iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Spo-108033

UUCD1 version

UUC-ScP-00053

Ensembl Protein ID

SPBC409.05.1:pep

UniProt Accession

Q9Y709; SKP1_SCHPO

Genbank Protein ID

BAA77790.1; BAB62325.1; AAD37024.1; CAB52607.1

Protein Name

Suppressor of kinetochore protein 1; P19/Skp1 homolog

Genbank Nucleotide ID

AB027472; AB067633; AF071066; CU329671

Gene Name

skp1; psh1; sph1; SPBC409.05

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPBC409.05	SPBC409.05.1	SPBC409.05.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	HINT	Mentha
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/SCF/SKP1	SKP1	15147268

Classification

Family	E-value	Score	Start	End
E3 adaptor/Cullin RING/SCF/SKP1	5.60e-31	104.6	111	158

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/SKP1

   S: 1    ksLLdltcktVadmikgktpeeiRktFnienDftpeEeakvReEnqWA 48
           k+LLd++cktVa+mi+gk+pe+iRktFni nDftpeEe+++R+En+WA
   Q: 111  KPLLDTGCKTVANMIRGKSPEDIRKTFNIPNDFTPEEEEQIRKENEWA 158
           79*********************************************9 PP

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Required for cig2 degradation in the G2 and M phases of the cell cycle. Together with pof6, essential for septum processing and cell separation. Involved in mitotic progression, essential for the execution of anaphase B; required for coordinated structural alterations of mitotic spindles and segregation of nuclear membrane structures at anaphase. Involved in the DNA damage checkpoint pathway and maintenance of genome integrity. Component of the RAVE complex which is required for stable assembly of the vacuolar ATPase complex V-ATPase.

Protein Sequence
(Fasta)

MSKIKLISSD NEEFVVDQLI AERSMLIKNM LEDVGEINVP IPLPNVSSNV LRKVLEWCEH 60
HKNDLYSGTE EESDIRLKKS TDIDEWDRKF MAVDQEMLFE IVLASNYLDI KPLLDTGCKT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCATAACT AGAAATGCTA ACAGCTTAAC TTTCATTCAT CCATTACTTA CATACATCAA 60
CAATGTCCAA AATCAAACTG ATTTCATCTG ACAATGAAGA GTTCGTGGTC GGTATGTAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0227--DNA damage
KW-0498--Mitosis
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR016897--SKP1
IPR001232--SKP1-like
IPR011333--SKP1/BTB/POZ
IPR016072--Skp1_comp_dimer
IPR016073--Skp1_comp_POZ

Pfam

PF01466--Skp1
PF03931--Skp1_POZ

SMART

SM00512--Skp1

Gene Ontology

GO:0005829--C:cytosol
GO:0043224--C:nuclear SCF ubiquitin ligase complex
GO:0005634--C:nucleus
GO:0043291--C:RAVE complex
GO:0019005--C:SCF ubiquitin ligase complex
GO:0017117--C:single-stranded DNA-dependent ATP-dependent DNA helicase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0000920--P:cell separation after cytokinesis
GO:0006974--P:cellular response to DNA damage stimulus
GO:0007067--P:mitotic nuclear division
GO:0045841--P:negative regulation of mitotic metaphase/anaphase transition
GO:0006998--P:nuclear envelope organization
GO:0030163--P:protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0007346--P:regulation of mitotic cell cycle
GO:0060542--P:regulation of strand invasion
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

spo:SPBC409.05

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000465	Aegilops tauschii	50.97	1.00e-38	150.00
IUUC-Aml-002023	Ailuropoda melanoleuca	56.36	8.00e-43	164.00
IUUC-Atr-002858	Amborella trichopoda	53.21	2.00e-33	132.00
IUUC-Apl-003393	Anas platyrhynchos	56.36	8.00e-43	164.00
IUUC-Aca-004709	Anolis carolinensis	56.36	8.00e-43	164.00
IUUC-Aly-006236	Arabidopsis lyrata	49.69	2.00e-38	149.00
IUUC-Ath-007456	Arabidopsis thaliana	50.32	2.00e-39	152.00
IUUC-Ago-007847	Ashbya gossypii	53.14	3.00e-49	185.00
IUUC-Acl-008178	Aspergillus clavatus	69.18	1.00e-60	223.00
IUUC-Afl-008452	Aspergillus flavus	70.25	3.00e-61	224.00
IUUC-Afu-008785	Aspergillus fumigatus	69.38	3.00e-61	224.00
IUUC-Ani-009312	Aspergillus nidulans	69.87	2.00e-59	219.00
IUUC-Aor-010012	Aspergillus oryzae	70.25	3.00e-61	224.00
IUUC-Ate-010375	Aspergillus terreus	70.32	4.00e-60	221.00
IUUC-Ame-011025	Astyanax mexicanus	56.36	6.00e-43	164.00
IUUC-Bgr-012280	Blumeria graminis	65.07	2.00e-45	172.00
IUUC-Bta-013519	Bos taurus	56.36	8.00e-43	164.00
IUUC-Bci-013888	Botrytis cinerea	67.48	3.00e-41	158.00
IUUC-Bdi-014547	Brachypodium distachyon	49.68	4.00e-32	128.00
IUUC-Bol-015842	Brassica oleracea	51.28	3.00e-37	145.00
IUUC-Bra-017558	Brassica rapa	49.04	4.00e-38	148.00
IUUC-Cel-018653	Caenorhabditis elegans	56.44	6.00e-45	171.00
IUUC-Cja-019785	Callithrix jacchus	56.13	3.00e-38	149.00
IUUC-Cfa-020931	Canis familiaris	56.36	1.00e-42	163.00
IUUC-Cpo-022487	Cavia porcellus	55.76	1.00e-40	156.00
IUUC-Cre-022751	Chlamydomonas reinhardtii	50.94	1.00e-38	150.00
IUUC-Csa-023459	Chlorocebus sabaeus	55.76	2.00e-42	162.00
IUUC-Cho-024854	Choloepus hoffmanni	43.75	6.00e-11	57.80
IUUC-Cin-025538	Ciona intestinalis	53.05	2.00e-40	155.00
IUUC-Csv-025865	Ciona savignyi	53.05	1.00e-42	163.00
IUUC-Cgl-026548	Colletotrichum gloeosporioides	68.92	4.00e-55	204.00
IUUC-Cne-027058	Cryptococcus neoformans	65.82	1.00e-59	220.00
IUUC-Cme-027174	Cyanidioschyzon merolae	45.22	1.00e-33	133.00
IUUC-Dre-027756	Danio rerio	56.36	6.00e-43	164.00
IUUC-Dno-028924	Dasypus novemcinctus	56.36	8.00e-43	164.00
IUUC-Dor-030847	Dipodomys ordii	52.44	2.00e-37	146.00
IUUC-Dse-031209	Dothistroma septosporum	70.44	2.00e-60	223.00
IUUC-Dme-032028	Drosophila melanogaster	56.71	1.00e-46	176.00
IUUC-Ete-033117	Echinops telfairi	54.55	2.00e-41	159.00
IUUC-Eca-033320	Equus caballus	56.36	8.00e-43	164.00
IUUC-Eeu-034817	Erinaceus europaeus	59.09	7.00e-11	56.20
IUUC-Fca-035423	Felis catus	56.36	8.00e-43	164.00
IUUC-Fal-036956	Ficedula albicollis	56.36	8.00e-43	164.00
IUUC-Fox-037761	Fusarium oxysporum	69.39	4.00e-56	208.00
IUUC-Fso-038451	Fusarium solani	66.89	3.00e-56	208.00
IUUC-Gmo-039178	Gadus morhua	56.36	8.00e-43	164.00
IUUC-Ggr-039831	Gaeumannomyces graminis	65.54	1.00e-53	199.00
IUUC-Gga-040238	Gallus gallus	56.36	8.00e-43	164.00
IUUC-Gac-041965	Gasterosteus aculeatus	56.36	8.00e-43	164.00
IUUC-Gma-043086	Glycine max	51.92	2.00e-36	142.00
IUUC-Ggo-045025	Gorilla gorilla	56.36	8.00e-43	164.00
IUUC-Hsa-046875	Homo sapiens	56.36	8.00e-43	164.00
IUUC-Hvu-047497	Hordeum vulgare	48.72	3.00e-34	135.00
IUUC-Itr-047900	Ictidomys tridecemlineatus	55.15	3.00e-42	162.00
IUUC-Kpa-049138	Komagataella pastoris	54.05	7.00e-51	191.00
IUUC-Lch-050522	Latimeria chalumnae	55.83	2.00e-45	172.00
IUUC-Lpe-051330	Leersia perrieri	50.00	4.00e-39	151.00
IUUC-Loc-052596	Lepisosteus oculatus	56.36	8.00e-43	164.00
IUUC-Lma-053020	Leptosphaeria maculans	65.03	3.00e-45	172.00
IUUC-Laf-053847	Loxodonta africana	56.36	8.00e-43	164.00
IUUC-Mor-057176	Magnaporthe oryzae	66.89	8.00e-55	204.00
IUUC-Mpo-057471	Magnaporthe poae	65.54	1.00e-53	199.00
IUUC-Mtr-058458	Medicago truncatula	45.51	2.00e-37	146.00
IUUC-Mla-059153	Melampsora laricipopulina	70.25	9.00e-61	223.00
IUUC-Mga-059864	Meleagris gallopavo	56.36	8.00e-43	164.00
IUUC-Mvi-060342	Microbotryum violaceum	70.62	1.00e-63	233.00
IUUC-Mdo-062509	Monodelphis domestica	56.36	8.00e-43	164.00
IUUC-Mmu-063694	Mus musculus	56.36	8.00e-43	164.00
IUUC-Mac-064626	Musa acuminata	50.94	1.00e-35	140.00
IUUC-Mpu-065990	Mustela putorius furo	56.36	8.00e-43	164.00
IUUC-Mlu-068168	Myotis lucifugus	56.36	8.00e-43	164.00
IUUC-Nfi-068309	Neosartorya fischeri	69.38	3.00e-61	224.00
IUUC-Ncr-068658	Neurospora crassa	66.89	3.00e-55	205.00
IUUC-Nle-070101	Nomascus leucogenys	56.36	8.00e-43	164.00
IUUC-Opr-070881	Ochotona princeps	56.36	8.00e-43	164.00
IUUC-Ont-071529	Oreochromis niloticus	56.36	8.00e-43	164.00
IUUC-Oan-073000	Ornithorhynchus anatinus	74.14	3.00e-23	97.40
IUUC-Ocu-073780	Oryctolagus cuniculus	56.36	8.00e-43	164.00
IUUC-Oba-075110	Oryza barthii	47.10	8.00e-35	137.00
IUUC-Obr-076716	Oryza brachyantha	48.17	6.00e-34	134.00
IUUC-Ogl-077257	Oryza glaberrima	51.61	8.00e-39	150.00
IUUC-Ogu-078813	Oryza glumaepatula	49.36	3.00e-35	138.00
IUUC-Oin-080141	Oryza indica	51.61	8.00e-39	150.00
IUUC-Olo-080834	Oryza longistaminata	41.40	8.00e-33	130.00
IUUC-Ome-081330	Oryza meridionalis	44.24	3.00e-31	125.00
IUUC-Oni-082067	Oryza nivara	50.34	8.00e-36	140.00
IUUC-Opu-083927	Oryza punctata	48.39	2.00e-31	126.00
IUUC-Oru-084769	Oryza rufipogon	47.10	3.00e-35	139.00
IUUC-Osa-085479	Oryza sativa	47.10	3.00e-35	139.00
IUUC-Ola-087270	Oryzias latipes	56.36	8.00e-43	164.00
IUUC-Olu-087667	Ostreococcus lucimarinus	52.20	1.00e-41	159.00
IUUC-Oga-089073	Otolemur garnettii	56.36	8.00e-43	164.00
IUUC-Oar-089391	Ovis aries	51.55	4.00e-37	144.00
IUUC-Ptr-090872	Pan troglodytes	54.27	4.00e-41	158.00
IUUC-Pan-091780	Papio anubis	56.36	8.00e-43	164.00
IUUC-Psi-093135	Pelodiscus sinensis	56.36	8.00e-43	164.00
IUUC-Pno-094810	Phaeosphaeria nodorum	62.50	3.00e-44	168.00
IUUC-Ppa-095244	Physcomitrella patens	53.85	8.00e-41	157.00
IUUC-Pfo-097529	Poecilia formosa	56.36	8.00e-43	164.00
IUUC-Pab-098533	Pongo abelii	56.36	8.00e-43	164.00
IUUC-Pop-099897	Populus trichocarpa	53.16	3.00e-39	152.00
IUUC-Pca-100783	Procavia capensis	47.27	4.00e-32	128.00
IUUC-Ppe-101410	Prunus persica	50.63	1.00e-40	156.00
IUUC-Pva-102901	Pteropus vampyrus	56.36	8.00e-43	164.00
IUUC-Pgr-103499	Puccinia graminis	68.59	5.00e-60	221.00
IUUC-Ptt-103874	Puccinia triticina	71.54	2.00e-52	196.00
IUUC-Pte-104224	Pyrenophora teres	63.64	7.00e-41	157.00
IUUC-Pyt-104750	Pyrenophora triticirepentis	63.64	9.00e-41	157.00
IUUC-Rno-105499	Rattus norvegicus	56.36	8.00e-43	164.00
IUUC-Sce-106387	Saccharomyces cerevisiae	48.45	3.00e-48	182.00
IUUC-Sja-107902	Schizosaccharomyces japonicus	86.34	6.00e-84	300.00
IUUC-Ssl-108591	Sclerotinia sclerotiorum	67.12	2.00e-55	205.00
IUUC-Smo-109307	Selaginella moellendorffii	52.23	2.00e-39	152.00
IUUC-Sit-110435	Setaria italica	47.80	5.00e-32	128.00
IUUC-Sly-111529	Solanum lycopersicum	51.61	2.00e-35	139.00
IUUC-Stu-112023	Solanum tuberosum	51.61	3.00e-35	138.00
IUUC-Sar-112973	Sorex araneus	51.52	7.00e-35	137.00
IUUC-Sbi-114666	Sorghum bicolor	50.94	4.00e-35	138.00
IUUC-Sre-115178	Sporisorium reilianum	67.09	3.00e-62	228.00
IUUC-Tgu-116474	Taeniopygia guttata	56.36	8.00e-43	164.00
IUUC-Tru-118429	Takifugu rubripes	56.36	8.00e-43	164.00
IUUC-Tsy-118896	Tarsius syrichta	56.36	8.00e-43	164.00
IUUC-Tni-119960	Tetraodon nigroviridis	56.36	8.00e-43	164.00
IUUC-Tca-121022	Theobroma cacao	52.56	5.00e-36	141.00
IUUC-Tre-122004	Trichoderma reesei	65.07	6.00e-50	187.00
IUUC-Tvi-122449	Trichoderma virens	65.75	5.00e-50	187.00
IUUC-Tae-123642	Triticum aestivum	48.78	3.00e-38	148.00
IUUC-Tur-126200	Triticum urartu	51.28	6.00e-39	150.00
IUUC-Tme-127078	Tuber melanosporum	71.43	2.00e-60	222.00
IUUC-Tbe-127720	Tupaia belangeri	56.36	8.00e-43	164.00
IUUC-Ttr-129035	Tursiops truncatus	56.36	8.00e-43	164.00
IUUC-Uma-129517	Ustilago maydis	67.09	5.00e-61	224.00
IUUC-Vda-129691	Verticillium dahliae	66.20	1.00e-50	190.00
IUUC-Vpa-130128	Vicugna pacos	56.36	9.00e-43	163.00
IUUC-Vvi-130876	Vitis vinifera	51.61	5.00e-41	157.00
IUUC-Xtr-132393	Xenopus tropicalis	56.36	8.00e-43	164.00
IUUC-Xma-133603	Xiphophorus maculatus	56.36	8.00e-43	164.00
IUUC-Yli-134499	Yarrowia lipolytica	67.08	5.00e-59	217.00
IUUC-Zma-135000	Zea mays	47.13	1.00e-33	133.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence