iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-021703

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02010422

Gene Name

USP12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000005241.3	ENSCPOT00000005298.2	ENSCPOP00000004712.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.80e-98	329.2	24	353

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +Gl N+gNtCY+NSvLQ+L++++++re +l  +k++      + +k++ll++l++lf+++   k+k +++ p+++++ l+ke+e f++y
   Q: 24   FGLVNFGNTCYCNSVLQALYFCRPFREKVLA-YKSQ------PRKKENLLTCLADLFHSIAtqKKKVGVIPPKKFITRLRKENELFDNY 105
           6******************************.4444......456789************976777779******************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +qqDa+Efl++ll+++ + l++   ++k+e+++ +  + + ++e+++ +  +++++++Fqg+l+++++cl+c+++ss++e+fldls++v
   Q: 106  MQQDAHEFLNYLLNTIADILQE---ERKQEKQNGRLPNGNIDNENNNSTPDPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDV 191
           ********************44...444444444444555567888888899************************************* PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           ++++     s+++cL+ f+++e+l++e kyyce+c++kqea k++k+kklP +L lhLkRf++  + ++  k++ +v fpleL l  f+
   Q: 192  EQNT-----SITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYAKLSYRVVFPLELRL--FN 273
           ****.....9**********************************************************************66665..77 PP
   S: 266  tspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg.........staYvlfYkr 337
           ts +   + ++ Y+L+avvvH G +++ GHY+a+vk+ ++ WllfdD+ V++++ + ++e+ g         +++Y+lfY++
   Q: 274  TSGDA-TNPDRMYDLVAVVVHCGsGPNRGHYIAIVKS-HDFWLLFDDDIVEKIDAQAIEEFYGltsdisknsESGYILFYQS 353
           77444.4469***************************.555*******************999*****************97 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

QGANASALEK EIGPEQFPVN EHYFGLVNFG NTCYCNSVLQ ALYFCRPFRE KVLAYKSQPR 60
KKENLLTCLA DLFHSIATQK KKVGVIPPKK FITRLRKENE LFDNYMQQDA HEFLNYLLNT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGGCGCCA ATGCCTCGGC ATTAGAGAAA GAGATTGGTC CAGAACAGTT TCCAGTCAAC 60
GAGCACTATT TTGGATTAGT CAATGTGAGT ATCCACTGAA TATCCAGACA ACTGTCTGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001964	Ailuropoda melanoleuca	99.44	0.00e+00	739.00
IUUC-Apl-003411	Anas platyrhynchos	98.87	0.00e+00	709.00
IUUC-Aca-005212	Anolis carolinensis	98.02	0.00e+00	729.00
IUUC-Acl-008239	Aspergillus clavatus	49.00	4.00e-77	283.00
IUUC-Afl-008602	Aspergillus flavus	50.50	4.00e-79	289.00
IUUC-Afu-008816	Aspergillus fumigatus	49.83	2.00e-77	283.00
IUUC-Ani-009137	Aspergillus nidulans	48.48	2.00e-75	277.00
IUUC-Ang-009703	Aspergillus niger	49.33	2.00e-78	286.00
IUUC-Aor-009901	Aspergillus oryzae	50.50	3.00e-79	289.00
IUUC-Ate-010431	Aspergillus terreus	50.50	8.00e-78	285.00
IUUC-Ame-011015	Astyanax mexicanus	92.39	0.00e+00	681.00
IUUC-Bgr-012071	Blumeria graminis	43.71	4.00e-74	272.00
IUUC-Bta-012981	Bos taurus	98.87	0.00e+00	712.00
IUUC-Bci-013837	Botrytis cinerea	40.87	3.00e-73	269.00
IUUC-Cja-018831	Callithrix jacchus	99.44	0.00e+00	740.00
IUUC-Cfa-020534	Canis familiaris	99.15	0.00e+00	739.00
IUUC-Csa-023604	Chlorocebus sabaeus	99.38	0.00e+00	674.00
IUUC-Cho-024902	Choloepus hoffmanni	82.77	6.00e-165	573.00
IUUC-Cgl-026611	Colletotrichum gloeosporioides	42.90	1.00e-74	274.00
IUUC-Dre-027845	Danio rerio	93.24	0.00e+00	684.00
IUUC-Dno-029460	Dasypus novemcinctus	98.87	0.00e+00	738.00
IUUC-Dor-030972	Dipodomys ordii	99.22	3.00e-146	511.00
IUUC-Dse-031470	Dothistroma septosporum	47.90	6.00e-76	278.00
IUUC-Ete-033125	Echinops telfairi	77.89	3.00e-127	447.00
IUUC-Eca-033439	Equus caballus	99.44	0.00e+00	739.00
IUUC-Fca-035524	Felis catus	98.87	0.00e+00	734.00
IUUC-Fal-036833	Ficedula albicollis	97.75	0.00e+00	709.00
IUUC-Gmo-038763	Gadus morhua	92.70	0.00e+00	682.00
IUUC-Gga-041151	Gallus gallus	98.87	0.00e+00	709.00
IUUC-Gac-041967	Gasterosteus aculeatus	93.26	0.00e+00	685.00
IUUC-Hsa-045700	Homo sapiens	99.44	0.00e+00	740.00
IUUC-Itr-049082	Ictidomys tridecemlineatus	99.44	0.00e+00	739.00
IUUC-Lch-050435	Latimeria chalumnae	97.74	0.00e+00	710.00
IUUC-Loc-051968	Lepisosteus oculatus	95.76	0.00e+00	702.00
IUUC-Lma-053300	Leptosphaeria maculans	47.57	2.00e-78	287.00
IUUC-Laf-053887	Loxodonta africana	99.44	0.00e+00	740.00
IUUC-Mcc-055701	Macaca mulatta	99.44	0.00e+00	740.00
IUUC-Mga-059195	Meleagris gallopavo	98.87	0.00e+00	707.00
IUUC-Mmr-060751	Microcebus murinus	99.44	0.00e+00	740.00
IUUC-Mdo-062735	Monodelphis domestica	97.74	0.00e+00	705.00
IUUC-Mmu-063263	Mus musculus	98.31	0.00e+00	733.00
IUUC-Mlu-068128	Myotis lucifugus	99.44	0.00e+00	739.00
IUUC-Nfi-068611	Neosartorya fischeri	49.83	1.00e-77	284.00
IUUC-Ncr-068699	Neurospora crassa	44.63	4.00e-75	276.00
IUUC-Nle-069767	Nomascus leucogenys	99.44	0.00e+00	739.00
IUUC-Ont-072658	Oreochromis niloticus	93.54	0.00e+00	687.00
IUUC-Oan-073372	Ornithorhynchus anatinus	98.03	0.00e+00	733.00
IUUC-Ocu-074322	Oryctolagus cuniculus	99.15	0.00e+00	736.00
IUUC-Ola-087418	Oryzias latipes	93.54	0.00e+00	686.00
IUUC-Oga-088298	Otolemur garnettii	99.44	0.00e+00	741.00
IUUC-Oar-090269	Ovis aries	98.31	0.00e+00	709.00
IUUC-Ptr-090467	Pan troglodytes	99.44	0.00e+00	740.00
IUUC-Pan-092437	Papio anubis	99.15	0.00e+00	711.00
IUUC-Psi-092993	Pelodiscus sinensis	99.15	0.00e+00	740.00
IUUC-Pno-095044	Phaeosphaeria nodorum	47.85	2.00e-77	283.00
IUUC-Pfo-097052	Poecilia formosa	93.54	0.00e+00	687.00
IUUC-Pab-097797	Pongo abelii	99.44	0.00e+00	740.00
IUUC-Pca-100835	Procavia capensis	90.21	7.00e-168	582.00
IUUC-Pte-104356	Pyrenophora teres	47.87	2.00e-77	283.00
IUUC-Pyt-104709	Pyrenophora triticirepentis	48.20	1.00e-77	284.00
IUUC-Rno-106060	Rattus norvegicus	97.74	0.00e+00	709.00
IUUC-Sha-107087	Sarcophilus harrisii	99.44	0.00e+00	740.00
IUUC-Sja-107684	Schizosaccharomyces japonicus	43.73	3.00e-68	252.00
IUUC-Spo-108095	Schizosaccharomyces pombe	46.39	1.00e-75	277.00
IUUC-Sar-113216	Sorex araneus	98.87	0.00e+00	707.00
IUUC-Sre-115197	Sporisorium reilianum	50.18	7.00e-80	292.00
IUUC-Ssc-116321	Sus scrofa	98.59	0.00e+00	734.00
IUUC-Tgu-117482	Taeniopygia guttata	96.06	0.00e+00	697.00
IUUC-Tru-118613	Takifugu rubripes	93.54	0.00e+00	686.00
IUUC-Tsy-119520	Tarsius syrichta	88.63	4.00e-125	440.00
IUUC-Tni-120293	Tetraodon nigroviridis	93.54	0.00e+00	686.00
IUUC-Tre-122226	Trichoderma reesei	45.36	3.00e-75	276.00
IUUC-Tvi-122330	Trichoderma virens	45.54	5.00e-75	275.00
IUUC-Tbe-127783	Tupaia belangeri	98.31	0.00e+00	697.00
IUUC-Ttr-129083	Tursiops truncatus	99.15	0.00e+00	739.00
IUUC-Vda-129736	Verticillium dahliae	38.11	8.00e-57	215.00
IUUC-Vpa-130391	Vicugna pacos	94.35	0.00e+00	669.00
IUUC-Xtr-132464	Xenopus tropicalis	99.15	0.00e+00	711.00
IUUC-Xma-133475	Xiphophorus maculatus	93.54	0.00e+00	687.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence