iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-022286

Ensembl Protein ID

ENSCPOP00000019315.1

UniProt Accession

H0W8K9; H0W8K9_CAVPO

Genbank Protein ID

ENSCPOP00000019315

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AAKN02008495

Gene Name

ING1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000020570.1	ENSCPOT00000022053.1	ENSCPOP00000019315.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	8.60e-09	35.4	263	310

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 263  TYC-LCNQVSYGE--MIGCDNeeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 310
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

PETATRPTSG AKLAPGKTRW PPPQFPVHER STPRPISPLA PAALDKWWGV SKPLPGLWTQ 60
GDGLSGIHSP RPSGPGWSQG SQMWVLKALC NSLFLFAEIL KELDEYYEKF KRETDGTQKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGAGACAG CCACCAGACC CACATCCGGG GCAAAACTGG CCCCAGGGAA GACACGATGG 60
CCCCCTCCCC AGGTCCAGCC ATGCCTGTCT GCCCCTCGCA CTGGGAGGTG CAGCCCAGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006606--P:protein import into nucleus
GO:0010941--P:regulation of cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	92.37	2.00e-102	364.00
IUUC-Apl-003910	Anas platyrhynchos	91.06	2.00e-98	351.00
IUUC-Aca-004874	Anolis carolinensis	90.68	1.00e-97	348.00
IUUC-Acl-008091	Aspergillus clavatus	52.11	8.00e-19	89.00
IUUC-Ame-011262	Astyanax mexicanus	67.21	5.00e-75	273.00
IUUC-Bta-013507	Bos taurus	88.46	3.00e-90	324.00
IUUC-Cja-018925	Callithrix jacchus	87.71	2.00e-95	342.00
IUUC-Cfa-020947	Canis familiaris	91.95	5.00e-101	360.00
IUUC-Csa-023825	Chlorocebus sabaeus	87.29	7.00e-95	340.00
IUUC-Cho-024577	Choloepus hoffmanni	94.42	5.00e-101	360.00
IUUC-Cne-027005	Cryptococcus neoformans	44.59	5.00e-16	78.60
IUUC-Dno-029834	Dasypus novemcinctus	93.22	2.00e-102	364.00
IUUC-Dor-030315	Dipodomys ordii	89.36	9.00e-108	383.00
IUUC-Ete-032408	Echinops telfairi	69.73	2.00e-94	338.00
IUUC-Eca-034244	Equus caballus	93.16	6.00e-102	363.00
IUUC-Fca-035391	Felis catus	90.87	5.00e-93	333.00
IUUC-Fal-036838	Ficedula albicollis	90.25	5.00e-98	350.00
IUUC-Gga-040619	Gallus gallus	89.83	1.00e-97	348.00
IUUC-Ggo-045481	Gorilla gorilla	73.55	2.00e-101	362.00
IUUC-Hsa-046170	Homo sapiens	74.20	3.00e-101	361.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	94.87	1.00e-102	365.00
IUUC-Lch-050397	Latimeria chalumnae	85.59	2.00e-93	334.00
IUUC-Loc-052038	Lepisosteus oculatus	81.00	4.00e-81	294.00
IUUC-Laf-054126	Loxodonta africana	93.64	3.00e-103	367.00
IUUC-Mcc-055031	Macaca mulatta	70.30	7.00e-99	353.00
IUUC-Meu-056248	Macropus eugenii	91.95	5.00e-98	350.00
IUUC-Mga-059217	Meleagris gallopavo	88.33	9.00e-97	346.00
IUUC-Mmr-061581	Microcebus murinus	93.22	6.00e-103	366.00
IUUC-Mdo-062452	Monodelphis domestica	91.53	2.00e-99	355.00
IUUC-Mmu-063412	Mus musculus	91.53	2.00e-100	358.00
IUUC-Mpu-066479	Mustela putorius furo	93.19	4.00e-102	364.00
IUUC-Mlu-067723	Myotis lucifugus	93.64	3.00e-103	367.00
IUUC-Nle-069122	Nomascus leucogenys	86.86	2.00e-94	338.00
IUUC-Opr-070835	Ochotona princeps	84.12	5.00e-84	303.00
IUUC-Ont-071606	Oreochromis niloticus	57.63	1.00e-67	249.00
IUUC-Oan-073023	Ornithorhynchus anatinus	88.98	2.00e-94	338.00
IUUC-Ocu-073779	Oryctolagus cuniculus	87.04	6.00e-93	333.00
IUUC-Ola-086891	Oryzias latipes	62.71	3.00e-74	271.00
IUUC-Oga-087954	Otolemur garnettii	91.53	2.00e-100	358.00
IUUC-Oar-090006	Ovis aries	88.14	4.00e-96	343.00
IUUC-Ptr-090589	Pan troglodytes	87.29	5.00e-95	340.00
IUUC-Pan-091896	Papio anubis	71.74	1.00e-103	369.00
IUUC-Psi-093266	Pelodiscus sinensis	91.10	7.00e-99	353.00
IUUC-Pma-094265	Petromyzon marinus	74.67	2.00e-33	134.00
IUUC-Pfo-097531	Poecilia formosa	58.69	6.00e-72	263.00
IUUC-Pab-098253	Pongo abelii	87.29	7.00e-95	339.00
IUUC-Pva-102753	Pteropus vampyrus	89.32	1.00e-89	323.00
IUUC-Rno-105964	Rattus norvegicus	91.88	2.00e-89	321.00
IUUC-Sha-107270	Sarcophilus harrisii	91.10	1.00e-98	352.00
IUUC-Tgu-116822	Taeniopygia guttata	90.68	2.00e-98	352.00
IUUC-Tni-119980	Tetraodon nigroviridis	58.94	6.00e-72	263.00
IUUC-Tre-121950	Trichoderma reesei	64.29	9.00e-20	92.40
IUUC-Tvi-122341	Trichoderma virens	60.71	1.00e-15	75.50
IUUC-Ttr-128672	Tursiops truncatus	88.84	1.00e-99	355.00
IUUC-Xtr-132200	Xenopus tropicalis	82.20	1.00e-88	319.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence