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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063414
UUCD1 version UUC-MuM-01166
Ensembl Protein ID ENSMUSP00000095441.3
UniProt Accession B1AZ99; OTUD3_MOUSE
Genbank Protein ID EDL13286.1
Protein Name OTU domain-containing protein 3
Genbank Nucleotide ID AL929473
Gene Name Otud3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000041161.8 ENSMUST00000097830.3 ENSMUSP00000095441.3
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusPHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/UBA 82.91 5.00e-159 558.00 IUUC-Hsa-045794
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Mus musculus
Functional Description
(View)

Functional Description


     Deubiquitinating enzyme that hydrolyzes 'Lys-6'- and 'Lys-11'-linked polyubiquitin. Also hydrolyzes heterotypic (mixed and branched) and homotypic chains (By similarity).
 Deubiquitinating enzyme that hydrolyzes 'Lys-6'- and 'Lys-11'-linked polyubiquitin. Also hydrolyzes heterotypic (mixed and branched) and homotypic chains (By similarity).
Protein Sequence
(Fasta)
MSRKQAAKSR PGSGGRRAEA ERKRDERAAR RALAKERRNR PDPGGSGCEE EFVSFANQLQ 60
ALGLKLREVP GDGNCLFRAL GDQLEGHSRN HLKHRQETVD YMIRQREDFE PFVEDDIPFE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063414|UBD,UBA|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGGCGTCGTC CCCCTGCGCC GCTCCGCCCG GTGGCCGGCT GAGGCTGCGG CCCCGGGCTC 60
TGCGGCTCCG GCTCCGGCTT CGGCTCCTTC CGCGGCGAAG CCGTGTGCCG CCGCAGCCAT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063414|UBD,UBA|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
Interpro

IPR003323--OTU_dom
PROSITE

PS50802--OTU
Pfam

PF02338--OTU
Gene Ontology

GO:0005737--C:cytoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0051898--P:negative regulation of protein kinase B signaling
GO:0035871--P:protein K11-linked deubiquitination
GO:1990167--P:protein K27-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0044313--P:protein K6-linked deubiquitination
GO:0050821--P:protein stabilization
KEGG mmu:73162
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000676 Aegilops tauschii 32.40 6.00e-33 135.00
IUUC-Aml-001610 Ailuropoda melanoleuca 75.95 4.00e-126 444.00
IUUC-Atr-002622 Amborella trichopoda 37.10 1.00e-38 154.00
IUUC-Apl-004076 Anas platyrhynchos 55.65 2.00e-98 352.00
IUUC-Aly-006098 Arabidopsis lyrata 45.77 1.00e-35 143.00
IUUC-Ath-006727 Arabidopsis thaliana 45.77 2.00e-35 143.00
IUUC-Ame-010833 Astyanax mexicanus 73.74 2.00e-72 266.00
IUUC-Bta-013444 Bos taurus 81.41 8.00e-158 549.00
IUUC-Bdi-014363 Brachypodium distachyon 35.84 1.00e-40 160.00
IUUC-Bol-015165 Brassica oleracea 35.74 3.00e-36 145.00
IUUC-Bra-017512 Brassica rapa 46.48 1.00e-36 146.00
IUUC-Cja-019676 Callithrix jacchus 74.87 2.00e-137 481.00
IUUC-Cfa-020420 Canis familiaris 83.17 6.00e-160 556.00
IUUC-Cpo-021542 Cavia porcellus 81.66 1.00e-148 519.00
IUUC-Cre-022598 Chlamydomonas reinhardtii 35.89 5.00e-34 138.00
IUUC-Csa-024221 Chlorocebus sabaeus 83.42 4.00e-165 574.00
IUUC-Cho-024571 Choloepus hoffmanni 63.24 5.00e-68 251.00
IUUC-Cin-025437 Ciona intestinalis 40.86 7.00e-58 217.00
IUUC-Cne-027062 Cryptococcus neoformans 46.15 2.00e-11 63.20
IUUC-Cme-027120 Cyanidioschyzon merolae 32.43 3.00e-19 88.20
IUUC-Dre-027837 Danio rerio 76.26 1.00e-75 276.00
IUUC-Dno-029992 Dasypus novemcinctus 81.86 6.00e-157 546.00
IUUC-Dor-031023 Dipodomys ordii 68.81 2.00e-103 369.00
IUUC-Dse-031192 Dothistroma septosporum 28.11 2.00e-18 87.00
IUUC-Ete-032971 Echinops telfairi 58.69 4.00e-90 325.00
IUUC-Eca-034055 Equus caballus 83.53 7.00e-155 540.00
IUUC-Eeu-035085 Erinaceus europaeus 62.34 8.00e-49 187.00
IUUC-Fca-035510 Felis catus 80.92 6.00e-133 466.00
IUUC-Fal-037522 Ficedula albicollis 57.06 3.00e-105 374.00
IUUC-Gmo-038654 Gadus morhua 70.71 2.00e-72 265.00
IUUC-Gga-040831 Gallus gallus 61.03 1.00e-94 340.00
IUUC-Gac-042037 Gasterosteus aculeatus 73.23 9.00e-70 257.00
IUUC-Gma-043851 Glycine max 36.00 3.00e-33 135.00
IUUC-Ggo-045446 Gorilla gorilla 73.06 5.00e-138 484.00
IUUC-Hsa-045794 Homo sapiens 82.91 2.00e-164 571.00
IUUC-Hvu-047137 Hordeum vulgare 37.10 2.00e-37 149.00
IUUC-Itr-048577 Ictidomys tridecemlineatus 82.52 2.00e-145 508.00
IUUC-Lch-049440 Latimeria chalumnae 54.75 3.00e-90 325.00
IUUC-Lpe-050983 Leersia perrieri 37.23 9.00e-37 147.00
IUUC-Loc-052084 Lepisosteus oculatus 51.60 1.00e-72 266.00
IUUC-Laf-054509 Loxodonta africana 84.13 8.00e-167 579.00
IUUC-Mcc-055100 Macaca mulatta 72.88 3.00e-59 220.00
IUUC-Meu-056580 Macropus eugenii 64.74 9.00e-101 360.00
IUUC-Mtr-057856 Medicago truncatula 33.95 1.00e-33 137.00
IUUC-Mga-060062 Meleagris gallopavo 54.63 7.00e-94 337.00
IUUC-Mmr-060638 Microcebus murinus 82.91 3.00e-159 554.00
IUUC-Mdo-062294 Monodelphis domestica 69.80 4.00e-136 477.00
IUUC-Mac-065203 Musa acuminata 43.70 2.00e-25 110.00
IUUC-Mpu-066357 Mustela putorius furo 82.91 1.00e-158 552.00
IUUC-Mlu-068043 Myotis lucifugus 80.64 2.00e-153 535.00
IUUC-Nle-069696 Nomascus leucogenys 83.53 9.00e-163 566.00
IUUC-Opr-070471 Ochotona princeps 68.62 1.00e-107 382.00
IUUC-Ont-071796 Oreochromis niloticus 59.57 5.00e-74 271.00
IUUC-Oan-073053 Ornithorhynchus anatinus 71.83 5.00e-96 343.00
IUUC-Ocu-074959 Oryctolagus cuniculus 78.70 1.00e-148 519.00
IUUC-Oba-075820 Oryza barthii 38.36 2.00e-29 123.00
IUUC-Obr-076818 Oryza brachyantha 38.39 5.00e-39 155.00
IUUC-Ogl-077295 Oryza glaberrima 38.36 2.00e-29 123.00
IUUC-Ogu-078220 Oryza glumaepatula 37.50 1.00e-27 117.00
IUUC-Oin-080176 Oryza indica 37.93 2.00e-29 123.00
IUUC-Olo-081061 Oryza longistaminata 33.07 4.00e-18 85.90
IUUC-Ome-082004 Oryza meridionalis 36.80 2.00e-28 119.00
IUUC-Oni-082169 Oryza nivara 33.77 1.00e-18 87.80
IUUC-Opu-083319 Oryza punctata 36.48 1.00e-28 120.00
IUUC-Oru-084638 Oryza rufipogon 37.93 3.00e-29 122.00
IUUC-Osa-085511 Oryza sativa 47.55 2.00e-26 112.00
IUUC-Ola-086377 Oryzias latipes 71.21 1.00e-74 273.00
IUUC-Olu-087677 Ostreococcus lucimarinus 36.69 4.00e-18 85.10
IUUC-Oga-087948 Otolemur garnettii 75.38 8.00e-134 469.00
IUUC-Oar-089738 Ovis aries 75.78 3.00e-138 484.00
IUUC-Ptr-091573 Pan troglodytes 83.17 3.00e-165 574.00
IUUC-Pan-092308 Papio anubis 84.63 2.00e-168 585.00
IUUC-Psi-093215 Pelodiscus sinensis 61.95 1.00e-85 309.00
IUUC-Pno-095148 Phaeosphaeria nodorum 32.95 1.00e-11 63.90
IUUC-Ppa-095671 Physcomitrella patens 44.52 8.00e-34 139.00
IUUC-Pfo-096080 Poecilia formosa 71.21 3.00e-71 261.00
IUUC-Pab-098297 Pongo abelii 81.29 5.00e-147 514.00
IUUC-Pop-099083 Populus trichocarpa 35.15 2.00e-36 145.00
IUUC-Pca-100767 Procavia capensis 72.14 5.00e-122 430.00
IUUC-Pva-103136 Pteropus vampyrus 78.14 4.00e-150 524.00
IUUC-Pgr-103365 Puccinia graminis 36.63 1.00e-13 71.20
IUUC-Rno-105390 Rattus norvegicus 89.42 2.00e-177 614.00
IUUC-Sha-106882 Sarcophilus harrisii 75.08 5.00e-122 430.00
IUUC-Ssl-108547 Sclerotinia sclerotiorum 27.74 1.00e-12 67.00
IUUC-Sit-109684 Setaria italica 37.97 7.00e-41 160.00
IUUC-Sly-111374 Solanum lycopersicum 43.54 8.00e-34 137.00
IUUC-Stu-112721 Solanum tuberosum 44.00 2.00e-35 142.00
IUUC-Sar-113367 Sorex araneus 78.70 2.00e-137 481.00
IUUC-Sbi-114765 Sorghum bicolor 36.44 1.00e-40 160.00
IUUC-Sre-115174 Sporisorium reilianum 36.14 3.00e-17 83.60
IUUC-Tgu-116990 Taeniopygia guttata 64.75 7.00e-94 336.00
IUUC-Tru-118145 Takifugu rubripes 48.38 9.00e-73 267.00
IUUC-Tsy-119102 Tarsius syrichta 79.94 6.00e-128 450.00
IUUC-Tni-119708 Tetraodon nigroviridis 71.21 6.00e-71 261.00
IUUC-Tca-121225 Theobroma cacao 33.17 5.00e-24 105.00
IUUC-Tae-123104 Triticum aestivum 37.56 2.00e-38 153.00
IUUC-Tur-126073 Triticum urartu 37.10 1.00e-37 150.00
IUUC-Tbe-127957 Tupaia belangeri 91.88 1.00e-67 249.00
IUUC-Ttr-128820 Tursiops truncatus 88.13 2.00e-126 446.00
IUUC-Uma-129319 Ustilago maydis 36.14 4.00e-18 86.70
IUUC-Vpa-130646 Vicugna pacos 65.75 6.00e-100 357.00
IUUC-Vvi-131263 Vitis vinifera 44.37 7.00e-34 137.00
IUUC-Xtr-132318 Xenopus tropicalis 48.70 2.00e-76 279.00
IUUC-Xma-133918 Xiphophorus maculatus 71.21 2.00e-71 262.00
IUUC-Yli-134572 Yarrowia lipolytica 35.80 1.00e-20 94.00
IUUC-Zma-134975 Zea mays 36.94 3.00e-40 159.00
Created Date 25-Jun-2017

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