUUC-Afl-008419	Aspergillus flavus	55.56	5.00e-82	298.00
IUUC-Afu-008751	Aspergillus fumigatus	55.68	5.00e-82	298.00
IUUC-Ani-009181	Aspergillus nidulans	54.10	2.00e-85	309.00
IUUC-Ang-009787	Aspergillus niger	54.21	5.00e-83	301.00
IUUC-Aor-009980	Aspergillus oryzae	55.56	5.00e-82	298.00
IUUC-Ate-010286	Aspergillus terreus	55.30	4.00e-82	298.00
IUUC-Ame-010849	Astyanax mexicanus	74.13	8.00e-175	606.00
IUUC-Bgr-012110	Blumeria graminis	58.71	2.00e-85	309.00
IUUC-Bta-013474	Bos taurus	62.21	3.00e-132	464.00
IUUC-Bci-013756	Botrytis cinerea	59.92	3.00e-92	332.00
IUUC-Bdi-014257	Brachypodium distachyon	67.18	2.00e-106	379.00
IUUC-Bol-016310	Brassica oleracea	64.89	5.00e-104	370.00
IUUC-Bra-017438	Brassica rapa	64.89	2.00e-104	372.00
IUUC-Cel-018157	Caenorhabditis elegans	60.16	2.00e-95	342.00
IUUC-Cja-019282	Callithrix jacchus	62.10	3.00e-129	454.00
IUUC-Cfa-020162	Canis familiaris	61.78	9.00e-131	459.00
IUUC-Cpo-021764	Cavia porcellus	61.60	5.00e-131	460.00
IUUC-Cre-022827	Chlamydomonas reinhardtii	65.27	1.00e-104	372.00
IUUC-Csa-023694	Chlorocebus sabaeus	78.24	5.00e-128	451.00
IUUC-Cho-024350	Choloepus hoffmanni	76.80	2.00e-90	324.00
IUUC-Cin-025542	Ciona intestinalis	70.70	2.00e-119	421.00
IUUC-Csv-025873	Ciona savignyi	71.92	8.00e-119	419.00
IUUC-Cgl-026632	Colletotrichum gloeosporioides	54.75	6.00e-79	287.00
IUUC-Cne-026928	Cryptococcus neoformans	63.42	6.00e-96	344.00
IUUC-Cme-027336	Cyanidioschyzon merolae	70.45	1.00e-116	413.00
IUUC-Dno-029928	Dasypus novemcinctus	61.90	1.00e-127	449.00
IUUC-Dor-030238	Dipodomys ordii	55.50	5.00e-113	400.00
IUUC-Dse-031266	Dothistroma septosporum	58.05	2.00e-88	319.00
IUUC-Dme-032007	Drosophila melanogaster	61.83	2.00e-101	362.00
IUUC-Ete-032911	Echinops telfairi	48.79	8.00e-86	310.00
IUUC-Eca-033749	Equus caballus	62.26	1.00e-129	456.00
IUUC-Eeu-035170	Erinaceus europaeus	58.04	1.00e-123	436.00
IUUC-Fca-035498	Felis catus	62.67	6.00e-132	464.00
IUUC-Fal-037397	Ficedula albicollis	79.32	9.00e-133	466.00
IUUC-Fox-037747	Fusarium oxysporum	59.09	1.00e-89	323.00
IUUC-Fso-038429	Fusarium solani	59.77	1.00e-88	320.00
IUUC-Gmo-039378	Gadus morhua	69.52	1.00e-151	529.00
IUUC-Ggr-039939	Gaeumannomyces graminis	60.23	9.00e-93	333.00
IUUC-Gga-040187	Gallus gallus	59.49	3.00e-133	468.00
IUUC-Gac-042223	Gasterosteus aculeatus	69.29	8.00e-165	573.00
IUUC-Gma-042870	Glycine max	65.27	4.00e-98	351.00
IUUC-Ggo-045617	Gorilla gorilla	60.65	4.00e-131	461.00
IUUC-Hsa-046968	Homo sapiens	61.48	2.00e-131	462.00
IUUC-Hvu-047072	Hordeum vulgare	51.91	5.00e-77	280.00
IUUC-Itr-048233	Ictidomys tridecemlineatus	53.08	8.00e-102	363.00
IUUC-Kpa-049093	Komagataella pastoris	54.05	3.00e-76	278.00
IUUC-Lch-050346	Latimeria chalumnae	61.75	1.00e-137	483.00
IUUC-Lpe-051466	Leersia perrieri	66.41	4.00e-105	374.00
IUUC-Lma-053006	Leptosphaeria maculans	58.17	9.00e-86	310.00
IUUC-Laf-053422	Loxodonta africana	62.01	1.00e-130	459.00
IUUC-Mcc-055245	Macaca mulatta	78.24	1.00e-127	449.00
IUUC-Mor-056952	Magnaporthe oryzae	59.09	8.00e-91	327.00
IUUC-Mpo-057605	Magnaporthe poae	60.23	6.00e-93	334.00
IUUC-Mtr-057726	Medicago truncatula	65.65	4.00e-105	374.00
IUUC-Mla-059174	Melampsora laricipopulina	65.38	6.00e-102	364.00
IUUC-Mga-059562	Meleagris gallopavo	71.49	2.00e-101	362.00
IUUC-Mvi-060305	Microbotryum violaceum	62.31	3.00e-93	335.00
IUUC-Mmr-061588	Microcebus murinus	62.34	6.00e-133	467.00
IUUC-Mdo-061914	Monodelphis domestica	58.96	1.00e-131	462.00
IUUC-Mmu-063288	Mus musculus	62.63	3.00e-134	471.00
IUUC-Mac-064969	Musa acuminata	64.89	7.00e-104	370.00
IUUC-Mpu-066855	Mustela putorius furo	62.30	7.00e-131	460.00
IUUC-Mlu-068046	Myotis lucifugus	62.20	2.00e-128	452.00
IUUC-Nfi-068527	Neosartorya fischeri	55.68	2.00e-82	299.00
IUUC-Ncr-068678	Neurospora crassa	58.11	2.00e-88	319.00
IUUC-Nle-069848	Nomascus leucogenys	60.70	1.00e-132	466.00
IUUC-Opr-070589	Ochotona princeps	79.01	2.00e-127	449.00
IUUC-Ont-071733	Oreochromis niloticus	69.38	6.00e-148	517.00
IUUC-Oan-073399	Ornithorhynchus anatinus	77.07	3.00e-130	457.00
IUUC-Ocu-074063	Oryctolagus cuniculus	64.08	6.00e-132	464.00
IUUC-Oba-075264	Oryza barthii	66.79	8.00e-105	373.00
IUUC-Obr-076048	Oryza brachyantha	66.41	2.00e-104	372.00
IUUC-Ogl-077637	Oryza glaberrima	66.79	1.00e-104	372.00
IUUC-Ogu-078830	Oryza glumaepatula	66.79	4.00e-105	374.00
IUUC-Oin-079150	Oryza indica	66.79	3.00e-105	374.00
IUUC-Olo-080398	Oryza longistaminata	55.70	3.00e-79	288.00
IUUC-Ome-081544	Oryza meridionalis	53.82	4.00e-86	311.00
IUUC-Oni-082250	Oryza nivara	66.79	3.00e-105	374.00
IUUC-Opu-083638	Oryza punctata	66.79	6.00e-105	373.00
IUUC-Oru-084981	Oryza rufipogon	66.79	3.00e-105	374.00
IUUC-Osa-085961	Oryza sativa	66.79	3.00e-105	374.00
IUUC-Olu-087880	Ostreococcus lucimarinus	67.05	3.00e-107	381.00
IUUC-Oga-088891	Otolemur garnettii	61.79	3.00e-131	461.00
IUUC-Oar-090021	Ovis aries	60.87	2.00e-129	455.00
IUUC-Ptr-091458	Pan troglodytes	61.22	3.00e-131	461.00
IUUC-Pan-092546	Papio anubis	78.63	3.00e-128	451.00
IUUC-Psi-093280	Pelodiscus sinensis	60.64	2.00e-130	459.00
IUUC-Pma-094298	Petromyzon marinus	76.34	4.00e-118	417.00
IUUC-Pno-094847	Phaeosphaeria nodorum	58.71	6.00e-87	314.00
IUUC-Ppa-095855	Physcomitrella patens	67.18	7.00e-109	386.00
IUUC-Pfo-096428	Poecilia formosa	67.52	1.00e-153	536.00
IUUC-Pab-098696	Pongo abelii	61.83	1.00e-129	456.00
IUUC-Pop-099405	Populus trichocarpa	65.65	2.00e-105	375.00
IUUC-Pca-100740	Procavia capensis	62.20	7.00e-130	457.00
IUUC-Ppe-101854	Prunus persica	66.03	1.00e-105	376.00
IUUC-Pva-103212	Pteropus vampyrus	62.06	1.00e-127	449.00
IUUC-Pgr-103474	Puccinia graminis	65.64	1.00e-101	363.00
IUUC-Ptt-103933	Puccinia triticina	48.65	1.00e-63	236.00
IUUC-Pte-104089	Pyrenophora teres	57.09	4.00e-87	315.00
IUUC-Pyt-104555	Pyrenophora triticirepentis	57.09	4.00e-87	315.00
IUUC-Rno-105057	Rattus norvegicus	62.83	1.00e-134	473.00
IUUC-Sha-107137	Sarcophilus harrisii	59.84	2.00e-132	466.00
IUUC-Sja-107767	Schizosaccharomyces japonicus	61.18	1.00e-95	343.00
IUUC-Spo-108078	Schizosaccharomyces pombe	62.60	6.00e-98	350.00
IUUC-Smo-109288	Selaginella moellendorffii	64.89	2.00e-104	372.00
IUUC-Sit-110246	Setaria italica	66.03	3.00e-104	371.00
IUUC-Sly-111379	Solanum lycopersicum	66.41	2.00e-105	375.00
IUUC-Stu-112777	Solanum tuberosum	65.65	8.00e-106	376.00
IUUC-Sbi-114325	Sorghum bicolor	66.41	1.00e-104	372.00
IUUC-Sre-115203	Sporisorium reilianum	56.44	3.00e-76	279.00
IUUC-Ssc-115361	Sus scrofa	62.47	6.00e-130	457.00
IUUC-Tgu-116967	Taeniopygia guttata	63.13	2.00e-130	458.00
IUUC-Tru-117570	Takifugu rubripes	71.61	8.00e-156	543.00
IUUC-Tsy-119280	Tarsius syrichta	75.50	2.00e-93	335.00
IUUC-Tni-120721	Tetraodon nigroviridis	70.10	8.00e-161	560.00
IUUC-Tca-121494	Theobroma cacao	65.65	1.00e-104	372.00
IUUC-Tre-121869	Trichoderma reesei	58.49	1.00e-87	316.00
IUUC-Tvi-122510	Trichoderma virens	58.87	6.00e-88	317.00
IUUC-Tae-123071	Triticum aestivum	67.18	9.00e-106	376.00
IUUC-Tur-126240	Triticum urartu	67.18	2.00e-105	375.00
IUUC-Tme-126921	Tuber melanosporum	60.08	6.00e-92	330.00
IUUC-Tbe-127872	Tupaia belangeri	58.36	3.00e-117	414.00
IUUC-Ttr-129134	Tursiops truncatus	62.97	6.00e-129	454.00
IUUC-Uma-129412	Ustilago maydis	56.23	1.00e-74	274.00
IUUC-Vda-130003	Verticillium dahliae	59.85	4.00e-91	328.00
IUUC-Vvi-131272	Vitis vinifera	66.03	1.00e-105	375.00
IUUC-Xtr-132019	Xenopus tropicalis	61.94	9.00e-139	486.00
IUUC-Xma-134203	Xiphophorus maculatus	66.20	3.00e-157	548.00
IUUC-Yli-134503	Yarrowia lipolytica	53.10	1.00e-84	306.00
IUUC-Zma-135232	Zea mays	65.65	3.00e-103	367.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence