iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069847

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01193500

Gene Name

ATXN3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000017126.2	ENSNLET00000021832.2	ENSNLEP00000020791.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UIM	1.40e-07	30.7	224	242
UBD/Alpha-Helix/UIM	8.9e-06	16.2	244	260
UBD/Alpha-Helix/UIM	8.3e-05	13.3	334	350

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UIM

   S: 1    dEdeeLqlAlalSlqEeee 19
           +++e+Lq+AlalS+qE ++
   Q: 224  EDEEDLQRALALSRQEIDM 242
           69**************886 PP

UBD/Alpha-Helix/UIM

   S: 1    dEdeeLqlAlalSlqEe 17
           dE+++L++A++lS+q  
   Q: 244  DEEADLRRAIQLSMQGS 260
           7*************976 PP

UBD/Alpha-Helix/UIM

   S: 1    dEdeeLqlAlalSlqEe 17
           +E+++Lq A+++Sl+ +
   Q: 334  SEEDMLQAAVTMSLETV 350
           7*************986 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MESIFHEKQE GSLCAQHCLN NLLQGEYFSP VELSSIAHQL DEEERMRMAE GGVTSEDYRT 60
FLQQPSGNMD DSGFFSIQVI SNALKVWGLE LILFNSPEYQ RLRIDPINER SFICNYKEHW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTTGGCTCC AGACAAATAA ACATGGAGTC CATTTTCCAC GAGAAAGTGA GTGTCCGCGT 60
TCGGTGGGGA GCTGTCTGCC GCGCGGTGGC GGGCGTGGAG CGCTGCATCA CCGCCTCCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033865--Ataxin-3
IPR006155--Josephin
IPR009068--S15_NS1_RNA-bd
IPR011990--TPR-like_helical_dom
IPR003903--UIM_dom

PROSITE

PS50957--JOSEPHIN
PS50330--UIM

Pfam

PF02099--Josephin
PF02809--UIM

SMART

SM01246--Josephin
SM00726--UIM

Gene Ontology

GO:0005829--C:cytosol
GO:0005789--C:endoplasmic reticulum membrane
GO:0005730--C:nucleolus
GO:0005886--C:plasma membrane
GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0061578--F:Lys63-specific deubiquitinase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0030036--P:actin cytoskeleton organization
GO:0045104--P:intermediate filament cytoskeleton organization
GO:0000226--P:microtubule cytoskeleton organization
GO:1904294--P:positive regulation of ERAD pathway
GO:1904379--P:protein localization to cytosolic proteasome complex involved in ERAD pathway
GO:0010810--P:regulation of cell-substrate adhesion

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002015	Ailuropoda melanoleuca	87.46	3.00e-172	597.00
IUUC-Apl-003210	Anas platyrhynchos	70.52	7.00e-131	459.00
IUUC-Aca-005171	Anolis carolinensis	64.91	3.00e-111	394.00
IUUC-Afu-009069	Aspergillus fumigatus	30.67	2.20e-01	28.50
IUUC-Ame-010715	Astyanax mexicanus	64.33	2.00e-107	381.00
IUUC-Bta-013538	Bos taurus	80.59	4.00e-164	570.00
IUUC-Bci-013745	Botrytis cinerea	35.82	6.30e-02	32.70
IUUC-Cja-018840	Callithrix jacchus	81.59	3.00e-168	584.00
IUUC-Cfa-021035	Canis familiaris	89.17	2.00e-177	614.00
IUUC-Cpo-021776	Cavia porcellus	82.09	6.00e-167	580.00
IUUC-Cho-024878	Choloepus hoffmanni	87.14	6.00e-169	586.00
IUUC-Cgl-026754	Colletotrichum gloeosporioides	55.56	4.90e-01	30.40
IUUC-Dre-027506	Danio rerio	60.48	3.00e-74	271.00
IUUC-Dno-029172	Dasypus novemcinctus	86.46	7.00e-174	602.00
IUUC-Dor-030900	Dipodomys ordii	73.43	1.00e-134	472.00
IUUC-Eca-034338	Equus caballus	89.46	7.00e-173	599.00
IUUC-Fca-035441	Felis catus	90.21	6.00e-71	259.00
IUUC-Fal-037525	Ficedula albicollis	68.66	1.00e-119	422.00
IUUC-Gmo-039718	Gadus morhua	64.60	4.00e-96	344.00
IUUC-Gga-040774	Gallus gallus	70.89	1.00e-136	479.00
IUUC-Gac-041671	Gasterosteus aculeatus	65.41	3.00e-93	334.00
IUUC-Gma-042801	Glycine max	38.92	5.00e-33	134.00
IUUC-Ggo-044759	Gorilla gorilla	81.14	8.00e-136	476.00
IUUC-Hsa-046591	Homo sapiens	88.51	8.00e-168	582.00
IUUC-Itr-048851	Ictidomys tridecemlineatus	70.18	1.00e-116	412.00
IUUC-Lch-049519	Latimeria chalumnae	64.31	5.00e-96	343.00
IUUC-Loc-051816	Lepisosteus oculatus	61.11	2.00e-115	409.00
IUUC-Laf-053784	Loxodonta africana	84.68	5.00e-172	596.00
IUUC-Mcc-055283	Macaca mulatta	92.76	0.00e+00	644.00
IUUC-Meu-056589	Macropus eugenii	70.64	6.00e-137	479.00
IUUC-Mga-059301	Meleagris gallopavo	69.54	4.00e-139	487.00
IUUC-Mmr-061038	Microcebus murinus	89.56	3.00e-179	620.00
IUUC-Mdo-062927	Monodelphis domestica	75.14	5.00e-137	480.00
IUUC-Mmu-063600	Mus musculus	78.89	2.00e-148	518.00
IUUC-Mpu-065897	Mustela putorius furo	88.34	6.00e-144	503.00
IUUC-Mlu-067543	Myotis lucifugus	86.76	3.00e-145	508.00
IUUC-Opr-070550	Ochotona princeps	85.47	2.00e-163	567.00
IUUC-Ont-071723	Oreochromis niloticus	62.06	6.00e-95	340.00
IUUC-Oan-073569	Ornithorhynchus anatinus	73.32	4.00e-146	510.00
IUUC-Ocu-074632	Oryctolagus cuniculus	83.85	5.00e-167	580.00
IUUC-Ola-087566	Oryzias latipes	66.44	4.00e-97	347.00
IUUC-Oga-088617	Otolemur garnettii	68.82	2.00e-120	424.00
IUUC-Oar-090052	Ovis aries	81.15	1.00e-164	572.00
IUUC-Ptr-091435	Pan troglodytes	92.50	0.00e+00	642.00
IUUC-Psi-093313	Pelodiscus sinensis	80.83	1.00e-116	412.00
IUUC-Pno-095003	Phaeosphaeria nodorum	34.52	1.20e-01	32.30
IUUC-Pfo-097327	Poecilia formosa	64.65	2.00e-97	348.00
IUUC-Pab-098611	Pongo abelii	90.58	8.00e-152	529.00
IUUC-Pca-101022	Procavia capensis	99.11	2.00e-65	242.00
IUUC-Ppe-101545	Prunus persica	41.07	7.00e-35	140.00
IUUC-Pva-102844	Pteropus vampyrus	89.17	6.00e-176	609.00
IUUC-Rno-104896	Rattus norvegicus	79.22	1.00e-157	548.00
IUUC-Sha-107106	Sarcophilus harrisii	79.02	2.00e-157	548.00
IUUC-Sar-113534	Sorex araneus	74.43	7.00e-140	489.00
IUUC-Ssc-115274	Sus scrofa	87.19	4.00e-177	613.00
IUUC-Tgu-117426	Taeniopygia guttata	71.67	9.00e-130	456.00
IUUC-Tru-118059	Takifugu rubripes	64.77	4.00e-94	337.00
IUUC-Tsy-119448	Tarsius syrichta	83.66	5.00e-88	317.00
IUUC-Tni-120681	Tetraodon nigroviridis	89.15	6.00e-62	228.00
IUUC-Tca-121442	Theobroma cacao	34.58	3.00e-37	148.00
IUUC-Tbe-127638	Tupaia belangeri	83.24	1.00e-156	545.00
IUUC-Ttr-129288	Tursiops truncatus	77.44	2.00e-149	521.00
IUUC-Vpa-130788	Vicugna pacos	87.64	3.00e-172	597.00
IUUC-Xtr-132147	Xenopus tropicalis	62.90	2.00e-114	405.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence